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GENE CARD

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Gene Card

Best human hits

C4B; C5

Species

P.mammillata

Unique Gene ID

Phmamm.g00003789

Gene Model ID

Phmamm.CG.MTP2014.S127.g03789

Location

S127:160074..190480

Transcript Models and Sequences

  Phmamm.CG.MTP2014.S127.g03789.01.t

External Database Gene Card

External database links

No result

Collections

Genoscope Yasuo Villefranche

1 result

AHC0AAA129YA07

Plate: Plate_129_A07

WashU Genome Browser

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Genomicus Synteny Browser

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Regulatory Regions

Regulatory Regions

No result

n/a

Gene Phylogeny

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Gene Annotations

InterPro

15 results

IPR Term Analysis Definition
A2M_N_2 Pfam Alpha-2-macroglobulin, N-terminal 2
Macroglobln_a2 SMART Alpha-2-macroglobulin
TIMP-like_OB-fold SUPERFAMILY Tissue inhibitor of metalloproteinases-like, OB-fold
Terpenoid_cyclase/PrenylTrfase SUPERFAMILY Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
A-macroglobulin_rcpt-bd_sf Gene3D Alpha-macroglobulin, receptor-binding domain superfamily
A2M_N_2 SMART Alpha-2-macroglobulin, N-terminal 2
A-macroglobulin_rcpt-bd_sf SUPERFAMILY Alpha-macroglobulin, receptor-binding domain superfamily
A-macroglobulin_rcpt-bd SMART Alpha-macroglobulin, receptor-binding
Netrin_domain ProSiteProfiles Netrin domain
MacrogloblnA2_CS ProSitePatterns Alpha-2-macroglobulin, conserved site
Macroglobln_a2 Pfam Alpha-2-macroglobulin
A2M_N Pfam Alpha-2-macroglobulin, N-terminal
Ig-like_fold Gene3D Immunoglobulin-like fold
A-macroglobulin_rcpt-bd Pfam Alpha-macroglobulin, receptor-binding
A2M_comp Pfam Alpha-macroglobulin complement component

GOSlim

51 results

GO Term Annotation Origin Type
immune system process Orthology biological process
serine-type endopeptidase activity Orthology molecular function
receptor binding Orthology molecular function
protein binding Orthology molecular function
extracellular region Orthology cellular component
extracellular space Orthology cellular component
plasma membrane Orthology cellular component
proteolysis Orthology biological process
chemotaxis Orthology biological process
cell surface receptor signaling pathway Orthology biological process
G-protein coupled receptor signaling pathway Orthology biological process
cell junction Orthology cellular component
axon Orthology cellular component
cell projection Orthology cellular component
innate immune response Orthology biological process
synapse Orthology cellular component
extracellular exosome Orthology cellular component
endoplasmic reticulum lumen Orthology cellular component
immune response Orthology biological process
signal transduction Orthology biological process
macromolecular complex Orthology cellular component
neuronal cell body Orthology cellular component
positive regulation of catalytic activity Orthology biological process
intracellular signal transduction Orthology biological process
protein serine/threonine kinase activity Orthology molecular function
positive regulation of signal transduction Orthology biological process
endopeptidase activity Orthology molecular function
enzyme regulator activity Orthology molecular function
enzyme binding Orthology molecular function
integral component of plasma membrane Orthology cellular component
defense response Orthology biological process
protein metabolic process Orthology biological process
cell migration Orthology biological process
molecular function regulator Orthology molecular function
signaling receptor activity Orthology molecular function
regulation of signal transduction Orthology biological process
cellular process Orthology biological process
binding Orthology molecular function
angiogenesis Orthology biological process
protein phosphorylation Orthology biological process
organic substance metabolic process Orthology biological process
cellular metabolic process Orthology biological process
membrane organization Orthology biological process
organelle organization Orthology biological process
intracellular organelle part Orthology cellular component
cytoplasmic vesicle Orthology cellular component
endomembrane system Orthology cellular component
intracellular organelle lumen Orthology cellular component
lysosome Orthology cellular component
vacuolar part Orthology cellular component
cellular protein modification process Orthology biological process

