Gene Card
Best human hits
CTBP1; GRHPR; PHGDH
Species
Unique Gene ID
Phfumi.g00004228
Gene Model ID
Phfumi.CG.MTP2014.S1870.g04228
Location
S1870:1935..5697
Transcript Models and Sequences
Phfumi.CG.MTP2014.S1870.g04228.01.t
Phfumi.CG.MTP2014.S1870.g04228.02.t
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
D-isomer_DH_NAD-bd | Pfam | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain |
ASB_dom_sf | SUPERFAMILY | Allosteric substrate binding domain superfamily |
D-isomer_DH_CS1 | ProSitePatterns | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 |
D-isomer_2_OHA_DH_cat_dom | Pfam | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain |
NAD(P)-bd_dom_sf | SUPERFAMILY | NAD(P)-binding domain superfamily |
ASB_dom_sf | Gene3D | Allosteric substrate binding domain superfamily |
PGDH | TIGRFAM | D-3-phosphoglycerate dehydrogenase |
GO Term | Annotation Origin | Type |
---|---|---|
transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
protein binding | Blast | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
cytoplasm | Blast | cellular component |
cytosol | Orthology | cellular component |
brain development | Orthology | biological process |
protein C-terminus binding | Blast | molecular function |
transcription factor binding | Blast | molecular function |
metabolic process | Orthology | biological process |
regulation of gene expression | Orthology | biological process |
neurogenesis | Orthology | biological process |
neuron projection development | Orthology | biological process |
protein homodimerization activity | Blast | molecular function |
myelin sheath | Orthology | cellular component |
oxidation-reduction process | Orthology | biological process |
extracellular exosome | Orthology | cellular component |
catalytic activity | Orthology | molecular function |
cellular metabolic process | Orthology | biological process |
cellular biosynthetic process | Orthology | biological process |
animal organ development | Orthology | biological process |
central nervous system development | Orthology | biological process |
cell development | Orthology | biological process |
nervous system development | Orthology | biological process |
nucleotide binding | Orthology | molecular function |
coenzyme binding | Orthology | molecular function |
intracellular part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
peroxisome | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
small molecule binding | Blast | molecular function |
anion binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
phosphoglycerate dehydrogenase activity | Hs | molecular function |
cytosol | Hs | cellular component |
glutamine metabolic process | Hs | biological process |
glycine metabolic process | Hs | biological process |
L-serine metabolic process | Hs | biological process |
L-serine biosynthetic process | Hs | biological process |
brain development | Hs | biological process |
metabolic process | Hs | biological process |
cellular amino acid biosynthetic process | Hs | biological process |
electron carrier activity | Hs | molecular function |
gamma-aminobutyric acid metabolic process | Hs | biological process |
regulation of gene expression | Hs | biological process |
oxidoreductase activity | Hs | molecular function |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Hs | molecular function |
spinal cord development | Hs | biological process |
glial cell development | Hs | biological process |
neural tube development | Hs | biological process |
neurogenesis | Hs | biological process |
electron transport chain | Hs | biological process |
L-malate dehydrogenase activity | Hs | molecular function |
neuron projection development | Hs | biological process |
myelin sheath | Hs | cellular component |
NAD binding | Hs | molecular function |
oxidation-reduction process | Hs | biological process |
extracellular exosome | Hs | cellular component |
G1 to G0 transition | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
RNA polymerase II transcription corepressor activity | Hs | molecular function | 125 | 2.12e-31 |
transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 125 | 2.12e-31 |
phosphoglycerate dehydrogenase activity | Hs | molecular function | 474 | 1.23e-163 |
protein binding | Hs | molecular function | 125 | 2.12e-31 |
nucleus | Hs | cellular component | 125 | 2.12e-31 |
nucleoplasm | Hs | cellular component | 125 | 2.12e-31 |
transcription factor complex | Hs | cellular component | 125 | 2.12e-31 |
cytoplasm | Hs | cellular component | 125 | 2.12e-31 |
peroxisomal matrix | Hs | cellular component | 120 | 5.63e-30 |
cytosol | Hs | cellular component | 474 | 1.23e-163 |
protein C-terminus binding | Hs | molecular function | 125 | 2.12e-31 |
transcription factor binding | Hs | molecular function | 125 | 2.12e-31 |
glycerate dehydrogenase activity | Hs | molecular function | 120 | 5.63e-30 |
electron carrier activity | Hs | molecular function | 474 | 1.23e-163 |
oxidoreductase activity | Hs | molecular function | 474 | 1.23e-163 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Hs | molecular function | 474 | 1.23e-163 |
hydroxypyruvate reductase activity | Hs | molecular function | 125 | 2.12e-31 |
transcriptional repressor complex | Hs | cellular component | 125 | 2.12e-31 |
protein domain specific binding | Hs | molecular function | 125 | 2.12e-31 |
L-malate dehydrogenase activity | Hs | molecular function | 474 | 1.23e-163 |
glyoxylate reductase (NADP) activity | Hs | molecular function | 125 | 2.12e-31 |
carboxylic acid binding | Hs | molecular function | 120 | 5.63e-30 |
protein homodimerization activity | Hs | molecular function | 125 | 2.12e-31 |
myelin sheath | Hs | cellular component | 474 | 1.23e-163 |
NADP binding | Hs | molecular function | 120 | 5.63e-30 |
NAD binding | Hs | molecular function | 474 | 1.23e-163 |
extracellular exosome | Hs | cellular component | 474 | 1.23e-163 |
NADPH binding | Hs | molecular function | 120 | 5.63e-30 |
repressing transcription factor binding | Hs | molecular function | 125 | 2.12e-31 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
phosphoglycerate dehydrogenase activity | TIGRFAM | molecular function | 6.7E-139 |
L-serine biosynthetic process | TIGRFAM | biological process | 6.7E-139 |
metabolic process | Pfam | biological process | 1.2E-35 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Pfam | molecular function | 1.2E-35 |
NAD binding | Pfam | molecular function | 1.3E-56 |
oxidation-reduction process | Pfam | biological process | 1.3E-56 |