IPR Term	Analysis	Definition
Ig-like_dom_sf	SUPERFAMILY	Immunoglobulin-like domain superfamily
Kringle_CS	ProSitePatterns	Kringle, conserved site
Ser-Thr/Tyr_kinase_cat_dom	Pfam	Serine-threonine/tyrosine-protein kinase, catalytic domain
Frizzled_dom	ProSiteProfiles	Frizzled domain
Frizzled_dom_sf	Gene3D	Frizzled cysteine-rich domain superfamily
Tyr_kinase_cat_dom	SMART	Tyrosine-protein kinase, catalytic domain
Ig-like_fold	Gene3D	Immunoglobulin-like fold
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Prot_kinase_dom	SMART	Protein kinase domain
Kringle	SMART	Kringle
Kringle	CDD	Kringle
Ig-like_dom	ProSiteProfiles	Immunoglobulin-like domain
Protein_kinase_ATP_BS	ProSitePatterns	Protein kinase, ATP binding site
Kringle_sf	Gene3D	Kringle superfamily
Kringle	Pfam	Kringle
Tyr_kinase_AS	ProSitePatterns	Tyrosine-protein kinase, active site
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
Kringle-like	SUPERFAMILY	Kringle-like fold
Ser-Thr/Tyr_kinase_cat_dom	PRINTS	Serine-threonine/tyrosine-protein kinase, catalytic domain
Kringle	ProSiteProfiles	Kringle

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
protein kinase activity	Orthology	molecular function
receptor binding	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
extracellular region	Blast	cellular component
intracellular	Blast	cellular component
nucleus	Blast	cellular component
cytoplasm	Orthology	cellular component
cytosol	Blast	cellular component
microtubule	Orthology	cellular component
plasma membrane	Orthology	cellular component
integral component of plasma membrane	Orthology	cellular component
protein phosphorylation	Orthology	biological process
signal transduction	Orthology	biological process
multicellular organism development	Orthology	biological process
sensory perception of sound	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
cell surface	Orthology	cellular component
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
cell migration	Orthology	biological process
transferase activity	Orthology	molecular function
cell differentiation	Orthology	biological process
axon	Orthology	cellular component
cell projection	Orthology	cellular component
neuronal cell body	Orthology	cellular component
positive regulation of transcription, DNA-templated	Orthology	biological process
metal ion binding	Orthology	molecular function
regulation of canonical Wnt signaling pathway	Orthology	biological process
extracellular exosome	Blast	cellular component
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
system development	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
cytoskeletal part	Orthology	cellular component
anatomical structure formation involved in morphogenesis	Orthology	biological process
transmembrane signaling receptor activity	Orthology	molecular function
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
cellular response to stress	Orthology	biological process
intracellular signal transduction	Orthology	biological process
cell development	Orthology	biological process
neurogenesis	Orthology	biological process
central nervous system development	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cellular response to organic substance	Orthology	biological process
reproductive process	Orthology	biological process
whole membrane	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
cytoplasmic vesicle	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
macromolecular complex	Orthology	cellular component
positive regulation of catalytic activity	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
cell projection part	Orthology	cellular component
synapse part	Orthology	cellular component
chemical synaptic transmission	Orthology	biological process
signaling receptor activity	Orthology	molecular function
immune system process	Orthology	biological process
intracellular part	Blast	cellular component
plasma membrane part	Blast	cellular component
lysosome	Blast	cellular component
vacuolar part	Blast	cellular component
endomembrane system	Blast	cellular component
intracellular organelle lumen	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
skeletal system development	Hs	biological process
cartilage condensation	Hs	biological process
stress fiber	Hs	cellular component
somitogenesis	Hs	biological process
protein kinase activity	Hs	molecular function
protein tyrosine kinase activity	Hs	molecular function
transmembrane receptor protein tyrosine kinase activity	Hs	molecular function
frizzled binding	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
cytoplasm	Hs	cellular component
microtubule	Hs	cellular component
plasma membrane	Hs	cellular component
integral component of plasma membrane	Hs	cellular component
protein phosphorylation	Hs	biological process
