Gene Card
Best human hits
ITK; LYN; RIPK1
Species
Unique Gene ID
Phmamm.g00016354
Gene Model ID
Phmamm.CG.MTP2014.S2196.g16354
Location
S2196:16836..19481
Transcript Models and Sequences
AHC0AAA19YL16
Plate: Plate_19_L16
AHC0AAA23YE08
Plate: Plate_23_E08
AHC0AAA264YA02
Plate: Plate_264_A02
n/a
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IPR Term | Analysis | Definition |
---|---|---|
Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
Ser-Thr/Tyr_kinase_cat_dom | Pfam | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Protein_kinase_ATP_BS | ProSitePatterns | Protein kinase, ATP binding site |
Prot_kinase_dom | Pfam | Protein kinase domain |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Blast | molecular function |
protein kinase activity | Blast | molecular function |
protein serine/threonine kinase activity | Blast | molecular function |
signal transducer activity | Blast | molecular function |
receptor binding | Blast | molecular function |
integrin binding | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
intracellular | Blast | cellular component |
nucleus | Blast | cellular component |
cytoplasm | Blast | cellular component |
mitochondrion | Blast | cellular component |
Golgi apparatus | Blast | cellular component |
cytosol | Blast | cellular component |
plasma membrane | Blast | cellular component |
protein phosphorylation | InterProScan | biological process |
membrane | Blast | cellular component |
kinase activity | Blast | molecular function |
transferase activity | Blast | molecular function |
enzyme binding | Blast | molecular function |
ubiquitin protein ligase binding | Blast | molecular function |
mitochondrial membrane | Blast | cellular component |
identical protein binding | Blast | molecular function |
intracellular membrane-bounded organelle | Blast | cellular component |
macromolecular complex binding | Blast | molecular function |
membrane raft | Blast | cellular component |
metal ion binding | Blast | molecular function |
perinuclear region of cytoplasm | Blast | cellular component |
extracellular exosome | Blast | cellular component |
mitochondrial envelope | Blast | cellular component |
intracellular organelle lumen | Blast | cellular component |
cell junction | Blast | cellular component |
adherens junction | Blast | cellular component |
intracellular organelle part | Blast | cellular component |
whole membrane | Blast | cellular component |
endosome | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
organelle | Blast | cellular component |
postsynapse | Blast | cellular component |
neuron part | Blast | cellular component |
membrane part | Blast | cellular component |
mitochondrial inner membrane | Blast | cellular component |
intracellular part | Blast | cellular component |
plasma membrane part | Blast | cellular component |
macromolecular complex | Blast | cellular component |
integral component of plasma membrane | Blast | cellular component |
lysosome | Blast | cellular component |
tubulin binding | Blast | molecular function |
carbohydrate derivative binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 65.1 | 9.11e-12 |
protein kinase activity | Hs | molecular function | 65.1 | 9.11e-12 |
protein serine/threonine kinase activity | Hs | molecular function | 57.4 | 3.05e-09 |
protein tyrosine kinase activity | Hs | molecular function | 65.1 | 9.11e-12 |
non-membrane spanning protein tyrosine kinase activity | Hs | molecular function | 65.1 | 9.11e-12 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity | Hs | molecular function | 51.6 | 1.79e-07 |
signal transducer activity | Hs | molecular function | 57.4 | 3.05e-09 |
receptor binding | Hs | molecular function | 51.6 | 1.79e-07 |
death receptor binding | Hs | molecular function | 57.4 | 3.05e-09 |
platelet-derived growth factor receptor binding | Hs | molecular function | 51.6 | 1.79e-07 |
integrin binding | Hs | molecular function | 51.6 | 1.79e-07 |
protein binding | Hs | molecular function | 65.1 | 9.11e-12 |
ATP binding | Hs | molecular function | 65.1 | 9.11e-12 |
intracellular | Hs | cellular component | 65.1 | 9.11e-12 |
nucleus | Hs | cellular component | 65.1 | 9.11e-12 |
cytoplasm | Hs | cellular component | 65.1 | 9.11e-12 |
mitochondrion | Hs | cellular component | 57.4 | 3.05e-09 |
mitochondrial intermembrane space | Hs | cellular component | 51.6 | 1.79e-07 |
Golgi apparatus | Hs | cellular component | 51.6 | 1.79e-07 |
cytosol | Hs | cellular component | 65.1 | 9.11e-12 |
plasma membrane | Hs | cellular component | 57.4 | 3.05e-09 |
cell-cell junction | Hs | cellular component | 65.1 | 9.11e-12 |
cell-cell adherens junction | Hs | cellular component | 51.6 | 1.79e-07 |
endosome membrane | Hs | cellular component | 57.4 | 3.05e-09 |
postsynaptic density | Hs | cellular component | 51.6 | 1.79e-07 |
membrane | Hs | cellular component | 57.4 | 3.05e-09 |
kinase activity | Hs | molecular function | 65.1 | 9.11e-12 |
transferase activity | Hs | molecular function | 65.1 | 9.11e-12 |
SH3 domain binding | Hs | molecular function | 51.6 | 1.79e-07 |
enzyme binding | Hs | molecular function | 51.6 | 1.79e-07 |
mitochondrial crista | Hs | cellular component | 51.6 | 1.79e-07 |
extrinsic component of cytoplasmic side of plasma membrane | Hs | cellular component | 65.1 | 9.11e-12 |
death-inducing signaling complex | Hs | cellular component | 57.4 | 3.05e-09 |
ubiquitin protein ligase binding | Hs | molecular function | 57.4 | 3.05e-09 |
mitochondrial membrane | Hs | cellular component | 51.6 | 1.79e-07 |
integrin alpha2-beta1 complex | Hs | cellular component | 51.6 | 1.79e-07 |
mast cell granule | Hs | cellular component | 51.6 | 1.79e-07 |
identical protein binding | Hs | molecular function | 57.4 | 3.05e-09 |
gamma-tubulin binding | Hs | molecular function | 51.6 | 1.79e-07 |
glycosphingolipid binding | Hs | molecular function | 51.6 | 1.79e-07 |
intracellular membrane-bounded organelle | Hs | cellular component | 51.6 | 1.79e-07 |
receptor complex | Hs | cellular component | 57.4 | 3.05e-09 |
ion channel binding | Hs | molecular function | 51.6 | 1.79e-07 |
macromolecular complex binding | Hs | molecular function | 57.4 | 3.05e-09 |
membrane raft | Hs | cellular component | 57.4 | 3.05e-09 |
metal ion binding | Hs | molecular function | 65.1 | 9.11e-12 |
ephrin receptor binding | Hs | molecular function | 51.6 | 1.79e-07 |
perinuclear region of cytoplasm | Hs | cellular component | 51.6 | 1.79e-07 |
phosphoprotein binding | Hs | molecular function | 51.6 | 1.79e-07 |
extracellular exosome | Hs | cellular component | 51.6 | 1.79e-07 |
death domain binding | Hs | molecular function | 57.4 | 3.05e-09 |
ripoptosome | Hs | cellular component | 57.4 | 3.05e-09 |
phosphorylation-dependent protein binding | Hs | molecular function | 51.6 | 1.79e-07 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein kinase activity | Pfam | molecular function | 9.3E-12 |
ATP binding | Pfam | molecular function | 9.3E-12 |
protein phosphorylation | Pfam | biological process | 9.3E-12 |