IPR Term	Analysis	Definition
TPR/MLP1	Pfam	Nucleoprotein TPR/MLP1

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
nucleotide binding	Blast	molecular function
chromatin binding	Orthology	molecular function
RNA binding	Orthology	molecular function
protein kinase activity	Blast	molecular function
protein serine/threonine kinase activity	Blast	molecular function
structural molecule activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Blast	molecular function
intracellular	Blast	cellular component
nucleus	Orthology	cellular component
nuclear envelope	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Blast	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Blast	cellular component
cell cycle	Orthology	biological process
protein transport	Orthology	biological process
tubulin binding	Orthology	molecular function
membrane	Orthology	cellular component
kinase activity	Orthology	molecular function
basolateral plasma membrane	Blast	cellular component
transferase activity	Blast	molecular function
cell junction	Blast	cellular component
midbody	Blast	cellular component
nuclear membrane	Orthology	cellular component
protein homodimerization activity	Orthology	molecular function
neuronal cell body	Blast	cellular component
metal ion binding	Blast	molecular function
cell adhesion molecule binding	Blast	molecular function
cell division	Orthology	biological process
extracellular exosome	Blast	cellular component
intracellular organelle part	Orthology	cellular component
intracellular non-membrane-bounded organelle	Orthology	cellular component
macromolecular complex	Orthology	cellular component
cytoskeletal part	Orthology	cellular component
microtubule cytoskeleton	Orthology	cellular component
oxidation-reduction process	Orthology	biological process
organic substance transport	Orthology	biological process
intracellular transport	Orthology	biological process
intracellular protein transport	Orthology	biological process
gene expression	Orthology	biological process
establishment of protein localization to organelle	Orthology	biological process
organelle organization	Orthology	biological process
mitotic cell cycle phase transition	Orthology	biological process
protein modification by small protein conjugation	Orthology	biological process
membrane part	Orthology	cellular component
DNA binding	Orthology	molecular function
cellular response to stress	Orthology	biological process
nuclear lumen	Orthology	cellular component
nuclear part	Orthology	cellular component
negative regulation of gene expression	Orthology	biological process
translational initiation	Orthology	biological process
protein kinase binding	Orthology	molecular function
macromolecular complex binding	Orthology	molecular function
microtubule-based process	Orthology	biological process
adherens junction	Blast	cellular component
enzyme binding	Blast	molecular function
anchoring junction	Blast	cellular component
Golgi apparatus part	Blast	cellular component
plasma membrane region	Blast	cellular component
cell adhesion	Blast	biological process
signaling	Blast	biological process
cell communication	Blast	biological process
whole membrane	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
endomembrane system	Blast	cellular component
bounding membrane of organelle	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
chromosome, centromeric region	Hs	cellular component
kinetochore	Hs	cellular component
chromatin binding	Hs	molecular function
RNA binding	Hs	molecular function
mRNA binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nuclear envelope	Hs	cellular component
nuclear pore	Hs	cellular component
nucleoplasm	Hs	cellular component
chromosome	Hs	cellular component
cytoplasm	Hs	cellular component
spindle	Hs	cellular component
cytoskeleton	Hs	cellular component
cytoplasmic dynein complex	Hs	cellular component
regulation of glycolytic process	Hs	biological process
RNA import into nucleus	Hs	biological process
RNA export from nucleus	Hs	biological process
mRNA export from nucleus	Hs	biological process
tRNA export from nucleus	Hs	biological process
protein import into nucleus	Hs	biological process
nuclear pore organization	Hs	biological process
cell cycle	Hs	biological process
mitotic spindle assembly checkpoint	Hs	biological process
regulation of mitotic sister chromatid separation	Hs	biological process
protein transport	Hs	biological process
tubulin binding	Hs	molecular function
membrane	Hs	cellular component
viral process	Hs	biological process
protein sumoylation	Hs	biological process
structural constituent of nuclear pore	Hs	molecular function
extrinsic component of membrane	Hs	cellular component
