Gene Card
Best human hits
MAP3K7; RIPK1; RIPK2
Species
Unique Gene ID
Phmamm.g00014872
Gene Model ID
Phmamm.CG.MTP2014.S1464.g14872
Location
S1464:35494..37086
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | Pfam | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Prot_kinase_dom | SMART | Protein kinase domain |
Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Blast | molecular function |
magnesium ion binding | Blast | molecular function |
protein kinase activity | Blast | molecular function |
protein serine/threonine kinase activity | Blast | molecular function |
signal transducer activity | Blast | molecular function |
receptor binding | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
nucleus | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Blast | cellular component |
cytosol | Blast | cellular component |
cytoskeleton | Blast | cellular component |
plasma membrane | Blast | cellular component |
protein phosphorylation | InterProScan | biological process |
membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
transferase activity | Blast | molecular function |
ubiquitin protein ligase binding | Blast | molecular function |
vesicle | Blast | cellular component |
macromolecular complex | Blast | cellular component |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
macromolecular complex binding | Blast | molecular function |
membrane raft | Blast | cellular component |
metal ion binding | Blast | molecular function |
positive regulation of catalytic activity | Blast | biological process |
intracellular signal transduction | Blast | biological process |
positive regulation of signal transduction | Blast | biological process |
nucleoplasm part | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
whole membrane | Blast | cellular component |
endosome | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
plasma membrane part | Blast | cellular component |
enzyme binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 116 | 5.90e-28 |
magnesium ion binding | Hs | molecular function | 105 | 2.36e-24 |
protein kinase activity | Hs | molecular function | 116 | 5.90e-28 |
protein serine/threonine kinase activity | Hs | molecular function | 116 | 5.90e-28 |
MAP kinase kinase kinase activity | Hs | molecular function | 105 | 2.36e-24 |
non-membrane spanning protein tyrosine kinase activity | Hs | molecular function | 99.4 | 1.78e-22 |
signal transducer activity | Hs | molecular function | 116 | 5.90e-28 |
receptor binding | Hs | molecular function | 99.4 | 1.78e-22 |
death receptor binding | Hs | molecular function | 116 | 5.90e-28 |
protein binding | Hs | molecular function | 116 | 5.90e-28 |
ATP binding | Hs | molecular function | 116 | 5.90e-28 |
nucleus | Hs | cellular component | 105 | 2.36e-24 |
Ada2/Gcn5/Ada3 transcription activator complex | Hs | cellular component | 105 | 2.36e-24 |
cytoplasm | Hs | cellular component | 116 | 5.90e-28 |
mitochondrion | Hs | cellular component | 116 | 5.90e-28 |
cytosol | Hs | cellular component | 116 | 5.90e-28 |
cytoskeleton | Hs | cellular component | 99.4 | 1.78e-22 |
plasma membrane | Hs | cellular component | 116 | 5.90e-28 |
IkappaB kinase complex | Hs | cellular component | 105 | 2.36e-24 |
endosome membrane | Hs | cellular component | 116 | 5.90e-28 |
membrane | Hs | cellular component | 116 | 5.90e-28 |
kinase activity | Hs | molecular function | 116 | 5.90e-28 |
transferase activity | Hs | molecular function | 116 | 5.90e-28 |
LIM domain binding | Hs | molecular function | 99.4 | 1.78e-22 |
death-inducing signaling complex | Hs | cellular component | 116 | 5.90e-28 |
ubiquitin protein ligase binding | Hs | molecular function | 116 | 5.90e-28 |
vesicle | Hs | cellular component | 99.4 | 1.78e-22 |
macromolecular complex | Hs | cellular component | 99.4 | 1.78e-22 |
identical protein binding | Hs | molecular function | 116 | 5.90e-28 |
protein homodimerization activity | Hs | molecular function | 99.4 | 1.78e-22 |
receptor complex | Hs | cellular component | 116 | 5.90e-28 |
macromolecular complex binding | Hs | molecular function | 116 | 5.90e-28 |
membrane raft | Hs | cellular component | 116 | 5.90e-28 |
metal ion binding | Hs | molecular function | 105 | 2.36e-24 |
CARD domain binding | Hs | molecular function | 99.4 | 1.78e-22 |
death domain binding | Hs | molecular function | 116 | 5.90e-28 |
caspase binding | Hs | molecular function | 99.4 | 1.78e-22 |
scaffold protein binding | Hs | molecular function | 105 | 2.36e-24 |
ripoptosome | Hs | cellular component | 116 | 5.90e-28 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 3.6E-42 |
ATP binding | Pfam | molecular function | 3.6E-42 |
protein phosphorylation | Pfam | biological process | 3.6E-42 |