IPR Term	Analysis	Definition
WD40_repeat	ProSiteProfiles	WD40 repeat
Polycomb_EED	PANTHER	Polycomb protein EED
WD40_repeat_dom_sf	SUPERFAMILY	WD40-repeat-containing domain superfamily
WD40_repeat_CS	ProSitePatterns	WD40 repeat, conserved site
WD40/YVTN_repeat-like_dom_sf	Gene3D	WD40/YVTN repeat-like-containing domain superfamily
WD40_repeat	SMART	WD40 repeat
WD40_repeat	Pfam	WD40 repeat
WD40_repeat_dom	ProSiteProfiles	WD40-repeat-containing domain

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Orthology	molecular function
chromatin binding	Orthology	molecular function
ubiquitin-protein transferase activity	Blast	molecular function
protein binding	Orthology	molecular function
intracellular	Blast	cellular component
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Blast	cellular component
cytosol	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
identical protein binding	Orthology	molecular function
cell projection	Blast	cellular component
negative regulation of transcription, DNA-templated	Orthology	biological process
intracellular non-membrane-bounded organelle	Orthology	cellular component
nuclear lumen	Orthology	cellular component
organelle organization	Orthology	biological process
nucleobase-containing compound metabolic process	Orthology	biological process
regulation of gene expression	Orthology	biological process
cellular protein modification process	Orthology	biological process
animal organ development	Orthology	biological process
central nervous system development	Orthology	biological process
nucleoplasm part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
transferase activity	Orthology	molecular function
negative regulation of gene expression	Orthology	biological process
organelle	Blast	cellular component
plasma membrane region	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
sex chromatin	Hs	cellular component
chromatin binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
chromosome	Hs	cellular component
cytosol	Hs	cellular component
chromatin organization	Hs	biological process
regulation of gene expression by genetic imprinting	Hs	biological process
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
histone methylation	Hs	biological process
spinal cord development	Hs	biological process
ESC/E(Z) complex	Hs	cellular component
histone methyltransferase activity	Hs	molecular function
identical protein binding	Hs	molecular function
pronucleus	Hs	cellular component
negative regulation of gene expression, epigenetic	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
histone methyltransferase activity (H3-K27 specific)	Hs	molecular function
histone H3-K27 methylation	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	298	3.33e-99
sex chromatin	Hs	cellular component	298	3.33e-99
chromatin binding	Hs	molecular function	298	3.33e-99
ubiquitin-protein transferase activity	Hs	molecular function	63.9	1.31e-11
protein binding	Hs	molecular function	298	3.33e-99
intracellular	Hs	cellular component	63.9	1.31e-11
nucleus	Hs	cellular component	298	3.33e-99
nucleoplasm	Hs	cellular component	298	3.33e-99
chromosome	Hs	cellular component	298	3.33e-99
cytoplasm	Hs	cellular component	69.3	2.07e-13
cytosol	Hs	cellular component	298	3.33e-99
cilium	Hs	cellular component	69.3	2.07e-13
ESC/E(Z) complex	Hs	cellular component	298	3.33e-99
histone methyltransferase activity	Hs	molecular function	298	3.33e-99
identical protein binding	Hs	molecular function	298	3.33e-99
cell projection	Hs	cellular component	69.3	2.07e-13
pronucleus	Hs	cellular component	298	3.33e-99
histone methyltransferase activity (H3-K27 specific)	Hs	molecular function	298	3.33e-99

GO Term	Analysis	Type	e-value
protein binding	Gene3D	molecular function	1.6E-67
histone methylation	PANTHER	biological process	1.5E-89
ESC/E(Z) complex	PANTHER	cellular component	1.5E-89