Gene Card
Best human hits
HMGB1; HMGB2; HMGB3
Species
Unique Gene ID
Phfumi.g00006794
Gene Model ID
Phfumi.CG.MTP2014.S5204.g06794
Location
S5204:9337..10307
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
HMG_box_dom | SMART | High mobility group box domain |
HMG_box_dom_sf | Gene3D | High mobility group box domain superfamily |
HMG_box_dom_sf | SUPERFAMILY | High mobility group box domain superfamily |
HMG_box_dom | ProSiteProfiles | High mobility group box domain |
HMG_box_dom | Pfam | High mobility group box domain |
GO Term | Annotation Origin | Type |
---|---|---|
DNA binding | Blast | molecular function |
double-stranded DNA binding | Blast | molecular function |
transcription factor activity, sequence-specific DNA binding | Blast | molecular function |
RNA binding | Blast | molecular function |
integrin binding | Blast | molecular function |
protein binding | Blast | molecular function |
extracellular region | Blast | cellular component |
extracellular space | Blast | cellular component |
cell | Blast | cellular component |
nucleus | Blast | cellular component |
nucleoplasm | Blast | cellular component |
nucleolus | Blast | cellular component |
cytoplasm | Blast | cellular component |
endosome | Blast | cellular component |
early endosome | Blast | cellular component |
plasma membrane | Blast | cellular component |
chemotaxis | Blast | biological process |
transcription factor binding | Blast | molecular function |
cell surface | Blast | cellular component |
membrane | Blast | cellular component |
macromolecular complex | Blast | cellular component |
neuron projection | Blast | cellular component |
transcription regulatory region DNA binding | Blast | molecular function |
perinuclear region of cytoplasm | Blast | cellular component |
intracellular non-membrane-bounded organelle | Blast | cellular component |
nuclear lumen | Blast | cellular component |
transcription regulatory region sequence-specific DNA binding | Blast | molecular function |
carbohydrate derivative binding | Blast | molecular function |
anion binding | Blast | molecular function |
receptor binding | Blast | molecular function |
molecular function regulator | Blast | molecular function |
regulation of signal transduction | Blast | biological process |
signaling receptor activity | Blast | molecular function |
cytoplasmic part | Blast | cellular component |
intracellular membrane-bounded organelle | Blast | cellular component |
binding | Blast | molecular function |
protein kinase binding | Blast | molecular function |
protein kinase activity | Blast | molecular function |
regulation of cellular metabolic process | Blast | biological process |
enzyme regulator activity | Blast | molecular function |
catalytic activity | Blast | molecular function |
enzyme activator activity | Blast | molecular function |
intracellular organelle part | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
endomembrane system | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
plasma membrane part | Blast | cellular component |
enzyme binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
four-way junction DNA binding | Hs | molecular function | 176 | 2.94e-56 |
bubble DNA binding | Hs | molecular function | 176 | 2.94e-56 |
nuclear chromatin | Hs | cellular component | 168 | 5.04e-53 |
condensed chromosome | Hs | cellular component | 176 | 2.94e-56 |
enhancer sequence-specific DNA binding | Hs | molecular function | 168 | 5.04e-53 |
lipopolysaccharide binding | Hs | molecular function | 176 | 2.94e-56 |
phosphatidylserine binding | Hs | molecular function | 176 | 2.94e-56 |
DNA binding | Hs | molecular function | 176 | 2.94e-56 |
damaged DNA binding | Hs | molecular function | 176 | 2.94e-56 |
double-stranded DNA binding | Hs | molecular function | 176 | 2.94e-56 |
single-stranded DNA binding | Hs | molecular function | 176 | 2.94e-56 |
transcription factor activity, sequence-specific DNA binding | Hs | molecular function | 176 | 2.94e-56 |
RNA binding | Hs | molecular function | 176 | 2.94e-56 |
double-stranded RNA binding | Hs | molecular function | 176 | 2.94e-56 |
single-stranded RNA binding | Hs | molecular function | 176 | 2.94e-56 |
cytokine activity | Hs | molecular function | 176 | 2.94e-56 |
integrin binding | Hs | molecular function | 176 | 2.94e-56 |
protein binding | Hs | molecular function | 176 | 2.94e-56 |
extracellular region | Hs | cellular component | 176 | 2.94e-56 |
extracellular space | Hs | cellular component | 176 | 2.94e-56 |
cell | Hs | cellular component | 168 | 5.04e-53 |
nucleus | Hs | cellular component | 176 | 2.94e-56 |
nucleoplasm | Hs | cellular component | 176 | 2.94e-56 |
chromosome | Hs | cellular component | 176 | 2.94e-56 |
nucleolus | Hs | cellular component | 168 | 5.04e-53 |
cytoplasm | Hs | cellular component | 176 | 2.94e-56 |
endosome | Hs | cellular component | 176 | 2.94e-56 |
early endosome | Hs | cellular component | 176 | 2.94e-56 |
endoplasmic reticulum-Golgi intermediate compartment | Hs | cellular component | 176 | 2.94e-56 |
plasma membrane | Hs | cellular component | 176 | 2.94e-56 |
transcription factor binding | Hs | molecular function | 176 | 2.94e-56 |
drug binding | Hs | molecular function | 168 | 5.04e-53 |
DNA binding, bending | Hs | molecular function | 176 | 2.94e-56 |
cell surface | Hs | cellular component | 176 | 2.94e-56 |
calcium-dependent protein kinase regulator activity | Hs | molecular function | 176 | 2.94e-56 |
membrane | Hs | cellular component | 176 | 2.94e-56 |
lyase activity | Hs | molecular function | 176 | 2.94e-56 |
transcriptional repressor complex | Hs | cellular component | 176 | 2.94e-56 |
protein domain specific binding | Hs | molecular function | 168 | 5.04e-53 |
C-X-C chemokine binding | Hs | molecular function | 176 | 2.94e-56 |
protein kinase activator activity | Hs | molecular function | 176 | 2.94e-56 |
macromolecular complex | Hs | cellular component | 168 | 5.04e-53 |
secretory granule lumen | Hs | cellular component | 176 | 2.94e-56 |
alphav-beta3 integrin-HMGB1 complex | Hs | cellular component | 176 | 2.94e-56 |
chemoattractant activity | Hs | molecular function | 176 | 2.94e-56 |
neuron projection | Hs | cellular component | 176 | 2.94e-56 |
transcription regulatory region DNA binding | Hs | molecular function | 168 | 5.04e-53 |
non-sequence-specific DNA binding, bending | Hs | molecular function | 168 | 5.04e-53 |
perinuclear region of cytoplasm | Hs | cellular component | 168 | 5.04e-53 |
RAGE receptor binding | Hs | molecular function | 176 | 2.94e-56 |
DNA polymerase binding | Hs | molecular function | 176 | 2.94e-56 |
repressing transcription factor binding | Hs | molecular function | 176 | 2.94e-56 |
supercoiled DNA binding | Hs | molecular function | 176 | 2.94e-56 |
ficolin-1-rich granule lumen | Hs | cellular component | 176 | 2.94e-56 |
GO Term | Analysis | Type | e-value |
---|