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  4. Gene 'Phmamm.CG.MTP2014.S2...' > 

Gene Card

Best human hits

SMAD2; SMAD3; SMAD4

Species

P.fumigata

Unique Gene ID

Phfumi.g00002881

Gene Model ID

Phfumi.CG.MTP2014.S869.g02881

Location

S869:20451..26293

Transcript Models and Sequences

  Phfumi.CG.MTP2014.S869.g02881.01.t
Phfumi.CG.MTP2014.S869.g02881.02.t

External Database Gene Card

External database links

No result

Collections
WashU Genome Browser

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Genomicus Synteny Browser

Genomicus browser link

Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

10 results

IPR Term Analysis Definition
SMAD_dom_Dwarfin-type ProSiteProfiles SMAD domain, Dwarfin-type
SMAD_dom_Dwarfin-type Pfam SMAD domain, Dwarfin-type
MAD_homology_MH1 ProSiteProfiles MAD homology, MH1
SMAD_FHA_dom_sf SUPERFAMILY SMAD/FHA domain superfamily
MAD_homology1_Dwarfin-type Pfam MAD homology 1, Dwarfin-type
Dwarfin PANTHER Dwarfin
SMAD_dom_Dwarfin-type SMART SMAD domain, Dwarfin-type
SMAD_MH1_sf SUPERFAMILY SMAD MH1 domain superfamily
SMAD-like_dom_sf Gene3D SMAD-like domain superfamily
SMAD_MH1_sf Gene3D SMAD MH1 domain superfamily

GOSlim

82 results

GO Term Annotation Origin Type
negative regulation of transcription from RNA polymerase II promoter Orthology biological process
RNA polymerase II regulatory region sequence-specific DNA binding Orthology molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Orthology molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Orthology molecular function
core promoter proximal region sequence-specific DNA binding Orthology molecular function
transcription factor activity, transcription factor binding Orthology molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Orthology molecular function
response to hypoxia Orthology biological process
DNA binding Orthology molecular function
chromatin binding Orthology molecular function
double-stranded DNA binding Blast molecular function
transcription factor activity, sequence-specific DNA binding Orthology molecular function
protein binding Orthology molecular function
intracellular Orthology cellular component
nucleus Orthology cellular component
nucleoplasm Orthology cellular component
cytoplasm Orthology cellular component
centrosome Orthology cellular component
cytosol Orthology cellular component
plasma membrane Blast cellular component
transcription, DNA-templated Orthology biological process
regulation of transcription, DNA-templated Orthology biological process
regulation of transcription from RNA polymerase II promoter Orthology biological process
protein phosphorylation Orthology biological process
spermatogenesis Orthology biological process
axon guidance Orthology biological process
heart development Orthology biological process
transcription factor binding Orthology molecular function
zinc ion binding Blast molecular function
cell proliferation Orthology biological process
negative regulation of cell proliferation Orthology biological process
membrane Blast cellular component
integral component of membrane Blast cellular component
enzyme binding Blast molecular function
protein kinase binding Blast molecular function
ubiquitin protein ligase binding Blast molecular function
macromolecular complex Orthology cellular component
intracellular signal transduction Orthology biological process
regulation of cell proliferation Orthology biological process
identical protein binding Orthology molecular function
protein homodimerization activity Orthology molecular function
sequence-specific DNA binding Orthology molecular function
transcription regulatory region DNA binding Orthology molecular function
negative regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription, DNA-templated Orthology biological process
positive regulation of transcription from RNA polymerase II promoter Orthology biological process
metal ion binding Orthology molecular function
protein heterodimerization activity Orthology molecular function
negative regulation of cell death Orthology biological process
intracellular non-membrane-bounded organelle Orthology cellular component
nuclear lumen Orthology cellular component
reproductive process Orthology biological process
animal organ development Orthology biological process
anatomical structure morphogenesis Orthology biological process
anatomical structure formation involved in morphogenesis Orthology biological process
multicellular organism development Orthology biological process
macromolecular complex binding Orthology molecular function
intracellular part Orthology cellular component
cellular process Orthology biological process
cell Orthology cellular component
cell surface receptor signaling pathway Orthology biological process
cellular response to organic substance Orthology biological process
sexual reproduction Orthology biological process
anatomical structure development Orthology biological process
cell differentiation Orthology biological process
positive regulation of signal transduction Orthology biological process
peptidase activity, acting on L-amino acid peptides Orthology molecular function
regulation of signal transduction Orthology biological process
cellular component organization Orthology biological process
molecular transducer activity Orthology molecular function
nuclear part Orthology cellular component
developmental process Orthology biological process
anion binding Orthology molecular function
neuron differentiation Orthology biological process
organelle organization Orthology biological process
cellular protein modification process Orthology biological process
protein homooligomerization Orthology biological process
negative regulation of signal transduction Orthology biological process
receptor binding Blast molecular function
organelle inner membrane Blast cellular component
nuclear membrane Blast cellular component
RNA binding Blast molecular function

