Gene Card
Best human hits
EXD3; EXOSC10
Species
Unique Gene ID
Phfumi.g00003647
Gene Model ID
Phfumi.CG.MTP2014.S1379.g03647
Location
S1379:17618..21725
Transcript Models and Sequences
Phfumi.CG.MTP2014.S1379.g03647.01.t
Phfumi.CG.MTP2014.S1379.g03647.02.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
HRDC_dom | Pfam | HRDC domain |
HRDC_dom | SMART | HRDC domain |
Exosome-assoc_fac_Rrp6_N | Pfam | Exosome-associated factor Rrp6, N-terminal |
RNaseH-like_sf | SUPERFAMILY | Ribonuclease H-like superfamily |
HRDC-like_sf | SUPERFAMILY | HRDC-like superfamily |
3'-5'_exonuclease_dom | Pfam | 3'-5' exonuclease domain |
3'-5'_exonuclease_dom | SMART | 3'-5' exonuclease domain |
HRDC_dom | ProSiteProfiles | HRDC domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | Orthology | biological process |
nuclear-transcribed mRNA catabolic process | Orthology | biological process |
nucleic acid binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
catalytic activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
intracellular | Orthology | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
nucleobase-containing compound metabolic process | Orthology | biological process |
RNA processing | Orthology | biological process |
membrane | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
metal ion binding | Blast | molecular function |
RNA metabolic process | Orthology | biological process |
nuclear lumen | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
intracellular part | Orthology | cellular component |
organelle organization | Orthology | biological process |
DNA metabolic process | Orthology | biological process |
transferase activity, transferring phosphorus-containing groups | Orthology | molecular function |
intracellular organelle part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
RNA catabolic process | Orthology | biological process |
mRNA processing | Orthology | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
3'-5'-exoribonuclease activity | Hs | molecular function |
nuclear exosome (RNase complex) | Hs | cellular component |
exosome (RNase complex) | Hs | cellular component |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | Hs | biological process |
maturation of 5.8S rRNA | Hs | biological process |
nuclear-transcribed mRNA catabolic process | Hs | biological process |
nucleic acid binding | Hs | molecular function |
RNA binding | Hs | molecular function |
catalytic activity | Hs | molecular function |
nuclease activity | Hs | molecular function |
exonuclease activity | Hs | molecular function |
exoribonuclease activity | Hs | molecular function |
protein binding | Hs | molecular function |
intracellular | Hs | cellular component |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
nucleolus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
nucleobase-containing compound metabolic process | Hs | biological process |
rRNA processing | Hs | biological process |
RNA processing | Hs | biological process |
3'-5' exonuclease activity | Hs | molecular function |
membrane | Hs | cellular component |
hydrolase activity | Hs | molecular function |
negative regulation of telomere maintenance via telomerase | Hs | biological process |
transcriptionally active chromatin | Hs | cellular component |
cellular metabolic process | Hs | biological process |
telomerase RNA binding | Hs | molecular function |
nuclear mRNA surveillance | Hs | biological process |
CUT catabolic process | Hs | biological process |
nuclear polyadenylation-dependent rRNA catabolic process | Hs | biological process |
nuclear retention of unspliced pre-mRNA at the site of transcription | Hs | biological process |
nucleic acid phosphodiester bond hydrolysis | Hs | biological process |
RNA phosphodiester bond hydrolysis, exonucleolytic | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 568 | 0.0 |
3'-5'-exoribonuclease activity | Hs | molecular function | 568 | 0.0 |
nuclear exosome (RNase complex) | Hs | cellular component | 568 | 0.0 |
exosome (RNase complex) | Hs | cellular component | 568 | 0.0 |
nucleic acid binding | Hs | molecular function | 568 | 0.0 |
RNA binding | Hs | molecular function | 568 | 0.0 |
catalytic activity | Hs | molecular function | 568 | 0.0 |
nuclease activity | Hs | molecular function | 568 | 0.0 |
exonuclease activity | Hs | molecular function | 568 | 0.0 |
exoribonuclease activity | Hs | molecular function | 568 | 0.0 |
protein binding | Hs | molecular function | 568 | 0.0 |
intracellular | Hs | cellular component | 568 | 0.0 |
nucleus | Hs | cellular component | 568 | 0.0 |
nucleoplasm | Hs | cellular component | 568 | 0.0 |
nucleolus | Hs | cellular component | 568 | 0.0 |
cytoplasm | Hs | cellular component | 568 | 0.0 |
cytosol | Hs | cellular component | 568 | 0.0 |
3'-5' exonuclease activity | Hs | molecular function | 568 | 0.0 |
membrane | Hs | cellular component | 568 | 0.0 |
hydrolase activity | Hs | molecular function | 568 | 0.0 |
transcriptionally active chromatin | Hs | cellular component | 568 | 0.0 |
metal ion binding | Hs | molecular function | 42.0 | 0.002 |
telomerase RNA binding | Hs | molecular function | 568 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
nucleotide binding | SUPERFAMILY | molecular function | 1.23E-22 |
nuclear exosome (RNase complex) | Pfam | cellular component | 1.4E-14 |
nucleic acid binding | Pfam | molecular function | 2.2E-46 |
catalytic activity | SUPERFAMILY | molecular function | 1.23E-22 |
intracellular | SMART | cellular component | 9.8E-14 |
nucleobase-containing compound metabolic process | Pfam | biological process | 2.2E-46 |
RNA processing | Pfam | biological process | 1.4E-14 |
3'-5' exonuclease activity | Pfam | molecular function | 2.2E-46 |
cellular metabolic process | SUPERFAMILY | biological process | 1.23E-22 |