GO (Orthology)

54 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type
activation of MAPK activity Hs biological process
complement binding Hs molecular function
immune system process Hs biological process
serine-type endopeptidase activity Hs molecular function
endopeptidase inhibitor activity Hs molecular function
receptor binding Hs molecular function
protein binding Hs molecular function
extracellular region Hs cellular component
membrane attack complex Hs cellular component
extracellular space Hs cellular component
plasma membrane Hs cellular component
proteolysis Hs biological process
chemotaxis Hs biological process
inflammatory response Hs biological process
complement activation Hs biological process
complement activation, alternative pathway Hs biological process
complement activation, classical pathway Hs biological process
cell surface receptor signaling pathway Hs biological process
G-protein coupled receptor signaling pathway Hs biological process
chemokine activity Hs molecular function
positive regulation of vascular endothelial growth factor production Hs biological process
negative regulation of endopeptidase activity Hs biological process
cytolysis Hs biological process
cell junction Hs cellular component
carbohydrate binding Hs molecular function
axon Hs cellular component
dendrite Hs cellular component
cell projection Hs cellular component
other organism cell Hs cellular component
innate immune response Hs biological process
synapse Hs cellular component
positive regulation of angiogenesis Hs biological process
cell chemotaxis Hs biological process
extracellular exosome Hs cellular component
blood microparticle Hs cellular component
complement component C1q binding Hs molecular function
positive regulation of protein phosphorylation Hs biological process
endoplasmic reticulum lumen Hs cellular component
lipid metabolic process Hs biological process
fatty acid metabolic process Hs biological process
phagocytosis, engulfment Hs biological process
immune response Hs biological process
signal transduction Hs biological process
regulation of triglyceride biosynthetic process Hs biological process
positive regulation of lipid storage Hs biological process
C5L2 anaphylatoxin chemotactic receptor binding Hs molecular function
macromolecular complex Hs cellular component
secretory granule lumen Hs cellular component
azurophil granule lumen Hs cellular component
neuronal cell body Hs cellular component
post-translational protein modification Hs biological process
positive regulation of G-protein coupled receptor protein signaling pathway Hs biological process
positive regulation of phagocytosis Hs biological process
regulation of immune response Hs biological process

GO (Blast)

19 results

GO Term SpeciesCe = Caenorhabditis elegans
Dr = Danio rerio
Dm = Drosophila melanogaster
Gg = Gallus gallus
Hs = Homo sapiens
Mm = Mus musculus
Sc = Saccharomyces cerevisiae
Type Score E-value
complement binding Hs molecular function 280 4.21e-76
serine-type endopeptidase activity Hs molecular function 280 4.21e-76
endopeptidase inhibitor activity Hs molecular function 301 1.23e-82
receptor binding Hs molecular function 301 1.23e-82
protein binding Hs molecular function 301 1.23e-82
extracellular region Hs cellular component 301 1.23e-82
membrane attack complex Hs cellular component 301 1.23e-82
extracellular space Hs cellular component 301 1.23e-82
plasma membrane Hs cellular component 280 4.21e-76
chemokine activity Hs molecular function 301 1.23e-82
cell junction Hs cellular component 280 4.21e-76
carbohydrate binding Hs molecular function 280 4.21e-76
axon Hs cellular component 280 4.21e-76
dendrite Hs cellular component 280 4.21e-76
cell projection Hs cellular component 280 4.21e-76
other organism cell Hs cellular component 280 4.21e-76
synapse Hs cellular component 280 4.21e-76
extracellular exosome Hs cellular component 301 1.23e-82
blood microparticle Hs cellular component 280 4.21e-76

GO (InterProScan)

4 results

GO Term Analysis Type e-value
endopeptidase inhibitor activity Pfam molecular function 4.0E-15
protein binding ProSiteProfiles molecular function 9.556
extracellular region Gene3D cellular component 4.7E-124
extracellular space Pfam cellular component 7.7E-81