GO (Orthology)

87 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type
negative regulation of transcription from RNA polymerase II promoter Hs biological process
nuclear chromatin Hs cellular component
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function
core promoter proximal region sequence-specific DNA binding Hs molecular function
transcription factor activity, transcription factor binding Hs molecular function
transcription factor activity, RNA polymerase II transcription factor binding Hs molecular function
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function
RNA polymerase II transcription factor binding Hs molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function
ovarian follicle development Hs biological process
branching involved in ureteric bud morphogenesis Hs biological process
response to hypoxia Hs biological process
gastrulation with mouth forming second Hs biological process
kidney development Hs biological process
atrioventricular valve formation Hs biological process
DNA binding Hs molecular function
chromatin binding Hs molecular function
transcription factor activity, sequence-specific DNA binding Hs molecular function
protein binding Hs molecular function
collagen binding Hs molecular function
intracellular Hs cellular component
nucleus Hs cellular component
nucleoplasm Hs cellular component
transcription factor complex Hs cellular component
cytoplasm Hs cellular component
centrosome Hs cellular component
cytosol Hs cellular component
transcription, DNA-templated Hs biological process
regulation of transcription, DNA-templated Hs biological process
regulation of transcription from RNA polymerase II promoter Hs biological process
cellular iron ion homeostasis Hs biological process
transforming growth factor beta receptor signaling pathway Hs biological process
spermatogenesis Hs biological process
single fertilization Hs biological process
gastrulation Hs biological process
axon guidance Hs biological process
endoderm development Hs biological process
mesoderm development Hs biological process
cell proliferation Hs biological process
negative regulation of cell proliferation Hs biological process
male gonad development Hs biological process
female gonad development Hs biological process
anterior/posterior pattern specification Hs biological process
positive regulation of epithelial to mesenchymal transition Hs biological process
positive regulation of pathway-restricted SMAD protein phosphorylation Hs biological process
neural crest cell differentiation Hs biological process
protein deubiquitination Hs biological process
regulation of transforming growth factor beta receptor signaling pathway Hs biological process
negative regulation of cell growth Hs biological process
BMP signaling pathway Hs biological process
positive regulation of transforming growth factor beta receptor signaling pathway Hs biological process
positive regulation of BMP signaling pathway Hs biological process
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Hs molecular function
activin responsive factor complex Hs cellular component
somite rostral/caudal axis specification Hs biological process
somatic stem cell population maintenance Hs biological process
intracellular signal transduction Hs biological process
atrioventricular canal development Hs biological process
regulation of cell proliferation Hs biological process
identical protein binding Hs molecular function
protein homodimerization activity Hs molecular function
sulfate binding Hs molecular function
sequence-specific DNA binding Hs molecular function
transcription regulatory region DNA binding Hs molecular function
negative regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription, DNA-templated Hs biological process
positive regulation of transcription from RNA polymerase II promoter Hs biological process
metal ion binding Hs molecular function
protein heterodimerization activity Hs molecular function
developmental growth Hs biological process
neuron fate commitment Hs biological process
tissue morphogenesis Hs biological process
formation of anatomical boundary Hs biological process
positive regulation of histone H3-K4 methylation Hs biological process
palate development Hs biological process
uterus development Hs biological process
SMAD protein signal transduction Hs biological process
negative regulation of cell death Hs biological process
endocardial cell differentiation Hs biological process
protein homotrimerization Hs biological process
negative regulation of ERK1 and ERK2 cascade Hs biological process
I-SMAD binding Hs molecular function
R-SMAD binding Hs molecular function
SMAD protein complex Hs cellular component
RNA polymerase II transcription factor complex Hs cellular component

GO (Blast)

