Gene Card
Best human hits
CYP3A4; CYP3A5; CYP3A7
Species
Unique Gene ID
Phmamm.g00004152
Gene Model ID
Phmamm.CG.MTP2014.S145.g04152
Location
S145:186026..200930
Transcript Models and Sequences
n/a
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
13 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Cyt_P450 | Pfam | Cytochrome P450 |
| Cyt_P450_CS | ProSitePatterns | Cytochrome P450, conserved site |
| Cyt_P450_sf | Gene3D | Cytochrome P450 superfamily |
| AAA+_ATPase | SMART | AAA+ ATPase domain |
| Leu-rich_rpt | Pfam | Leucine-rich repeat |
| NACHT_NTPase | Pfam | NACHT nucleoside triphosphatase |
| Cyt_P450 | PRINTS | Cytochrome P450 |
| LRR_dom_sf | Gene3D | Leucine-rich repeat domain superfamily |
| NACHT_NTPase | ProSiteProfiles | NACHT nucleoside triphosphatase |
| Cyt_P450_E_grp-I | PRINTS | Cytochrome P450, E-class, group I |
| Cyt_P450_sf | SUPERFAMILY | Cytochrome P450 superfamily |
| P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
| Leu-rich_rpt_Cys-con_subtyp | SMART | Leucine-rich repeat, cysteine-containing subtype |
GOSlim
17 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| iron ion binding | Blast | molecular function |
| cytoplasm | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| endoplasmic reticulum membrane | Blast | cellular component |
| membrane | Blast | cellular component |
| integral component of membrane | Blast | cellular component |
| enzyme binding | Blast | molecular function |
| heme binding | Blast | molecular function |
| organelle membrane | Blast | cellular component |
| intracellular membrane-bounded organelle | Blast | cellular component |
| metal ion binding | Blast | molecular function |
| oxidation-reduction process | Blast | biological process |
| protein binding | InterProScan | molecular function |
| catalytic activity | Blast | molecular function |
| organic cyclic compound binding | Blast | molecular function |
| small molecule binding | Blast | molecular function |
| cellular biosynthetic process | Blast | biological process |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
24 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| monooxygenase activity | Hs | molecular function | 179 | 8.59e-48 |
| steroid binding | Hs | molecular function | 179 | 8.59e-48 |
| iron ion binding | Hs | molecular function | 179 | 8.59e-48 |
| cytoplasm | Hs | cellular component | 179 | 8.59e-48 |
| endoplasmic reticulum | Hs | cellular component | 179 | 8.59e-48 |
| endoplasmic reticulum membrane | Hs | cellular component | 179 | 8.59e-48 |
| steroid hydroxylase activity | Hs | molecular function | 179 | 8.59e-48 |
| membrane | Hs | cellular component | 179 | 8.59e-48 |
| integral component of membrane | Hs | cellular component | 179 | 8.59e-48 |
| oxidoreductase activity | Hs | molecular function | 179 | 8.59e-48 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | Hs | molecular function | 179 | 8.59e-48 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | Hs | molecular function | 179 | 8.59e-48 |
| oxygen binding | Hs | molecular function | 179 | 8.59e-48 |
| enzyme binding | Hs | molecular function | 179 | 8.59e-48 |
| heme binding | Hs | molecular function | 179 | 8.59e-48 |
| vitamin D3 25-hydroxylase activity | Hs | molecular function | 179 | 8.59e-48 |
| organelle membrane | Hs | cellular component | 179 | 8.59e-48 |
| caffeine oxidase activity | Hs | molecular function | 179 | 8.59e-48 |
| intracellular membrane-bounded organelle | Hs | cellular component | 179 | 8.59e-48 |
| metal ion binding | Hs | molecular function | 179 | 8.59e-48 |
| testosterone 6-beta-hydroxylase activity | Hs | molecular function | 179 | 8.59e-48 |
| aromatase activity | Hs | molecular function | 176 | 6.50e-47 |
| vitamin D 24-hydroxylase activity | Hs | molecular function | 179 | 8.59e-48 |
| estrogen 16-alpha-hydroxylase activity | Hs | molecular function | 179 | 8.59e-48 |
GO (InterProScan)
5 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| iron ion binding | SUPERFAMILY | molecular function | 9.3E-79 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | SUPERFAMILY | molecular function | 9.3E-79 |
| heme binding | SUPERFAMILY | molecular function | 9.3E-79 |
| oxidation-reduction process | SUPERFAMILY | biological process | 9.3E-79 |
| protein binding | Pfam | molecular function | 0.0018 |
