Aniseed - Gene card

Gene Card

Best human hits

EZH1; EZH2; SUV39H1

Species

P.fumigata

Unique Gene ID

Phfumi.g00003992

Gene Model ID

Phfumi.CG.MTP2014.S1679.g03992

Location

S1679:15610..22038

Transcript Models and Sequences

Phfumi.CG.MTP2014.S1679.g03992.01.t

External Database Gene Card

External database links

No result

Collections

WashU Genome Browser

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Genomicus Synteny Browser

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term	Analysis	Definition
SET_dom	SMART	SET domain
CXC_dom	ProSiteProfiles	CXC domain
SET_dom	Pfam	SET domain
SET_dom	ProSiteProfiles	SET domain
Tesmin/TSO1-like_CXC	SMART	Tesmin/TSO1-like CXC domain
EZH1	PANTHER	Histone-lysine N-methyltransferase EZH1

GOSlim

59 results

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription regulatory region sequence-specific DNA binding	Blast	molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Orthology	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
DNA binding	Orthology	molecular function
chromatin binding	Orthology	molecular function
RNA binding	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
zinc ion binding	Blast	molecular function
anatomical structure morphogenesis	Orthology	biological process
regulation of gene expression	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
transferase activity	Orthology	molecular function
cell differentiation	Orthology	biological process
regulation of cell proliferation	Orthology	biological process
positive regulation of GTPase activity	Orthology	biological process
sequence-specific DNA binding	Orthology	molecular function
transcription regulatory region DNA binding	Orthology	molecular function
negative regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
metal ion binding	Blast	molecular function
protein N-terminus binding	Blast	molecular function
intracellular non-membrane-bounded organelle	Orthology	cellular component
nuclear lumen	Orthology	cellular component
RNA polymerase II regulatory region sequence-specific DNA binding	Orthology	molecular function
regulation of cellular metabolic process	Orthology	biological process
protein phosphorylation	Orthology	biological process
DNA metabolic process	Orthology	biological process
organelle organization	Orthology	biological process
metabolic process	Orthology	biological process
animal organ development	Orthology	biological process
cell development	Orthology	biological process
generation of neurons	Orthology	biological process
cellular protein modification process	Orthology	biological process
brain development	Orthology	biological process
response to lipid	Orthology	biological process
nucleoplasm part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
macromolecular complex binding	Orthology	molecular function
positive regulation of catalytic activity	Orthology	biological process
intracellular signal transduction	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
regulation of molecular function	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
multicellular organism development	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
cellular response to stress	Orthology	biological process
response to oxidative stress	Orthology	biological process
protein localization to organelle	Orthology	biological process
neuron projection development	Orthology	biological process
G1/S transition of mitotic cell cycle	Orthology	biological process
intracellular organelle part	Blast	cellular component

GO (Orthology)

64 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
nuclear chromatin	Hs	cellular component
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II core promoter sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
core promoter binding	Hs	molecular function
regulation of protein phosphorylation	Hs	biological process
DNA binding	Hs	molecular function
chromatin binding	Hs	molecular function
RNA binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
DNA methylation	Hs	biological process
chromatin organization	Hs	biological process
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
methyltransferase activity	Hs	molecular function
anatomical structure morphogenesis	Hs	biological process
regulation of gene expression	Hs	biological process
negative regulation of gene expression	Hs	biological process
positive regulation of epithelial to mesenchymal transition	Hs	biological process
regulation of gliogenesis	Hs	biological process
protein-lysine N-methyltransferase activity	Hs	molecular function
histone methylation	Hs	biological process
transferase activity	Hs	molecular function
histone-lysine N-methyltransferase activity	Hs	molecular function
cerebellar cortex development	Hs	biological process
chromatin DNA binding	Hs	molecular function
methylation	Hs	biological process
response to estradiol	Hs	biological process
negative regulation of transcription elongation from RNA polymerase II promoter	Hs	biological process
histone lysine methylation	Hs	biological process
ESC/E(Z) complex	Hs	cellular component
histone methyltransferase activity	Hs	molecular function
regulation of cell proliferation	Hs	biological process
regulation of circadian rhythm	Hs	biological process
ribonucleoprotein complex binding	Hs	molecular function
positive regulation of MAP kinase activity	Hs	biological process
negative regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
positive regulation of GTPase activity	Hs	biological process
sequence-specific DNA binding	Hs	molecular function
transcription regulatory region DNA binding	Hs	molecular function
pronucleus	Hs	cellular component
negative regulation of epidermal cell differentiation	Hs	biological process
negative regulation of gene expression, epigenetic	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
histone methyltransferase activity (H3-K27 specific)	Hs	molecular function
negative regulation of retinoic acid receptor signaling pathway	Hs	biological process
rhythmic process	Hs	biological process
regulation of neurogenesis	Hs	biological process
cellular response to hydrogen peroxide	Hs	biological process
G1 to G0 transition	Hs	biological process
histone H3-K27 methylation	Hs	biological process
primary miRNA binding	Hs	molecular function
protein localization to chromatin	Hs	biological process
positive regulation of protein serine/threonine kinase activity	Hs	biological process
histone H3-K27 trimethylation	Hs	biological process
positive regulation of dendrite development	Hs	biological process
promoter-specific chromatin binding	Hs	molecular function
negative regulation of G1/S transition of mitotic cell cycle	Hs	biological process

