Gene Card
Best human hits
IARS; IARS2; VARS
Species
Unique Gene ID
Phmamm.g00003227
Gene Model ID
Phmamm.CG.MTP2014.S102.g03227
Location
S102:229114..242803
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
8 results
| IPR Term | Analysis | Definition |
|---|---|---|
| tRNAsynth_Ia_anticodon-bd | SUPERFAMILY | Aminoacyl-tRNA synthetase, class Ia, anticodon-binding |
| Ile-tRNA-ligase | TIGRFAM | Isoleucine-tRNA ligase |
| aa-tRNA-synth_Ia | Pfam | Aminoacyl-tRNA synthetase, class Ia |
| Val/Leu/Ile-tRNA-synth_edit | Gene3D | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
| Val/Leu/Ile-tRNA-synth_edit | SUPERFAMILY | Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain |
| Rossmann-like_a/b/a_fold | Gene3D | Rossmann-like alpha/beta/alpha sandwich fold |
| aa-tRNA-synth_I_CS | ProSitePatterns | Aminoacyl-tRNA synthetase, class I, conserved site |
| Ile-tRNA-ligase | PRINTS | Isoleucine-tRNA ligase |
GOSlim
17 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| nucleotide binding | Orthology | molecular function |
| protein binding | Orthology | molecular function |
| ATP binding | Orthology | molecular function |
| cytoplasm | Orthology | cellular component |
| mitochondrion | Blast | cellular component |
| mitochondrial matrix | Blast | cellular component |
| cytosol | Orthology | cellular component |
| membrane | Orthology | cellular component |
| ligase activity | Orthology | molecular function |
| extracellular exosome | Orthology | cellular component |
| RNA binding | Orthology | molecular function |
| cell differentiation | Orthology | biological process |
| RNA metabolic process | Orthology | biological process |
| hydrolase activity | Orthology | molecular function |
| intracellular part | Orthology | cellular component |
| macromolecular complex | Orthology | cellular component |
| enzyme binding | Orthology | molecular function |
GO (Orthology)
18 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|---|---|
| tRNA binding | Hs | molecular function |
| nucleotide binding | Hs | molecular function |
| osteoblast differentiation | Hs | biological process |
| aminoacyl-tRNA editing activity | Hs | molecular function |
| aminoacyl-tRNA ligase activity | Hs | molecular function |
| isoleucine-tRNA ligase activity | Hs | molecular function |
| protein binding | Hs | molecular function |
| ATP binding | Hs | molecular function |
| cytoplasm | Hs | cellular component |
| cytosol | Hs | cellular component |
| translation | Hs | biological process |
| tRNA aminoacylation for protein translation | Hs | biological process |
| isoleucyl-tRNA aminoacylation | Hs | biological process |
| membrane | Hs | cellular component |
| ligase activity | Hs | molecular function |
| aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component |
| GTPase binding | Hs | molecular function |
| extracellular exosome | Hs | cellular component |
GO (Blast)
17 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| tRNA binding | Hs | molecular function | 1150 | 0.0 |
| nucleotide binding | Hs | molecular function | 1150 | 0.0 |
| aminoacyl-tRNA editing activity | Hs | molecular function | 1150 | 0.0 |
| aminoacyl-tRNA ligase activity | Hs | molecular function | 1150 | 0.0 |
| isoleucine-tRNA ligase activity | Hs | molecular function | 1150 | 0.0 |
| valine-tRNA ligase activity | Hs | molecular function | 134 | 3.48e-32 |
| protein binding | Hs | molecular function | 1150 | 0.0 |
| ATP binding | Hs | molecular function | 1150 | 0.0 |
| cytoplasm | Hs | cellular component | 1150 | 0.0 |
| mitochondrion | Hs | cellular component | 246 | 1.76e-69 |
| mitochondrial matrix | Hs | cellular component | 246 | 1.76e-69 |
| cytosol | Hs | cellular component | 1150 | 0.0 |
| membrane | Hs | cellular component | 1150 | 0.0 |
| ligase activity | Hs | molecular function | 1150 | 0.0 |
| aminoacyl-tRNA synthetase multienzyme complex | Hs | cellular component | 1150 | 0.0 |
| GTPase binding | Hs | molecular function | 1150 | 0.0 |
| extracellular exosome | Hs | cellular component | 1150 | 0.0 |
GO (InterProScan)
8 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| nucleotide binding | TIGRFAM | molecular function | 9.5E-248 |
| aminoacyl-tRNA editing activity | Gene3D | molecular function | 5.5E-232 |
| aminoacyl-tRNA ligase activity | Pfam | molecular function | 1.2E-228 |
| isoleucine-tRNA ligase activity | TIGRFAM | molecular function | 9.5E-248 |
| ATP binding | TIGRFAM | molecular function | 9.5E-248 |
| cytoplasm | TIGRFAM | cellular component | 9.5E-248 |
| tRNA aminoacylation for protein translation | Gene3D | biological process | 5.5E-232 |
| isoleucyl-tRNA aminoacylation | TIGRFAM | biological process | 9.5E-248 |
