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GENE CARD

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Gene Card

Best human hits

MAP2K1; MAP2K2; MAP2K5

Species

P.fumigata

Unique Gene ID

Phfumi.g00000590

Gene Model ID

Phfumi.CG.MTP2014.S42.g00590

Location

S42:34479..38295

Transcript Models and Sequences

  Phfumi.CG.MTP2014.S42.g00590.01.t
Phfumi.CG.MTP2014.S42.g00590.02.t

External Database Gene Card

External database links

No result

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

6 results

IPR Term Analysis Definition
Prot_kinase_dom ProSiteProfiles Protein kinase domain
Ser/Thr_kinase_AS ProSitePatterns Serine/threonine-protein kinase, active site
Prot_kinase_dom SMART Protein kinase domain
Prot_kinase_dom Pfam Protein kinase domain
Protein_kinase_ATP_BS ProSitePatterns Protein kinase, ATP binding site
Kinase-like_dom_sf SUPERFAMILY Protein kinase-like domain superfamily

GOSlim

61 results

GO Term Annotation Origin Type
nucleotide binding Orthology molecular function
protein kinase activity Orthology molecular function
protein serine/threonine kinase activity Orthology molecular function
protein binding Orthology molecular function
ATP binding Orthology molecular function
extracellular region Orthology cellular component
nucleus Orthology cellular component
cytoplasm Orthology cellular component
mitochondrion Orthology cellular component
early endosome Orthology cellular component
endoplasmic reticulum Orthology cellular component
Golgi apparatus Orthology cellular component
microtubule organizing center Orthology cellular component
cytosol Orthology cellular component
cytoskeleton Orthology cellular component
microtubule Orthology cellular component
plasma membrane Orthology cellular component
focal adhesion Orthology cellular component
protein phosphorylation Orthology biological process
chemotaxis Orthology biological process
signal transduction Orthology biological process
heart development Orthology biological process
protein C-terminus binding Orthology molecular function
negative regulation of cell proliferation Orthology biological process
positive regulation of gene expression Orthology biological process
negative regulation of gene expression Orthology biological process
membrane Orthology cellular component
kinase activity Orthology molecular function
phosphorylation Orthology biological process
transferase activity Orthology molecular function
neuron differentiation Orthology biological process
regulation of apoptotic process Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
metal ion binding Orthology molecular function
protein N-terminus binding Orthology molecular function
perinuclear region of cytoplasm Orthology cellular component
cell motility Orthology biological process
extracellular exosome Orthology cellular component
intracellular signal transduction Orthology biological process
positive regulation of catalytic activity Orthology biological process
positive regulation of signal transduction Orthology biological process
regulation of cellular metabolic process Orthology biological process
endosome Orthology cellular component
intracellular organelle part Orthology cellular component
whole membrane Orthology cellular component
peroxisome Orthology cellular component
bounding membrane of organelle Orthology cellular component
cell junction Orthology cellular component
plasma membrane part Orthology cellular component
animal organ development Orthology biological process
cell differentiation Orthology biological process
enzyme activator activity Orthology molecular function
protein kinase binding Orthology molecular function
immune system process Orthology biological process
axon development Orthology biological process
cellular response to stress Orthology biological process
response to wounding Orthology biological process
axonogenesis Orthology biological process
head development Orthology biological process
cytoskeletal part Blast cellular component
microtubule cytoskeleton Blast cellular component

GO (Orthology)

