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GENE CARD

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Gene Card

Best human hits

FURIN; PCSK2; PCSK4

Species

P.fumigata

Unique Gene ID

Phfumi.g00003744

Gene Model ID

Phfumi.CG.MTP2014.S1459.g03744

Location

S1459:2686..12516

Transcript Models and Sequences

  Phfumi.CG.MTP2014.S1459.g03744.01.t

External Database Gene Card

External database links

No result

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WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

8 results

IPR Term Analysis Definition
Peptidase_S8_His-AS ProSitePatterns Peptidase S8, subtilisin, His-active site
Peptidase_S8/S53_dom Pfam Peptidase S8/S53 domain
Peptidase_S8/S53_dom_sf Gene3D Peptidase S8/S53 domain superfamily
Peptidase_S8_Ser-AS ProSitePatterns Peptidase S8, subtilisin, Ser-active site
Peptidase_S8/S53_dom_sf SUPERFAMILY Peptidase S8/S53 domain superfamily
Peptidase_S8_Asp-AS ProSitePatterns Peptidase S8, subtilisin, Asp-active site
Kexin/furin CDD Kexin/furin catalytic domain
Peptidase_S8_subtilisin-rel PRINTS Peptidase S8, subtilisin-related

GOSlim

36 results

GO Term Annotation Origin Type
Golgi membrane Blast cellular component
endopeptidase activity Orthology molecular function
serine-type endopeptidase activity Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
nucleus Orthology cellular component
endosome Blast cellular component
endoplasmic reticulum Blast cellular component
Golgi apparatus Blast cellular component
plasma membrane Blast cellular component
proteolysis Orthology biological process
nervous system development Orthology biological process
peptidase activity Orthology molecular function
serine-type peptidase activity Orthology molecular function
cell surface Blast cellular component
membrane Orthology cellular component
integral component of membrane Blast cellular component
hydrolase activity Orthology molecular function
cytoplasmic vesicle Orthology cellular component
neuronal cell body Orthology cellular component
intracellular membrane-bounded organelle Orthology cellular component
membrane raft Blast cellular component
metal ion binding Blast molecular function
extracellular exosome Blast cellular component
gene expression Orthology biological process
peptide metabolic process Orthology biological process
endomembrane system Orthology cellular component
intracellular organelle part Orthology cellular component
intracellular organelle lumen Orthology cellular component
enzyme binding Blast molecular function
whole membrane Blast cellular component
bounding membrane of organelle Blast cellular component
enzyme regulator activity Blast molecular function
Golgi apparatus part Blast cellular component
binding Blast molecular function

GO (Orthology)

24 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
endopeptidase activity Hs molecular function
serine-type endopeptidase activity Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
extracellular space Hs cellular component
nucleus Hs cellular component
proteolysis Hs biological process
nervous system development Hs biological process
peptidase activity Hs molecular function
serine-type peptidase activity Hs molecular function
membrane Hs cellular component
protein processing Hs biological process
peptide hormone processing Hs biological process
protein autoprocessing Hs biological process
hydrolase activity Hs molecular function
insulin processing Hs biological process
transport vesicle Hs cellular component
secretory granule Hs cellular component
dendrite Hs cellular component
cytoplasmic vesicle Hs cellular component
secretory granule lumen Hs cellular component
neuronal cell body Hs cellular component
perikaryon Hs cellular component
intracellular membrane-bounded organelle Hs cellular component

GO (Blast)

38 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
Golgi membrane Hs cellular component 268 4.19e-85
acrosomal vesicle Hs cellular component 265 4.49e-84
protease binding Hs molecular function 268 4.19e-85
acrosomal membrane Hs cellular component 265 4.49e-84
endopeptidase activity Hs molecular function 429 6.22e-149
serine-type endopeptidase activity Hs molecular function 429 6.22e-149
serine-type endopeptidase inhibitor activity Hs molecular function 268 4.19e-85
protein binding Hs molecular function 429 6.22e-149
extracellular region Hs cellular component 429 6.22e-149
extracellular space Hs cellular component 429 6.22e-149
nucleus Hs cellular component 429 6.22e-149
endosome Hs cellular component 268 4.19e-85
endoplasmic reticulum Hs cellular component 268 4.19e-85
Golgi apparatus Hs cellular component 268 4.19e-85
Golgi lumen Hs cellular component 268 4.19e-85
trans-Golgi network Hs cellular component 268 4.19e-85
plasma membrane Hs cellular component 268 4.19e-85
peptidase activity Hs molecular function 429 6.22e-149
serine-type peptidase activity Hs molecular function 429 6.22e-149
cell surface Hs cellular component 268 4.19e-85
endosome membrane Hs cellular component 268 4.19e-85
membrane Hs cellular component 429 6.22e-149
integral component of membrane Hs cellular component 268 4.19e-85
hydrolase activity Hs molecular function 429 6.22e-149
transport vesicle Hs cellular component 429 6.22e-149
trans-Golgi network transport vesicle Hs cellular component 268 4.19e-85
secretory granule Hs cellular component 429 6.22e-149
dendrite Hs cellular component 429 6.22e-149
cytoplasmic vesicle Hs cellular component 429 6.22e-149
secretory granule lumen Hs cellular component 429 6.22e-149
peptide binding Hs molecular function 268 4.19e-85
neuronal cell body Hs cellular component 429 6.22e-149
perikaryon Hs cellular component 429 6.22e-149
intracellular membrane-bounded organelle Hs cellular component 429 6.22e-149
membrane raft Hs cellular component 268 4.19e-85
metal ion binding Hs molecular function 268 4.19e-85
nerve growth factor binding Hs molecular function 268 4.19e-85
extracellular exosome Hs cellular component 268 4.19e-85

GO (InterProScan)

2 results

GO Term Analysis Type e-value
serine-type endopeptidase activity Gene3D molecular function 2.2E-61
proteolysis Gene3D biological process 2.2E-61