IPR Term	Analysis	Definition
TRAF-like	SUPERFAMILY	TRAF-like
TRAF-like	Gene3D	TRAF-like
TRAF4	PANTHER	TNF receptor-associated factor 4
Znf_TRAF	ProSiteProfiles	Zinc finger, TRAF-type
Znf_RING/FYVE/PHD	Gene3D	Zinc finger, RING/FYVE/PHD-type
TRAF4_MATH	CDD	TNF receptor-associated factor 4, MATH domain
MATH/TRAF_dom	ProSiteProfiles	MATH/TRAF domain
TNF_rcpt--assoc_TRAF	PIRSF	TNF receptor-associated factor TRAF
MATH/TRAF_dom	SMART	MATH/TRAF domain
Znf_TRAF	Pfam	Zinc finger, TRAF-type

GO Term	Annotation Origin	Type
DNA binding	Orthology	molecular function
ubiquitin-protein transferase activity	Blast	molecular function
signal transducer activity	Blast	molecular function
receptor binding	Orthology	molecular function
protein binding	Orthology	molecular function
intracellular	Orthology	cellular component
nucleus	Orthology	cellular component
nucleoplasm	Blast	cellular component
cytoplasm	Orthology	cellular component
cytosol	Blast	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Orthology	cellular component
apoptotic process	Orthology	biological process
signal transduction	Orthology	biological process
multicellular organism development	Orthology	biological process
zinc ion binding	Orthology	molecular function
membrane	Orthology	cellular component
transferase activity	Blast	molecular function
enzyme binding	Orthology	molecular function
protein kinase binding	Orthology	molecular function
cell junction	Orthology	cellular component
ubiquitin protein ligase binding	Orthology	molecular function
macromolecular complex	Blast	cellular component
identical protein binding	Orthology	molecular function
regulation of apoptotic process	Orthology	biological process
membrane raft	Blast	cellular component
metal ion binding	Orthology	molecular function
protein N-terminus binding	Blast	molecular function
perinuclear region of cytoplasm	Orthology	cellular component
positive regulation of catalytic activity	Orthology	biological process
enzyme regulator activity	Orthology	molecular function
protein kinase activity	Orthology	molecular function
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
intracellular signal transduction	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
cellular response to stress	Orthology	biological process
protein phosphorylation	Orthology	biological process
intracellular part	Blast	cellular component
intracellular non-membrane-bounded organelle	Blast	cellular component
cell periphery	Blast	cellular component
cytoplasmic part	Blast	cellular component
binding	Blast	molecular function
plasma membrane part	Blast	cellular component
intracellular organelle part	Blast	cellular component
whole membrane	Blast	cellular component
endosome	Blast	cellular component
bounding membrane of organelle	Blast	cellular component
vesicle	Blast	cellular component
organelle membrane	Blast	cellular component
integral component of plasma membrane	Blast	cellular component
endoplasmic reticulum membrane	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
DNA binding	Hs	molecular function
tumor necrosis factor receptor binding	Hs	molecular function
protein binding	Hs	molecular function
intracellular	Hs	cellular component
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
cytoskeleton	Hs	cellular component
plasma membrane	Hs	cellular component
bicellular tight junction	Hs	cellular component
apoptotic process	Hs	biological process
signal transduction	Hs	biological process
activation of NF-kappaB-inducing kinase activity	Hs	biological process
multicellular organism development	Hs	biological process
zinc ion binding	Hs	molecular function
membrane	Hs	cellular component
protein kinase binding	Hs	molecular function
cell junction	Hs	cellular component
ubiquitin protein ligase binding	Hs	molecular function
thioesterase binding	Hs	molecular function
identical protein binding	Hs	molecular function
regulation of apoptotic process	Hs	biological process
positive regulation of protein kinase activity	Hs	biological process
positive regulation of JNK cascade	Hs	biological process
metal ion binding	Hs	molecular function
perinuclear region of cytoplasm	Hs	cellular component
WW domain binding	Hs	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
ubiquitin ligase complex	Hs	cellular component	165	3.16e-46
DNA binding	Hs	molecular function	442	7.81e-154
ubiquitin-protein transferase activity	Hs	molecular function	165	3.16e-46
signal transducer activity	Hs	molecular function	165	3.16e-46
receptor binding	Hs	molecular function	165	3.16e-46
tumor necrosis factor receptor binding	Hs	molecular function	442	7.81e-154
CD40 receptor binding	Hs	molecular function	165	3.16e-46
protein binding	Hs	molecular function	442	7.81e-154
intracellular	Hs	cellular component	442	7.81e-154
nucleus	Hs	cellular component	442	7.81e-154
nucleoplasm	Hs	cellular component	165	3.16e-46
cytoplasm	Hs	cellular component	442	7.81e-154
lipid droplet	Hs	cellular component	138	2.92e-36
cytosol	Hs	cellular component	165	3.16e-46
cytoskeleton	Hs	cellular component	442	7.81e-154
plasma membrane	Hs	cellular component	442	7.81e-154
bicellular tight junction	Hs	cellular component	442	7.81e-154
cell cortex	Hs	cellular component	165	3.16e-46
zinc ion binding	Hs	molecular function	442	7.81e-154
lipid binding	Hs	molecular function	165	3.16e-46
cytoplasmic side of plasma membrane	Hs	cellular component	165	3.16e-46
endosome membrane	Hs	cellular component	138	2.92e-36
vesicle membrane	Hs	cellular component	165	3.16e-46
membrane	Hs	cellular component	442	7.81e-154
transferase activity	Hs	molecular function	165	3.16e-46
enzyme binding	Hs	molecular function	165	3.16e-46
protein kinase binding	Hs	molecular function	442	7.81e-154
protein phosphatase binding	Hs	molecular function	165	3.16e-46
cell junction	Hs	cellular component	442	7.81e-154
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function	165	3.16e-46
ubiquitin conjugating enzyme binding	Hs	molecular function	138	2.92e-36
ubiquitin protein ligase binding	Hs	molecular function	442	7.81e-154
thioesterase binding	Hs	molecular function	442	7.81e-154
macromolecular complex	Hs	cellular component	138	2.92e-36
CD40 receptor complex	Hs	cellular component	165	3.16e-46
identical protein binding	Hs	molecular function	442	7.81e-154
histone deacetylase binding	Hs	molecular function	138	2.92e-36
protein kinase B binding	Hs	molecular function	138	2.92e-36
membrane raft	Hs	cellular component	165	3.16e-46
sphingolipid binding	Hs	molecular function	165	3.16e-46
metal ion binding	Hs	molecular function	442	7.81e-154
protein N-terminus binding	Hs	molecular function	138	2.92e-36
perinuclear region of cytoplasm	Hs	cellular component	442	7.81e-154
WW domain binding	Hs	molecular function	442	7.81e-154
ubiquitin protein ligase activity	Hs	molecular function	138	2.92e-36
TRAF2-GSTP1 complex	Hs	cellular component	165	3.16e-46
AIP1-IRE1 complex	Hs	cellular component	165	3.16e-46
IRE1-TRAF2-ASK1 complex	Hs	cellular component	165	3.16e-46

GO Term	Analysis	Type	e-value
protein binding	Gene3D	molecular function	1.1E-61
signal transduction	PIRSF	biological process	2.8E-71
activation of NF-kappaB-inducing kinase activity	CDD	biological process	6.63071E-106
zinc ion binding	PIRSF	molecular function	2.8E-71
regulation of apoptotic process	PIRSF	biological process	2.8E-71
positive regulation of JNK cascade	CDD	biological process	6.63071E-106