GO (Blast)

39 results

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
chromosome, centromeric region	Hs	cellular component	100	1.57e-23
nuclear chromatin	Hs	cellular component	501	4.35e-174
heterochromatin	Hs	cellular component	100	1.57e-23
condensed nuclear chromosome	Hs	cellular component	100	1.57e-23
transcription regulatory region sequence-specific DNA binding	Hs	molecular function	100	1.57e-23
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	501	4.35e-174
RNA polymerase II core promoter sequence-specific DNA binding	Hs	molecular function	501	4.35e-174
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	501	4.35e-174
core promoter binding	Hs	molecular function	501	4.35e-174
DNA binding	Hs	molecular function	501	4.35e-174
chromatin binding	Hs	molecular function	501	4.35e-174
RNA binding	Hs	molecular function	501	4.35e-174
protein binding	Hs	molecular function	501	4.35e-174
nucleus	Hs	cellular component	501	4.35e-174
nuclear lamina	Hs	cellular component	100	1.57e-23
nucleoplasm	Hs	cellular component	501	4.35e-174
chromatin silencing complex	Hs	cellular component	100	1.57e-23
chromosome	Hs	cellular component	100	1.57e-23
cytoplasm	Hs	cellular component	501	4.35e-174
methyltransferase activity	Hs	molecular function	501	4.35e-174
zinc ion binding	Hs	molecular function	100	1.57e-23
S-adenosylmethionine-dependent methyltransferase activity	Hs	molecular function	100	1.57e-23
protein-lysine N-methyltransferase activity	Hs	molecular function	501	4.35e-174
transferase activity	Hs	molecular function	501	4.35e-174
histone-lysine N-methyltransferase activity	Hs	molecular function	501	4.35e-174
chromatin DNA binding	Hs	molecular function	501	4.35e-174
rDNA heterochromatin	Hs	cellular component	100	1.57e-23
ESC/E(Z) complex	Hs	cellular component	501	4.35e-174
histone methyltransferase activity	Hs	molecular function	501	4.35e-174
ribonucleoprotein complex binding	Hs	molecular function	501	4.35e-174
sequence-specific DNA binding	Hs	molecular function	501	4.35e-174
transcription regulatory region DNA binding	Hs	molecular function	501	4.35e-174
pronucleus	Hs	cellular component	501	4.35e-174
metal ion binding	Hs	molecular function	100	1.57e-23
histone methyltransferase activity (H3-K9 specific)	Hs	molecular function	100	1.57e-23
histone methyltransferase activity (H3-K27 specific)	Hs	molecular function	501	4.35e-174
protein N-terminus binding	Hs	molecular function	100	1.57e-23
primary miRNA binding	Hs	molecular function	501	4.35e-174
promoter-specific chromatin binding	Hs	molecular function	501	4.35e-174

GO (InterProScan)

3 results

GO Term	Analysis	Type	e-value
protein binding	SMART	molecular function	3.2E-35
histone-lysine N-methyltransferase activity	PANTHER	molecular function	6.4E-175
histone H3-K27 methylation	PANTHER	biological process	6.4E-175