Gene Card
Best human hits
DDX58; DHX58; IFIH1
Species
Unique Gene ID
Phfumi.g00009689
Gene Model ID
Phfumi.CG.MTP2014.S19537.g09689
Location
S19537:435..2826
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
RLR_CTR | ProSiteProfiles | RIG-I-like receptor, C-terminal regulatory domain |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
RLR_C_sf | Gene3D | RIG-I-like receptor, C-terminal domain superfamily |
Helicase_C | SMART | Helicase, C-terminal |
Helicase_C | CDD | Helicase, C-terminal |
Helicase_C | ProSiteProfiles | Helicase, C-terminal |
RLR_CTR | Pfam | RIG-I-like receptor, C-terminal regulatory domain |
Helicase_C | Pfam | Helicase, C-terminal |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
immune system process | Orthology | biological process |
nucleic acid binding | Orthology | molecular function |
DNA binding | Blast | molecular function |
double-stranded DNA binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Blast | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
cytoskeleton | Orthology | cellular component |
plasma membrane | Orthology | cellular component |
zinc ion binding | Orthology | molecular function |
positive regulation of gene expression | Orthology | biological process |
membrane | Orthology | cellular component |
hydrolase activity | Orthology | molecular function |
cell junction | Orthology | cellular component |
ubiquitin protein ligase binding | Orthology | molecular function |
identical protein binding | Orthology | molecular function |
cell projection | Orthology | cellular component |
innate immune response | Orthology | biological process |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
metal ion binding | Orthology | molecular function |
defense response | Orthology | biological process |
nucleoside-triphosphatase activity | Orthology | molecular function |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
cell migration | Orthology | biological process |
cell projection membrane | Orthology | cellular component |
cell leading edge | Orthology | cellular component |
response to organic substance | Orthology | biological process |
transcription factor activity, sequence-specific DNA binding | Orthology | molecular function |
macromolecular complex binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
positive regulation of defense response to virus by host | Hs | biological process |
immune system process | Hs | biological process |
nucleic acid binding | Hs | molecular function |
double-stranded DNA binding | Hs | molecular function |
RNA binding | Hs | molecular function |
double-stranded RNA binding | Hs | molecular function |
single-stranded RNA binding | Hs | molecular function |
helicase activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
cytoskeleton | Hs | cellular component |
plasma membrane | Hs | cellular component |
bicellular tight junction | Hs | cellular component |
zinc ion binding | Hs | molecular function |
detection of virus | Hs | biological process |
response to virus | Hs | biological process |
positive regulation of gene expression | Hs | biological process |
actin cytoskeleton | Hs | cellular component |
membrane | Hs | cellular component |
viral process | Hs | biological process |
protein deubiquitination | Hs | biological process |
hydrolase activity | Hs | molecular function |
cell junction | Hs | cellular component |
regulation of cell migration | Hs | biological process |
ubiquitin protein ligase binding | Hs | molecular function |
negative regulation of type I interferon production | Hs | biological process |
ruffle membrane | Hs | cellular component |
identical protein binding | Hs | molecular function |
positive regulation of transcription factor import into nucleus | Hs | biological process |
cell projection | Hs | cellular component |
response to exogenous dsRNA | Hs | biological process |
innate immune response | Hs | biological process |
positive regulation of transcription from RNA polymerase II promoter | Hs | biological process |
metal ion binding | Hs | molecular function |
positive regulation of sequence-specific DNA binding transcription factor activity | Hs | biological process |
defense response to virus | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 108 | 9.92e-27 |
nucleic acid binding | Hs | molecular function | 108 | 9.92e-27 |
DNA binding | Hs | molecular function | 107 | 3.25e-26 |
double-stranded DNA binding | Hs | molecular function | 108 | 9.92e-27 |
RNA binding | Hs | molecular function | 108 | 9.92e-27 |
double-stranded RNA binding | Hs | molecular function | 108 | 9.92e-27 |
single-stranded RNA binding | Hs | molecular function | 108 | 9.92e-27 |
helicase activity | Hs | molecular function | 108 | 9.92e-27 |
protein binding | Hs | molecular function | 108 | 9.92e-27 |
ATP binding | Hs | molecular function | 108 | 9.92e-27 |
nucleus | Hs | cellular component | 107 | 3.25e-26 |
cytoplasm | Hs | cellular component | 108 | 9.92e-27 |
cytosol | Hs | cellular component | 108 | 9.92e-27 |
cytoskeleton | Hs | cellular component | 108 | 9.92e-27 |
plasma membrane | Hs | cellular component | 108 | 9.92e-27 |
bicellular tight junction | Hs | cellular component | 108 | 9.92e-27 |
zinc ion binding | Hs | molecular function | 108 | 9.92e-27 |
actin cytoskeleton | Hs | cellular component | 108 | 9.92e-27 |
membrane | Hs | cellular component | 108 | 9.92e-27 |
hydrolase activity | Hs | molecular function | 108 | 9.92e-27 |
cell junction | Hs | cellular component | 108 | 9.92e-27 |
ubiquitin protein ligase binding | Hs | molecular function | 108 | 9.92e-27 |
ruffle membrane | Hs | cellular component | 108 | 9.92e-27 |
identical protein binding | Hs | molecular function | 108 | 9.92e-27 |
cell projection | Hs | cellular component | 108 | 9.92e-27 |
ribonucleoprotein complex binding | Hs | molecular function | 107 | 3.25e-26 |
metal ion binding | Hs | molecular function | 108 | 9.92e-27 |
GO Term | Analysis | Type | e-value |
---|