heat shock protein binding	Hs	molecular function
positive regulation of heterochromatin assembly	Hs	biological process
nuclear membrane	Hs	cellular component
mRNA export from nucleus in response to heat stress	Hs	biological process
nuclear periphery	Hs	cellular component
cellular response to heat	Hs	biological process
positive regulation of protein import into nucleus	Hs	biological process
nuclear inclusion body	Hs	cellular component
protein homodimerization activity	Hs	molecular function
host cell	Hs	cellular component
nuclear pore nuclear basket	Hs	cellular component
negative regulation of translational initiation	Hs	biological process
positive regulation of protein export from nucleus	Hs	biological process
mitogen-activated protein kinase binding	Hs	molecular function
mRNA transport	Hs	biological process
cell division	Hs	biological process
regulation of gene silencing by miRNA	Hs	biological process
dynein complex binding	Hs	molecular function
mitotic spindle	Hs	cellular component
positive regulation of mitotic cell cycle spindle assembly checkpoint	Hs	biological process
positive regulation of intracellular protein transport	Hs	biological process
regulation of mitotic spindle assembly	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	44.3	0.001
chromosome, centromeric region	Hs	cellular component	701	0.0
kinetochore	Hs	cellular component	701	0.0
cornified envelope	Hs	cellular component	42.4	0.004
chromatin binding	Hs	molecular function	701	0.0
RNA binding	Hs	molecular function	701	0.0
mRNA binding	Hs	molecular function	701	0.0
protein kinase activity	Hs	molecular function	44.3	0.001
protein serine/threonine kinase activity	Hs	molecular function	44.3	0.001
protein kinase C binding	Hs	molecular function	42.4	0.004
structural molecule activity	Hs	molecular function	42.4	0.004
structural constituent of cytoskeleton	Hs	molecular function	42.4	0.004
protein binding	Hs	molecular function	701	0.0
ATP binding	Hs	molecular function	44.3	0.001
intracellular	Hs	cellular component	44.3	0.001
nucleus	Hs	cellular component	701	0.0
nuclear envelope	Hs	cellular component	701	0.0
nuclear pore	Hs	cellular component	701	0.0
nucleoplasm	Hs	cellular component	701	0.0
chromosome	Hs	cellular component	701	0.0
cytoplasm	Hs	cellular component	701	0.0
spindle	Hs	cellular component	701	0.0
cytosol	Hs	cellular component	44.3	0.001
cytoskeleton	Hs	cellular component	701	0.0
cytoplasmic dynein complex	Hs	cellular component	701	0.0
intermediate filament	Hs	cellular component	42.4	0.004
plasma membrane	Hs	cellular component	44.3	0.001
cell-cell junction	Hs	cellular component	42.4	0.004
fascia adherens	Hs	cellular component	42.4	0.004
intercalated disc	Hs	cellular component	42.4	0.004
tubulin binding	Hs	molecular function	701	0.0
membrane	Hs	cellular component	701	0.0
kinase activity	Hs	molecular function	44.3	0.001
basolateral plasma membrane	Hs	cellular component	42.4	0.004
transferase activity	Hs	molecular function	44.3	0.001
Rho GTPase binding	Hs	molecular function	44.3	0.001
structural constituent of nuclear pore	Hs	molecular function	701	0.0
SH3 domain binding	Hs	molecular function	44.3	0.001
extrinsic component of membrane	Hs	cellular component	701	0.0
cell junction	Hs	cellular component	42.4	0.004
desmosome	Hs	cellular component	42.4	0.004
PDZ domain binding	Hs	molecular function	44.3	0.001
midbody	Hs	cellular component	44.3	0.001
protein binding, bridging	Hs	molecular function	42.4	0.004
heat shock protein binding	Hs	molecular function	701	0.0
nuclear membrane	Hs	cellular component	701	0.0
Golgi cisterna	Hs	cellular component	44.3	0.001
cleavage furrow	Hs	cellular component	44.3	0.001
nuclear periphery	Hs	cellular component	701	0.0
nuclear inclusion body	Hs	cellular component	701	0.0
protein homodimerization activity	Hs	molecular function	701	0.0
neuronal cell body	Hs	cellular component	44.3	0.001
host cell	Hs	cellular component	701	0.0
nuclear pore nuclear basket	Hs	cellular component	701	0.0
metal ion binding	Hs	molecular function	44.3	0.001
cell adhesion molecule binding	Hs	molecular function	42.4	0.004
mitogen-activated protein kinase binding	Hs	molecular function	701	0.0
extracellular exosome	Hs	cellular component	42.4	0.004
dynein complex binding	Hs	molecular function	701	0.0
mitotic spindle	Hs	cellular component	701	0.0
cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	Hs	molecular function	42.4	0.004
scaffold protein binding	Hs	molecular function	44.3	0.001
ficolin-1-rich granule membrane	Hs	cellular component	42.4	0.004

GO Term	Analysis	Type	e-value
protein import into nucleus	Pfam	biological process	7.9E-25