Gene Card
Best human hits
D2HGDH; DHCR24; LDHD
Species
Unique Gene ID
Phfumi.g00002345
Gene Model ID
Phfumi.CG.MTP2014.S575.g02345
Location
S575:30042..33014
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
7 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Oxid_FAD_bind_N | Pfam | FAD linked oxidase, N-terminal |
| FAD-bd_2 | ProSiteProfiles | FAD-binding, type 2 |
| ALO | Pfam | D-arabinono-1,4-lactone oxidase |
| FAD_lactone_oxidase | PANTHER | L-gulonolactone/D-arabinono-1,4-lactone oxidase |
| FAD_lactone_oxidase | PIRSF | L-gulonolactone/D-arabinono-1,4-lactone oxidase |
| FAD-bd_2_sub1 | Gene3D | FAD-binding, type 2, subdomain 1 |
| FAD-bd_2-like_sf | SUPERFAMILY | FAD-binding, type 2-like superfamily |
GOSlim
19 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| Golgi membrane | Blast | cellular component |
| catalytic activity | Blast | molecular function |
| protein binding | Blast | molecular function |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| mitochondrion | Blast | cellular component |
| mitochondrial inner membrane | Blast | cellular component |
| mitochondrial matrix | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| endoplasmic reticulum membrane | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Blast | cellular component |
| cytoskeleton | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| enzyme binding | Blast | molecular function |
| flavin adenine dinucleotide binding | Blast | molecular function |
| oxidation-reduction process | Blast | biological process |
| binding | Blast | molecular function |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
26 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 52.8 | 8.87e-08 |
| delta24(24-1) sterol reductase activity | Hs | molecular function | 52.8 | 8.87e-08 |
| catalytic activity | Hs | molecular function | 57.0 | 3.57e-09 |
| D-lactate dehydrogenase (cytochrome) activity | Hs | molecular function | 57.0 | 3.57e-09 |
| protein binding | Hs | molecular function | 41.6 | 3.46e-04 |
| nucleus | Hs | cellular component | 52.8 | 8.87e-08 |
| cytoplasm | Hs | cellular component | 52.8 | 8.87e-08 |
| mitochondrion | Hs | cellular component | 57.0 | 3.57e-09 |
| mitochondrial inner membrane | Hs | cellular component | 41.6 | 3.46e-04 |
| mitochondrial matrix | Hs | cellular component | 57.0 | 3.57e-09 |
| endoplasmic reticulum | Hs | cellular component | 52.8 | 8.87e-08 |
| endoplasmic reticulum membrane | Hs | cellular component | 52.8 | 8.87e-08 |
| Golgi apparatus | Hs | cellular component | 52.8 | 8.87e-08 |
| cytosol | Hs | cellular component | 52.8 | 8.87e-08 |
| cytoskeleton | Hs | cellular component | 52.8 | 8.87e-08 |
| membrane | Hs | cellular component | 52.8 | 8.87e-08 |
| integral component of membrane | Hs | cellular component | 52.8 | 8.87e-08 |
| oxidoreductase activity | Hs | molecular function | 57.0 | 3.57e-09 |
| oxidoreductase activity, acting on CH-OH group of donors | Hs | molecular function | 57.0 | 3.57e-09 |
| oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | Hs | molecular function | 52.8 | 8.87e-08 |
| enzyme binding | Hs | molecular function | 52.8 | 8.87e-08 |
| peptide antigen binding | Hs | molecular function | 52.8 | 8.87e-08 |
| delta24-sterol reductase activity | Hs | molecular function | 52.8 | 8.87e-08 |
| flavin adenine dinucleotide binding | Hs | molecular function | 57.0 | 3.57e-09 |
| (R)-2-hydroxyglutarate dehydrogenase activity | Hs | molecular function | 57.0 | 3.57e-09 |
| FAD binding | Hs | molecular function | 57.0 | 3.57e-09 |
GO (InterProScan)
9 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| catalytic activity | Gene3D | molecular function | 1.8E-18 |
| membrane | Pfam | cellular component | 1.2E-21 |
| oxidoreductase activity | Pfam | molecular function | 3.6E-25 |
| oxidoreductase activity, acting on CH-OH group of donors | SUPERFAMILY | molecular function | 1.26E-40 |
| flavin adenine dinucleotide binding | SUPERFAMILY | molecular function | 1.26E-40 |
| oxidation-reduction process | PIRSF | biological process | 9.2E-94 |
| FAD binding | ProSiteProfiles | molecular function | 18.447 |
| D-arabinono-1,4-lactone oxidase activity | Pfam | molecular function | 1.2E-21 |
| oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor | PIRSF | molecular function | 9.2E-94 |
