IPR Term	Analysis	Definition
Isy1_sf	SUPERFAMILY	Pre-mRNA-splicing factor Isy1 superfamily
Isy1	PANTHER	Pre-mRNA-splicing factor Isy1
Helix_hairpin_bin_sf	Gene3D	Helix hairpin bin domain superfamily
Isy1	Pfam	Pre-mRNA-splicing factor Isy1

GO Term	Annotation Origin	Type
mRNA splicing, via spliceosome	Orthology	biological process
RNA binding	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
mRNA processing	Orthology	biological process
RNA splicing	Orthology	biological process
catalytic activity	Orthology	molecular function
RNA splicing, via transesterification reactions	Orthology	biological process
macromolecular complex	Orthology	cellular component
nuclear part	Orthology	cellular component
DNA repair	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
generation of catalytic spliceosome for second transesterification step	Hs	biological process
first spliceosomal transesterification activity	Hs	molecular function
mRNA 3'-splice site recognition	Hs	biological process
mRNA splicing, via spliceosome	Hs	biological process
Prp19 complex	Hs	cellular component
RNA binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
spliceosomal complex	Hs	cellular component
transcription-coupled nucleotide-excision repair	Hs	biological process
mRNA processing	Hs	biological process
RNA splicing	Hs	biological process
catalytic step 1 spliceosome	Hs	cellular component
catalytic step 2 spliceosome	Hs	cellular component
post-mRNA release spliceosomal complex	Hs	cellular component
post-spliceosomal complex	Hs	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
first spliceosomal transesterification activity	Hs	molecular function	331	2.25e-114
Prp19 complex	Hs	cellular component	331	2.25e-114
RNA binding	Hs	molecular function	331	2.25e-114
protein binding	Hs	molecular function	331	2.25e-114
nucleus	Hs	cellular component	331	2.25e-114
nucleoplasm	Hs	cellular component	331	2.25e-114
spliceosomal complex	Hs	cellular component	331	2.25e-114
catalytic step 1 spliceosome	Hs	cellular component	331	2.25e-114
catalytic step 2 spliceosome	Hs	cellular component	331	2.25e-114
post-mRNA release spliceosomal complex	Hs	cellular component	331	2.25e-114
post-spliceosomal complex	Hs	cellular component	331	2.25e-114

GO Term	Analysis	Type	e-value
generation of catalytic spliceosome for second transesterification step	PANTHER	biological process	1.3E-105