signal transduction	Hs	biological process
transmembrane receptor protein tyrosine kinase signaling pathway	Hs	biological process
Wnt signaling pathway, calcium modulating pathway	Hs	biological process
smoothened signaling pathway	Hs	biological process
JNK cascade	Hs	biological process
multicellular organism development	Hs	biological process
sensory perception of sound	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
cell surface	Hs	cellular component
astrocyte development	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
Wnt signaling pathway	Hs	biological process
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
transferase activity	Hs	molecular function
Wnt-protein binding	Hs	molecular function
peptidyl-tyrosine phosphorylation	Hs	biological process
cell differentiation	Hs	biological process
bone mineralization	Hs	biological process
positive regulation of cell migration	Hs	biological process
axon	Hs	cellular component
dendrite	Hs	cellular component
BMP signaling pathway	Hs	biological process
embryonic genitalia morphogenesis	Hs	biological process
male genitalia development	Hs	biological process
clathrin-coated endocytic vesicle membrane	Hs	cellular component
inner ear morphogenesis	Hs	biological process
Wnt-activated receptor activity	Hs	molecular function
cell projection	Hs	cellular component
neuronal cell body	Hs	cellular component
positive regulation of I-kappaB kinase/NF-kappaB signaling	Hs	biological process
receptor complex	Hs	cellular component
positive regulation of JUN kinase activity	Hs	biological process
axon terminus	Hs	cellular component
cell fate commitment	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
metal ion binding	Hs	molecular function
inner ear development	Hs	biological process
positive regulation of NF-kappaB transcription factor activity	Hs	biological process
positive regulation of synaptic transmission, glutamatergic	Hs	biological process
Wnt signaling pathway, planar cell polarity pathway	Hs	biological process
SMAD protein signal transduction	Hs	biological process
regulation of canonical Wnt signaling pathway	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Hs	molecular function
macrophage migration	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	426	1.17e-134
stress fiber	Hs	cellular component	413	4.69e-130
protein kinase activity	Hs	molecular function	426	1.17e-134
protein tyrosine kinase activity	Hs	molecular function	426	1.17e-134
transmembrane receptor protein tyrosine kinase activity	Hs	molecular function	426	1.17e-134
non-membrane spanning protein tyrosine kinase activity	Hs	molecular function	161	3.20e-42
receptor binding	Hs	molecular function	161	3.20e-42
frizzled binding	Hs	molecular function	426	1.17e-134
protein binding	Hs	molecular function	426	1.17e-134
ATP binding	Hs	molecular function	426	1.17e-134
extracellular region	Hs	cellular component	161	3.20e-42
intracellular	Hs	cellular component	161	3.20e-42
nucleus	Hs	cellular component	161	3.20e-42
cytoplasm	Hs	cellular component	426	1.17e-134
cytosol	Hs	cellular component	161	3.20e-42
microtubule	Hs	cellular component	426	1.17e-134
plasma membrane	Hs	cellular component	426	1.17e-134
integral component of plasma membrane	Hs	cellular component	426	1.17e-134
cell surface	Hs	cellular component	426	1.17e-134
membrane	Hs	cellular component	426	1.17e-134
integral component of membrane	Hs	cellular component	426	1.17e-134
kinase activity	Hs	molecular function	426	1.17e-134
transferase activity	Hs	molecular function	426	1.17e-134
Wnt-protein binding	Hs	molecular function	426	1.17e-134
axon	Hs	cellular component	413	4.69e-130
dendrite	Hs	cellular component	426	1.17e-134
clathrin-coated endocytic vesicle membrane	Hs	cellular component	426	1.17e-134
extrinsic component of cytoplasmic side of plasma membrane	Hs	cellular component	161	3.20e-42
azurophil granule lumen	Hs	cellular component	161	3.20e-42
specific granule lumen	Hs	cellular component	161	3.20e-42
Wnt-activated receptor activity	Hs	molecular function	413	4.69e-130
cell projection	Hs	cellular component	413	4.69e-130
neuronal cell body	Hs	cellular component	426	1.17e-134
receptor complex	Hs	cellular component	413	4.69e-130
axon terminus	Hs	cellular component	413	4.69e-130
metal ion binding	Hs	molecular function	426	1.17e-134
extracellular exosome	Hs	cellular component	161	3.20e-42
coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Hs	molecular function	426	1.17e-134

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	1.6E-54
protein tyrosine kinase activity	SMART	molecular function	2.2E-66
protein binding	Gene3D	molecular function	2.3E-21
ATP binding	SMART	molecular function	2.7E-12
protein phosphorylation	SMART	biological process	2.2E-66