Gene Card
Best human hits
CASP3; CASP6; CASP7
Species
Unique Gene ID
Phmamm.g00000620
Gene Model ID
Phmamm.CG.MTP2014.S14.g00620
Location
S14:294867..297396
Transcript Models and Sequences
AHC0AAA26YD12
Plate: Plate_26_D12
AHC0AAA108YP19
Plate: Plate_108_P19
AHC0AAA221YN13
Plate: Plate_221_N13
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Caspase_6 | PANTHER | Caspase-6 |
Pept_C14_p10 | ProSiteProfiles | Peptidase C14, caspase non-catalytic subunit p10 |
Pept_C14A | SMART | Peptidase C14A, caspase catalytic domain |
Caspase_cys_AS | ProSitePatterns | Peptidase family C14A, cysteine active site |
Pept_C14_p20 | ProSiteProfiles | Peptidase C14, p20 domain |
Pept_C14A | PRINTS | Peptidase C14A, caspase catalytic domain |
Pept_C14A | CDD | Peptidase C14A, caspase catalytic domain |
Caspase_his_AS | ProSitePatterns | Peptidase family C14A, His active site |
Caspase-like_dom_sf | SUPERFAMILY | Caspase-like domain superfamily |
GO Term | Annotation Origin | Type |
---|---|---|
endopeptidase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Blast | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Blast | cellular component |
proteolysis | Orthology | biological process |
apoptotic process | Orthology | biological process |
peptidase activity | Orthology | molecular function |
hydrolase activity | Orthology | molecular function |
identical protein binding | Orthology | molecular function |
regulation of apoptotic process | Orthology | biological process |
positive regulation of apoptotic process | Blast | biological process |
intracellular membrane-bounded organelle | Blast | cellular component |
membrane raft | Blast | cellular component |
peptidase activity, acting on L-amino acid peptides | Orthology | molecular function |
anatomical structure development | Orthology | biological process |
cell differentiation | Orthology | biological process |
cell projection assembly | Orthology | biological process |
enzyme binding | Blast | molecular function |
cell cycle | Blast | biological process |
enzyme regulator activity | Blast | molecular function |
protein kinase binding | Blast | molecular function |
molecular transducer activity | Blast | molecular function |
protein serine/threonine kinase activity | Blast | molecular function |
receptor binding | Blast | molecular function |
enzyme activator activity | Blast | molecular function |
positive regulation of hydrolase activity | Blast | biological process |
plasma membrane part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
endopeptidase activity | Hs | molecular function |
cysteine-type endopeptidase activity | Hs | molecular function |
protein binding | Hs | molecular function |
nucleoplasm | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
proteolysis | Hs | biological process |
apoptotic process | Hs | biological process |
peptidase activity | Hs | molecular function |
cysteine-type peptidase activity | Hs | molecular function |
hydrolase activity | Hs | molecular function |
epithelial cell differentiation | Hs | biological process |
identical protein binding | Hs | molecular function |
regulation of apoptotic process | Hs | biological process |
execution phase of apoptosis | Hs | biological process |
cysteine-type endopeptidase activity involved in execution phase of apoptosis | Hs | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
protease binding | Hs | molecular function | 170 | 9.28e-52 |
endopeptidase activity | Hs | molecular function | 188 | 1.83e-58 |
aspartic-type endopeptidase activity | Hs | molecular function | 170 | 9.28e-52 |
cysteine-type endopeptidase activity | Hs | molecular function | 188 | 1.83e-58 |
cyclin-dependent protein serine/threonine kinase inhibitor activity | Hs | molecular function | 170 | 9.28e-52 |
death receptor binding | Hs | molecular function | 170 | 9.28e-52 |
protein binding | Hs | molecular function | 188 | 1.83e-58 |
nucleus | Hs | cellular component | 170 | 9.28e-52 |
nucleoplasm | Hs | cellular component | 188 | 1.83e-58 |
cytoplasm | Hs | cellular component | 188 | 1.83e-58 |
cytosol | Hs | cellular component | 188 | 1.83e-58 |
plasma membrane | Hs | cellular component | 170 | 9.28e-52 |
peptidase activity | Hs | molecular function | 188 | 1.83e-58 |
cysteine-type peptidase activity | Hs | molecular function | 188 | 1.83e-58 |
cysteine-type endopeptidase activator activity involved in apoptotic process | Hs | molecular function | 170 | 9.28e-52 |
phospholipase A2 activator activity | Hs | molecular function | 170 | 9.28e-52 |
hydrolase activity | Hs | molecular function | 188 | 1.83e-58 |
death-inducing signaling complex | Hs | cellular component | 170 | 9.28e-52 |
identical protein binding | Hs | molecular function | 188 | 1.83e-58 |
intracellular membrane-bounded organelle | Hs | cellular component | 163 | 6.25e-48 |
membrane raft | Hs | cellular component | 170 | 9.28e-52 |
cysteine-type endopeptidase activity involved in apoptotic process | Hs | molecular function | 170 | 9.28e-52 |
cysteine-type endopeptidase activity involved in execution phase of apoptosis | Hs | molecular function | 188 | 1.83e-58 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
cysteine-type endopeptidase activity | PANTHER | molecular function | 1.5E-80 |
proteolysis | ProSiteProfiles | biological process | 15.386 |
apoptotic process | PANTHER | biological process | 1.5E-80 |
cysteine-type peptidase activity | CDD | molecular function | 1.21825E-72 |
cysteine-type endopeptidase activity involved in execution phase of apoptosis | PANTHER | molecular function | 1.5E-80 |