IPR Term	Analysis	Definition
WH-like_DNA-bd_sf	Gene3D	Winged helix-like DNA-binding domain superfamily
WH_DNA-bd_sf	SUPERFAMILY	Winged helix DNA-binding domain superfamily
ESCRT-2_cplx_Snf8	PANTHER	ESCRT-2 complex, Snf8

GO Term	Annotation Origin	Type
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
endosome	Orthology	cellular component
cytosol	Orthology	cellular component
plasma membrane	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
protein C-terminus binding	Orthology	molecular function
transcription factor binding	Orthology	molecular function
positive regulation of gene expression	Orthology	biological process
protein transport	Orthology	biological process
membrane	Orthology	cellular component
protein homodimerization activity	Orthology	molecular function
protein N-terminus binding	Orthology	molecular function
perinuclear region of cytoplasm	Orthology	cellular component
regulation of molecular function	Orthology	biological process
extracellular exosome	Orthology	cellular component
membrane part	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
macromolecular complex	Orthology	cellular component
intracellular part	Orthology	cellular component
intracellular transport	Orthology	biological process
cellular component organization	Orthology	biological process
molecular function regulator	Orthology	molecular function
protein metabolic process	Orthology	biological process
intracellular protein transport	Orthology	biological process
vacuole	Orthology	cellular component
proteolysis	Orthology	biological process
establishment of protein localization to organelle	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
ESCRT II complex	Hs	cellular component
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
transcription factor complex	Hs	cellular component
cytoplasm	Hs	cellular component
endosome	Hs	cellular component
cytosol	Hs	cellular component
plasma membrane	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
protein C-terminus binding	Hs	molecular function
transcription factor binding	Hs	molecular function
endosome membrane	Hs	cellular component
positive regulation of gene expression	Hs	biological process
regulation of multivesicular body size involved in endosome transport	Hs	biological process
protein transport	Hs	biological process
membrane	Hs	cellular component
endosomal transport	Hs	biological process
macroautophagy	Hs	biological process
channel regulator activity	Hs	molecular function
late endosome membrane	Hs	cellular component
endocytic recycling	Hs	biological process
multivesicular body assembly	Hs	biological process
regulation of protein catabolic process	Hs	biological process
protein homodimerization activity	Hs	molecular function
protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	Hs	biological process
early endosome to late endosome transport	Hs	biological process
positive regulation of protein catabolic process	Hs	biological process
protein N-terminus binding	Hs	molecular function
perinuclear region of cytoplasm	Hs	cellular component
recycling endosome	Hs	cellular component
regulation of protein complex stability	Hs	biological process
regulation of molecular function	Hs	biological process
extracellular exosome	Hs	cellular component
multivesicular body sorting pathway	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
ESCRT II complex	Hs	cellular component	281	3.19e-96
protein binding	Hs	molecular function	281	3.19e-96
nucleus	Hs	cellular component	281	3.19e-96
nucleoplasm	Hs	cellular component	281	3.19e-96
transcription factor complex	Hs	cellular component	281	3.19e-96
cytoplasm	Hs	cellular component	281	3.19e-96
endosome	Hs	cellular component	281	3.19e-96
cytosol	Hs	cellular component	281	3.19e-96
plasma membrane	Hs	cellular component	281	3.19e-96
protein C-terminus binding	Hs	molecular function	281	3.19e-96
transcription factor binding	Hs	molecular function	281	3.19e-96
endosome membrane	Hs	cellular component	281	3.19e-96
membrane	Hs	cellular component	281	3.19e-96
channel regulator activity	Hs	molecular function	281	3.19e-96
late endosome membrane	Hs	cellular component	281	3.19e-96
protein homodimerization activity	Hs	molecular function	281	3.19e-96
protein N-terminus binding	Hs	molecular function	281	3.19e-96
perinuclear region of cytoplasm	Hs	cellular component	281	3.19e-96
recycling endosome	Hs	cellular component	281	3.19e-96
extracellular exosome	Hs	cellular component	281	3.19e-96

GO Term	Analysis	Type	e-value
ESCRT II complex	PANTHER	cellular component	1.1E-81
multivesicular body sorting pathway	PANTHER	biological process	1.1E-81