Gene Card
Best human hits
LRP5; LRP6
Species
Unique Gene ID
Phmamm.g00005510
Gene Model ID
Phmamm.CG.MTP2014.S214.g05510
Location
S214:95970..111487
Transcript Models and Sequences
Phmamm.CG.MTP2014.S214.g05510.01.t
Phmamm.CG.MTP2014.S214.g05510.02.t
AHC0AAA44YF21
Plate: Plate_44_F21
AHC0AAA131YK04
Plate: Plate_131_K04
AHC0AAA193YF15
Plate: Plate_193_F15
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
LDLR_classB_rpt | ProSiteProfiles | LDLR class B repeat |
EGF-like_dom | SMART | EGF-like domain |
LDLR_classB_rpt | SMART | LDLR class B repeat |
6-blade_b-propeller_TolB-like | Gene3D | Six-bladed beta-propeller, TolB-like |
HYR_dom | ProSiteProfiles | HYR domain |
HYR_dom | Pfam | HYR domain |
SGL | Pfam | SMP-30/Gluconolactonase/LRE-like region |
Kringle_sf | Gene3D | Kringle superfamily |
Kringle_CS | ProSitePatterns | Kringle, conserved site |
Kringle | CDD | Kringle |
Kringle | Pfam | Kringle |
Kringle-like | SUPERFAMILY | Kringle-like fold |
Kringle | ProSiteProfiles | Kringle |
Kringle | SMART | Kringle |
GO Term | Annotation Origin | Type |
---|---|---|
receptor binding | Blast | molecular function |
protein binding | Blast | molecular function |
extracellular region | Blast | cellular component |
mitochondrion | Blast | cellular component |
early endosome | Blast | cellular component |
endoplasmic reticulum | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
plasma membrane | Blast | cellular component |
cell surface | Blast | cellular component |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
identical protein binding | Blast | molecular function |
protein homodimerization activity | Blast | molecular function |
neuronal cell body | Blast | cellular component |
membrane raft | Blast | cellular component |
synapse | Blast | cellular component |
membrane organization | Blast | biological process |
organelle organization | Blast | biological process |
macromolecular complex binding | Blast | molecular function |
plasma membrane region | Blast | cellular component |
kinase activity | Blast | molecular function |
enzyme regulator activity | Blast | molecular function |
transmembrane transport | Blast | biological process |
whole membrane | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
cell surface receptor signaling pathway | Blast | biological process |
cell-cell signaling | Blast | biological process |
transmembrane signaling receptor activity | Blast | molecular function |
macromolecular complex | Blast | cellular component |
signaling receptor activity | Blast | molecular function |
plasma membrane part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
low-density lipoprotein receptor activity | Hs | molecular function | 107 | 2.09e-23 |
receptor binding | Hs | molecular function | 107 | 2.09e-23 |
frizzled binding | Hs | molecular function | 107 | 2.09e-23 |
protein binding | Hs | molecular function | 107 | 2.09e-23 |
extracellular region | Hs | cellular component | 107 | 2.09e-23 |
mitochondrion | Hs | cellular component | 101 | 1.08e-21 |
early endosome | Hs | cellular component | 107 | 2.09e-23 |
endoplasmic reticulum | Hs | cellular component | 107 | 2.09e-23 |
Golgi apparatus | Hs | cellular component | 107 | 2.09e-23 |
plasma membrane | Hs | cellular component | 107 | 2.09e-23 |
caveola | Hs | cellular component | 107 | 2.09e-23 |
cell surface | Hs | cellular component | 107 | 2.09e-23 |
membrane | Hs | cellular component | 107 | 2.09e-23 |
integral component of membrane | Hs | cellular component | 107 | 2.09e-23 |
Wnt-protein binding | Hs | molecular function | 107 | 2.09e-23 |
kinase inhibitor activity | Hs | molecular function | 107 | 2.09e-23 |
toxin transporter activity | Hs | molecular function | 107 | 2.09e-23 |
cytoplasmic vesicle | Hs | cellular component | 107 | 2.09e-23 |
early endosome membrane | Hs | cellular component | 107 | 2.09e-23 |
apolipoprotein binding | Hs | molecular function | 107 | 2.09e-23 |
identical protein binding | Hs | molecular function | 107 | 2.09e-23 |
protein homodimerization activity | Hs | molecular function | 107 | 2.09e-23 |
Wnt-activated receptor activity | Hs | molecular function | 107 | 2.09e-23 |
neuronal cell body | Hs | cellular component | 107 | 2.09e-23 |
receptor complex | Hs | cellular component | 107 | 2.09e-23 |
membrane raft | Hs | cellular component | 107 | 2.09e-23 |
synapse | Hs | cellular component | 107 | 2.09e-23 |
coreceptor activity involved in Wnt signaling pathway | Hs | molecular function | 107 | 2.09e-23 |
coreceptor activity involved in canonical Wnt signaling pathway | Hs | molecular function | 107 | 2.09e-23 |
Wnt-Frizzled-LRP5/6 complex | Hs | cellular component | 107 | 2.09e-23 |
Wnt signalosome | Hs | cellular component | 107 | 2.09e-23 |
GO Term | Analysis | Type | e-value |
---|