Gene Card
Best human hits
CDK12; CDK13; CDK9
Species
Unique Gene ID
Phmamm.g00013492
Gene Model ID
Phmamm.CG.MTP2014.S1063.g13492
Location
S1063:7004..10290
Transcript Models and Sequences
AHC0AAA43YJ13
Plate: Plate_43_J13
AHC0AAA45YI21
Plate: Plate_45_I21
AHC0AAA65YG17
Plate: Plate_65_G17
AHC0AAA119YK22
Plate: Plate_119_K22
AHC0AAA123YB09
Plate: Plate_123_B09
AHC0AAA165YI20
Plate: Plate_165_I20
AHC0AAA193YE10
Plate: Plate_193_E10
AHC0AAA200YH04
Plate: Plate_200_H04
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | SMART | Protein kinase domain |
Prot_kinase_dom | Pfam | Protein kinase domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Orthology | molecular function |
DNA binding | Orthology | molecular function |
chromatin binding | Orthology | molecular function |
RNA binding | Orthology | molecular function |
protein kinase activity | Orthology | molecular function |
protein serine/threonine kinase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
extracellular region | Blast | cellular component |
extracellular space | Blast | cellular component |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Blast | cellular component |
DNA repair | Orthology | biological process |
transcription, DNA-templated | Orthology | biological process |
regulation of transcription, DNA-templated | Orthology | biological process |
transcription from RNA polymerase II promoter | Orthology | biological process |
transcription initiation from RNA polymerase II promoter | Orthology | biological process |
mRNA processing | Orthology | biological process |
protein phosphorylation | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
transcription factor binding | Orthology | molecular function |
cell proliferation | Orthology | biological process |
membrane | Orthology | cellular component |
kinase activity | Orthology | molecular function |
phosphorylation | Orthology | biological process |
nuclear speck | Blast | cellular component |
transferase activity | Orthology | molecular function |
protein kinase binding | Orthology | molecular function |
transcription regulatory region DNA binding | Orthology | molecular function |
positive regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
cell cycle | Orthology | biological process |
molecular transducer activity | Orthology | molecular function |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
nucleoplasm part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
nuclear body | Orthology | cellular component |
DNA replication | Orthology | biological process |
organelle organization | Orthology | biological process |
cytoplasmic part | Orthology | cellular component |
regulation of transcription from RNA polymerase II promoter | Orthology | biological process |
negative regulation of gene expression | Orthology | biological process |
protein ubiquitination | Orthology | biological process |
nucleolus | Blast | cellular component |
intracellular part | Blast | cellular component |
nuclear part | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
endomembrane system | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 583 | 0.0 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding | Hs | molecular function | 583 | 0.0 |
transcription coactivator binding | Hs | molecular function | 583 | 0.0 |
fibrillar center | Hs | cellular component | 296 | 2.32e-90 |
cyclin K-CDK12 complex | Hs | cellular component | 296 | 2.32e-90 |
cyclin K-CDK13 complex | Hs | cellular component | 293 | 2.37e-89 |
DNA binding | Hs | molecular function | 583 | 0.0 |
chromatin binding | Hs | molecular function | 583 | 0.0 |
RNA binding | Hs | molecular function | 293 | 2.37e-89 |
protein kinase activity | Hs | molecular function | 583 | 0.0 |
protein serine/threonine kinase activity | Hs | molecular function | 583 | 0.0 |
cyclin-dependent protein serine/threonine kinase activity | Hs | molecular function | 583 | 0.0 |
protein binding | Hs | molecular function | 583 | 0.0 |
ATP binding | Hs | molecular function | 583 | 0.0 |
extracellular region | Hs | cellular component | 293 | 2.37e-89 |
extracellular space | Hs | cellular component | 293 | 2.37e-89 |
nucleus | Hs | cellular component | 583 | 0.0 |
nucleoplasm | Hs | cellular component | 583 | 0.0 |
chromosome | Hs | cellular component | 583 | 0.0 |
cytoplasm | Hs | cellular component | 583 | 0.0 |
Golgi apparatus | Hs | cellular component | 293 | 2.37e-89 |
cytosol | Hs | cellular component | 293 | 2.37e-89 |
transcription elongation factor complex | Hs | cellular component | 583 | 0.0 |
cyclin/CDK positive transcription elongation factor complex | Hs | cellular component | 583 | 0.0 |
transcription factor binding | Hs | molecular function | 583 | 0.0 |
RNA polymerase II carboxy-terminal domain kinase activity | Hs | molecular function | 583 | 0.0 |
membrane | Hs | cellular component | 583 | 0.0 |
kinase activity | Hs | molecular function | 583 | 0.0 |
PML body | Hs | cellular component | 583 | 0.0 |
nuclear speck | Hs | cellular component | 296 | 2.32e-90 |
transferase activity | Hs | molecular function | 583 | 0.0 |
snRNA binding | Hs | molecular function | 583 | 0.0 |
protein kinase binding | Hs | molecular function | 583 | 0.0 |
nuclear cyclin-dependent protein kinase holoenzyme complex | Hs | cellular component | 296 | 2.32e-90 |
cyclin binding | Hs | molecular function | 583 | 0.0 |
cytoplasmic ribonucleoprotein granule | Hs | cellular component | 583 | 0.0 |
transcription regulatory region DNA binding | Hs | molecular function | 583 | 0.0 |
7SK snRNA binding | Hs | molecular function | 583 | 0.0 |
ficolin-1-rich granule lumen | Hs | cellular component | 293 | 2.37e-89 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | SMART | molecular function | 4.1E-90 |
ATP binding | SMART | molecular function | 4.1E-90 |
protein phosphorylation | SMART | biological process | 4.1E-90 |