66 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
MAPK cascade Hs biological process
nucleotide binding Hs molecular function
activation of MAPK activity Hs biological process
regulation of protein phosphorylation Hs biological process
protein kinase activity Hs molecular function
protein serine/threonine kinase activity Hs molecular function
MAP kinase kinase activity Hs molecular function
protein serine/threonine/tyrosine kinase activity Hs molecular function
protein tyrosine kinase activity Hs molecular function
signal transducer, downstream of receptor, with protein tyrosine phosphatase activity Hs molecular function
protein binding Hs molecular function
ATP binding Hs molecular function
extracellular region Hs cellular component
nucleus Hs cellular component
cytoplasm Hs cellular component
mitochondrion Hs cellular component
early endosome Hs cellular component
late endosome Hs cellular component
peroxisomal membrane Hs cellular component
endoplasmic reticulum Hs cellular component
Golgi apparatus Hs cellular component
microtubule organizing center Hs cellular component
cytosol Hs cellular component
cytoskeleton Hs cellular component
microtubule Hs cellular component
plasma membrane Hs cellular component
cell-cell junction Hs cellular component
focal adhesion Hs cellular component
protein phosphorylation Hs biological process
chemotaxis Hs biological process
cell cycle arrest Hs biological process
signal transduction Hs biological process
regulation of mitotic cell cycle Hs biological process
heart development Hs biological process
protein C-terminus binding Hs molecular function
negative regulation of cell proliferation Hs biological process
cytoplasmic side of plasma membrane Hs cellular component
positive regulation of gene expression Hs biological process
negative regulation of gene expression Hs biological process
membrane Hs cellular component
kinase activity Hs molecular function
phosphorylation Hs biological process
transferase activity Hs molecular function
peptidyl-threonine phosphorylation Hs biological process
peptidyl-tyrosine phosphorylation Hs biological process
PDZ domain binding Hs molecular function
neuron differentiation Hs biological process
keratinocyte differentiation Hs biological process
thyroid gland development Hs biological process
regulation of apoptotic process Hs biological process
protein serine/threonine kinase activator activity Hs molecular function
positive regulation of cell differentiation Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
metal ion binding Hs molecular function
protein N-terminus binding Hs molecular function
perinuclear region of cytoplasm Hs cellular component
thymus development Hs biological process
regulation of axon regeneration Hs biological process
cell motility Hs biological process
positive regulation of axonogenesis Hs biological process
face development Hs biological process
extracellular exosome Hs cellular component
positive regulation of ERK1 and ERK2 cascade Hs biological process
positive regulation of protein serine/threonine kinase activity Hs biological process
cellular senescence Hs biological process
scaffold protein binding Hs molecular function

GO (Blast)

38 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nucleotide binding Hs molecular function 457 7.50e-161
protein kinase activity Hs molecular function 457 7.50e-161
protein serine/threonine kinase activity Hs molecular function 457 7.50e-161
MAP kinase kinase activity Hs molecular function 457 7.50e-161
protein serine/threonine/tyrosine kinase activity Hs molecular function 457 7.50e-161
protein tyrosine kinase activity Hs molecular function 457 7.50e-161
signal transducer, downstream of receptor, with protein tyrosine phosphatase activity Hs molecular function 457 7.50e-161
protein binding Hs molecular function 457 7.50e-161
ATP binding Hs molecular function 457 7.50e-161
extracellular region Hs cellular component 446 1.59e-156
nucleus Hs cellular component 457 7.50e-161
cytoplasm Hs cellular component 457 7.50e-161
mitochondrion Hs cellular component 457 7.50e-161
early endosome Hs cellular component 457 7.50e-161
late endosome Hs cellular component 457 7.50e-161
peroxisomal membrane Hs cellular component 446 1.59e-156
endoplasmic reticulum Hs cellular component 457 7.50e-161
Golgi apparatus Hs cellular component 457 7.50e-161
microtubule organizing center Hs cellular component 457 7.50e-161
spindle Hs cellular component 248 2.38e-78
cytosol Hs cellular component 457 7.50e-161
cytoskeleton Hs cellular component 457 7.50e-161
microtubule Hs cellular component 446 1.59e-156
plasma membrane Hs cellular component 457 7.50e-161
cell-cell junction Hs cellular component 446 1.59e-156
focal adhesion Hs cellular component 457 7.50e-161
protein C-terminus binding Hs molecular function 457 7.50e-161
cytoplasmic side of plasma membrane Hs cellular component 446 1.59e-156
membrane Hs cellular component 457 7.50e-161
kinase activity Hs molecular function 457 7.50e-161
transferase activity Hs molecular function 457 7.50e-161
PDZ domain binding Hs molecular function 446 1.59e-156
protein serine/threonine kinase activator activity Hs molecular function 457 7.50e-161
metal ion binding Hs molecular function 446 1.59e-156
protein N-terminus binding Hs molecular function 457 7.50e-161
perinuclear region of cytoplasm Hs cellular component 446 1.59e-156
extracellular exosome Hs cellular component 457 7.50e-161
scaffold protein binding Hs molecular function 457 7.50e-161

GO (InterProScan)

3 results

GO Term Analysis Type e-value
protein kinase activity SMART molecular function 1.0E-74
ATP binding SMART molecular function 1.0E-74
protein phosphorylation SMART biological process 1.0E-74

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