67 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae		 Type Score E-value
nuclear chromatin Hs cellular component 486 8.99e-170
RNA polymerase II regulatory region sequence-specific DNA binding Hs molecular function 486 8.99e-170
RNA polymerase II core promoter proximal region sequence-specific DNA binding Hs molecular function 486 8.99e-170
RNA polymerase II transcription factor activity, sequence-specific DNA binding Hs molecular function 486 8.99e-170
transcription factor activity, RNA polymerase II core promoter sequence-specific Hs molecular function 195 4.26e-58
core promoter proximal region sequence-specific DNA binding Hs molecular function 486 8.99e-170
transcription factor activity, transcription factor binding Hs molecular function 486 8.99e-170
transcription factor activity, RNA polymerase II transcription factor binding Hs molecular function 486 8.99e-170
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding Hs molecular function 486 8.99e-170
RNA polymerase II transcription factor binding Hs molecular function 486 8.99e-170
RNA polymerase II activating transcription factor binding Hs molecular function 195 4.26e-58
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding Hs molecular function 486 8.99e-170
DNA binding Hs molecular function 486 8.99e-170
chromatin binding Hs molecular function 486 8.99e-170
double-stranded DNA binding Hs molecular function 195 4.26e-58
transcription factor activity, sequence-specific DNA binding Hs molecular function 486 8.99e-170
transforming growth factor beta receptor binding Hs molecular function 195 4.26e-58
protein binding Hs molecular function 486 8.99e-170
collagen binding Hs molecular function 486 8.99e-170
intracellular Hs cellular component 486 8.99e-170
nucleus Hs cellular component 486 8.99e-170
nuclear inner membrane Hs cellular component 195 4.26e-58
nucleoplasm Hs cellular component 486 8.99e-170
transcription factor complex Hs cellular component 486 8.99e-170
cytoplasm Hs cellular component 486 8.99e-170
centrosome Hs cellular component 486 8.99e-170
cytosol Hs cellular component 486 8.99e-170
plasma membrane Hs cellular component 195 4.26e-58
beta-catenin binding Hs molecular function 195 4.26e-58
transcription factor binding Hs molecular function 195 4.26e-58
zinc ion binding Hs molecular function 195 4.26e-58
membrane Hs cellular component 193 9.50e-57
integral component of membrane Hs cellular component 193 9.50e-57
DEAD/H-box RNA helicase binding Hs molecular function 195 4.26e-58
enzyme binding Hs molecular function 195 4.26e-58
protein kinase binding Hs molecular function 195 4.26e-58
phosphatase binding Hs molecular function 195 4.26e-58
transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Hs molecular function 486 8.99e-170
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Hs molecular function 195 4.26e-58
chromatin DNA binding Hs molecular function 195 4.26e-58
ubiquitin protein ligase binding Hs molecular function 195 4.26e-58
mineralocorticoid receptor binding Hs molecular function 195 4.26e-58
activin responsive factor complex Hs cellular component 486 8.99e-170
macromolecular complex Hs cellular component 193 9.50e-57
activating transcription factor binding Hs molecular function 193 9.50e-57
type I transforming growth factor beta receptor binding Hs molecular function 193 9.50e-57
glucocorticoid receptor binding Hs molecular function 195 4.26e-58
enhancer binding Hs molecular function 195 4.26e-58
identical protein binding Hs molecular function 486 8.99e-170
protein homodimerization activity Hs molecular function 486 8.99e-170
ubiquitin binding Hs molecular function 195 4.26e-58
sulfate binding Hs molecular function 486 8.99e-170
receptor complex Hs cellular component 195 4.26e-58
bHLH transcription factor binding Hs molecular function 195 4.26e-58
sequence-specific DNA binding Hs molecular function 486 8.99e-170
transcription regulatory region DNA binding Hs molecular function 486 8.99e-170
SMAD binding Hs molecular function 195 4.26e-58
metal ion binding Hs molecular function 486 8.99e-170
protein heterodimerization activity Hs molecular function 486 8.99e-170
co-SMAD binding Hs molecular function 195 4.26e-58
I-SMAD binding Hs molecular function 486 8.99e-170
R-SMAD binding Hs molecular function 486 8.99e-170
primary miRNA binding Hs molecular function 195 4.26e-58
SMAD protein complex Hs cellular component 486 8.99e-170
SMAD2-SMAD3 protein complex Hs cellular component 195 4.26e-58
RNA polymerase II transcription factor complex Hs cellular component 486 8.99e-170
disordered domain specific binding Hs molecular function 193 9.50e-57

GO (InterProScan)

6 results

GO Term Analysis Type e-value
transcription factor activity, sequence-specific DNA binding ProSiteProfiles molecular function 19.741
protein binding SUPERFAMILY molecular function 2.73E-83
intracellular PANTHER cellular component 8.7E-173
transcription factor complex ProSiteProfiles cellular component 19.741
regulation of transcription, DNA-templated PANTHER biological process 8.7E-173
transforming growth factor beta receptor signaling pathway Gene3D biological process 4.8E-20

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