Gene Card
Best human hits
PTPRA; PTPRE; PTPRM
Species
Unique Gene ID
Phfumi.g00002165
Gene Model ID
Phfumi.CG.MTP2014.S488.g02165
Location
S488:19459..23593
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Tyr_Pase_cat | SMART | Protein-tyrosine phosphatase, catalytic |
PTPase_domain | Pfam | PTP type protein phosphatase |
Prot-tyrosine_phosphatase-like | Gene3D | Protein-tyrosine phosphatase-like |
Prot-tyrosine_phosphatase-like | SUPERFAMILY | Protein-tyrosine phosphatase-like |
PTPase_domain | ProSiteProfiles | PTP type protein phosphatase |
PTPase_domain | PRINTS | PTP type protein phosphatase |
TYR_PHOSPHATASE_dom | ProSiteProfiles | Tyrosine specific protein phosphatases domain |
PTPase_domain | SMART | PTP type protein phosphatase |
GO Term | Annotation Origin | Type |
---|---|---|
protein binding | Orthology | molecular function |
intracellular | Blast | cellular component |
nucleus | Blast | cellular component |
cytoplasm | Blast | cellular component |
plasma membrane | Orthology | cellular component |
integral component of plasma membrane | Orthology | cellular component |
protein dephosphorylation | Orthology | biological process |
membrane | Orthology | cellular component |
integral component of membrane | Orthology | cellular component |
dephosphorylation | Orthology | biological process |
hydrolase activity | Orthology | molecular function |
lamellipodium | Blast | cellular component |
neuron projection development | Orthology | biological process |
identical protein binding | Orthology | molecular function |
perinuclear region of cytoplasm | Blast | cellular component |
extracellular exosome | Orthology | cellular component |
extracellular region | Orthology | cellular component |
extracellular space | Orthology | cellular component |
axonogenesis | Orthology | biological process |
central nervous system development | Orthology | biological process |
brain development | Orthology | biological process |
cytokine-mediated signaling pathway | Orthology | biological process |
intrinsic component of plasma membrane | Orthology | cellular component |
transmembrane signaling receptor activity | Orthology | molecular function |
animal organ development | Orthology | biological process |
immune system process | Orthology | biological process |
cell differentiation | Orthology | biological process |
cell surface receptor signaling pathway | Orthology | biological process |
nervous system process | Orthology | biological process |
cell migration | Orthology | biological process |
neurogenesis | Orthology | biological process |
regulation of cell proliferation | Orthology | biological process |
cell development | Orthology | biological process |
generation of neurons | Orthology | biological process |
extracellular region part | Orthology | cellular component |
enzyme binding | Blast | molecular function |
molecular function regulator | Blast | molecular function |
cell junction | Blast | cellular component |
adherens junction | Blast | cellular component |
macromolecular complex | Blast | cellular component |
cell adhesion molecule binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
phosphoprotein phosphatase activity | Hs | molecular function | 227 | 2.16e-65 |
protein tyrosine phosphatase activity | Hs | molecular function | 227 | 2.16e-65 |
transmembrane receptor protein tyrosine phosphatase activity | Hs | molecular function | 227 | 2.16e-65 |
Ras guanyl-nucleotide exchange factor activity | Hs | molecular function | 227 | 2.16e-65 |
protein binding | Hs | molecular function | 227 | 2.16e-65 |
intracellular | Hs | cellular component | 227 | 2.16e-65 |
nucleus | Hs | cellular component | 199 | 7.63e-56 |
cytoplasm | Hs | cellular component | 199 | 7.63e-56 |
plasma membrane | Hs | cellular component | 227 | 2.16e-65 |
integral component of plasma membrane | Hs | cellular component | 227 | 2.16e-65 |
cell-cell junction | Hs | cellular component | 199 | 2.43e-54 |
cell-cell adherens junction | Hs | cellular component | 199 | 2.43e-54 |
membrane | Hs | cellular component | 227 | 2.16e-65 |
integral component of membrane | Hs | cellular component | 227 | 2.16e-65 |
hydrolase activity | Hs | molecular function | 227 | 2.16e-65 |
phosphatase activity | Hs | molecular function | 227 | 2.16e-65 |
lamellipodium | Hs | cellular component | 199 | 2.43e-54 |
identical protein binding | Hs | molecular function | 227 | 2.16e-65 |
receptor complex | Hs | cellular component | 227 | 2.16e-65 |
cadherin binding | Hs | molecular function | 199 | 2.43e-54 |
perinuclear region of cytoplasm | Hs | cellular component | 199 | 2.43e-54 |
extracellular exosome | Hs | cellular component | 227 | 2.16e-65 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein tyrosine phosphatase activity | SMART | molecular function | 7.0E-91 |
protein dephosphorylation | SMART | biological process | 7.0E-91 |
dephosphorylation | ProSiteProfiles | biological process | 10.954 |
phosphatase activity | ProSiteProfiles | molecular function | 10.954 |