IPR Term	Analysis	Definition
Nucleotide_cyclase	Gene3D	Nucleotide cyclase
Nucleotide_cyclase	SUPERFAMILY	Nucleotide cyclase
Adcy	PIRSF	Adenylate cyclase
A/G_cyclase	SMART	Adenylyl cyclase class-3/4/guanylyl cyclase
A/G_cyclase	ProSiteProfiles	Adenylyl cyclase class-3/4/guanylyl cyclase
AC_N	Pfam	Adenylate cyclase, N-terminal
Adcy_conserved_dom	Pfam	Adenylate cyclase, conserved domain
A/G_cyclase	Pfam	Adenylyl cyclase class-3/4/guanylyl cyclase
A/G_cyclase_CS	ProSitePatterns	Adenylyl cyclase class-4/guanylyl cyclase, conserved site

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
intracellular	Orthology	cellular component
plasma membrane	Orthology	cellular component
G-protein coupled receptor signaling pathway	Orthology	biological process
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
protein kinase binding	Orthology	molecular function
intrinsic component of plasma membrane	Orthology	cellular component
intracellular signal transduction	Orthology	biological process
cell projection	Orthology	cellular component
metal ion binding	Orthology	molecular function
protein heterodimerization activity	Orthology	molecular function
cell surface receptor signaling pathway	Orthology	biological process
catalytic activity	Orthology	molecular function
phosphate-containing compound metabolic process	Orthology	biological process
organelle	Orthology	cellular component
plasma membrane region	Orthology	cellular component
macromolecular complex	Orthology	cellular component
regulation of catalytic activity	Orthology	biological process
regulation of signal transduction	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
cellular process	Orthology	biological process
cell	Orthology	cellular component
cytosol	Orthology	cellular component
enzyme binding	Orthology	molecular function
neuron projection development	Orthology	biological process
cytoskeleton	Orthology	cellular component
nervous system process	Orthology	biological process
cellular response to organic substance	Orthology	biological process
protein transport	Orthology	biological process
regulation of signaling	Orthology	biological process
cell-cell signaling	Orthology	biological process
response to lipid	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
adenosine receptor signaling pathway	Hs	biological process
renal water homeostasis	Hs	biological process
adenylate cyclase activity	Hs	molecular function
guanylate cyclase activity	Hs	molecular function
protein kinase C binding	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
intracellular	Hs	cellular component
plasma membrane	Hs	cellular component
cilium	Hs	cellular component
cAMP biosynthetic process	Hs	biological process
cGMP biosynthetic process	Hs	biological process
G-protein coupled receptor signaling pathway	Hs	biological process
adenylate cyclase-activating G-protein coupled receptor signaling pathway	Hs	biological process
activation of adenylate cyclase activity	Hs	biological process
adenylate cyclase-activating dopamine receptor signaling pathway	Hs	biological process
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Hs	biological process
adenylate cyclase-inhibiting dopamine receptor signaling pathway	Hs	biological process
positive regulation of cytosolic calcium ion concentration	Hs	biological process
dopamine receptor signaling pathway	Hs	biological process
locomotory behavior	Hs	biological process
guanylate cyclase complex, soluble	Hs	cellular component
adenylate cyclase binding	Hs	molecular function
cyclic nucleotide biosynthetic process	Hs	biological process
negative regulation of neuron projection development	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
lyase activity	Hs	molecular function
phosphorus-oxygen lyase activity	Hs	molecular function
protein kinase binding	Hs	molecular function
intrinsic component of plasma membrane	Hs	cellular component
intracellular signal transduction	Hs	biological process
cell projection	Hs	cellular component
intermediate filament cytoskeleton	Hs	cellular component
metal ion binding	Hs	molecular function
protein heterodimerization activity	Hs	molecular function
neuromuscular process controlling balance	Hs	biological process
regulation of insulin secretion involved in cellular response to glucose stimulus	Hs	biological process
cellular response to glucagon stimulus	Hs	biological process
cellular response to prostaglandin E stimulus	Hs	biological process
scaffold protein binding	Hs	molecular function
regulation of blood vessel diameter	Hs	biological process
cellular response to forskolin	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	905	0.0
adenylate cyclase activity	Hs	molecular function	905	0.0
guanylate cyclase activity	Hs	molecular function	905	0.0
protein kinase C binding	Hs	molecular function	851	0.0
protein binding	Hs	molecular function	851	0.0
ATP binding	Hs	molecular function	905	0.0
intracellular	Hs	cellular component	905	0.0
plasma membrane	Hs	cellular component	905	0.0
cilium	Hs	cellular component	905	0.0
guanylate cyclase complex, soluble	Hs	cellular component	905	0.0
adenylate cyclase binding	Hs	molecular function	905	0.0
calcium- and calmodulin-responsive adenylate cyclase activity	Hs	molecular function	585	0.0
membrane	Hs	cellular component	905	0.0
integral component of membrane	Hs	cellular component	905	0.0
lyase activity	Hs	molecular function	905	0.0
phosphorus-oxygen lyase activity	Hs	molecular function	905	0.0
protein kinase binding	Hs	molecular function	851	0.0
intrinsic component of plasma membrane	Hs	cellular component	851	0.0
cell projection	Hs	cellular component	905	0.0
intermediate filament cytoskeleton	Hs	cellular component	905	0.0
metal ion binding	Hs	molecular function	905	0.0
protein heterodimerization activity	Hs	molecular function	905	0.0
scaffold protein binding	Hs	molecular function	905	0.0

GO Term	Analysis	Type	e-value
adenylate cyclase activity	PIRSF	molecular function	1.1E-190
plasma membrane	PIRSF	cellular component	1.1E-190
cAMP biosynthetic process	PIRSF	biological process	1.1E-190
cyclic nucleotide biosynthetic process	Pfam	biological process	1.4E-60
phosphorus-oxygen lyase activity	Pfam	molecular function	1.4E-60
intracellular signal transduction	Pfam	biological process	1.4E-60