IPR Term	Analysis	Definition
L-lactate_DH_AS	ProSitePatterns	L-lactate dehydrogenase, active site
Lactate_DH/Glyco_Ohase_4_C	SUPERFAMILY	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Lactate/malate_DH_N	Pfam	Lactate/malate dehydrogenase, N-terminal
L-lactate/malate_DH	PRINTS	L-lactate/malate dehydrogenase
NAD(P)-bd_dom_sf	SUPERFAMILY	NAD(P)-binding domain superfamily
Lactate_DH/Glyco_Ohase_4_C	Gene3D	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
L-lactate/malate_DH	PIRSF	L-lactate/malate dehydrogenase
Lactate/malate_DH_C	Pfam	Lactate/malate dehydrogenase, C-terminal

GO Term	Annotation Origin	Type
response to hypoxia	Orthology	biological process
catalytic activity	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
cytosol	Orthology	cellular component
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
kinase binding	Orthology	molecular function
identical protein binding	Orthology	molecular function
positive regulation of apoptotic process	Orthology	biological process
myelin sheath	Orthology	cellular component
membrane raft	Orthology	cellular component
oxidation-reduction process	Orthology	biological process
extracellular exosome	Orthology	cellular component
mitochondrial matrix	Orthology	cellular component
organelle	Orthology	cellular component
cell projection	Orthology	cellular component
plasma membrane region	Orthology	cellular component
macromolecular complex	Orthology	cellular component
organic substance metabolic process	Orthology	biological process
cellular metabolic process	Orthology	biological process
nucleobase-containing compound metabolic process	Orthology	biological process
kinase activity	Orthology	molecular function
phosphate-containing compound metabolic process	Orthology	biological process
response to organic substance	Orthology	biological process
metabolic process	Orthology	biological process
reproductive process	Orthology	biological process
cell motility	Orthology	biological process
response to oxidative stress	Orthology	biological process
response to stimulus	Orthology	biological process
cell adhesion molecule binding	Orthology	molecular function
nucleotide binding	Orthology	molecular function
coenzyme binding	Orthology	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
response to hypoxia	Hs	biological process
catalytic activity	Hs	molecular function
lactate dehydrogenase activity	Hs	molecular function
L-lactate dehydrogenase activity	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
cytosol	Hs	cellular component
cilium	Hs	cellular component
carbohydrate metabolic process	Hs	biological process
pyruvate metabolic process	Hs	biological process
glycolytic process	Hs	biological process
ATP biosynthetic process	Hs	biological process
response to nutrient	Hs	biological process
response to glucose	Hs	biological process
response to organic cyclic compound	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
oxidoreductase activity	Hs	molecular function
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Hs	molecular function
NAD metabolic process	Hs	biological process
carboxylic acid metabolic process	Hs	biological process
kinase binding	Hs	molecular function
flagellated sperm motility	Hs	biological process
motile cilium	Hs	cellular component
response to drug	Hs	biological process
response to hydrogen peroxide	Hs	biological process
identical protein binding	Hs	molecular function
positive regulation of apoptotic process	Hs	biological process
myelin sheath	Hs	cellular component
response to estrogen	Hs	biological process
membrane raft	Hs	cellular component
cadherin binding	Hs	molecular function
NAD binding	Hs	molecular function
response to cAMP	Hs	biological process
oxidation-reduction process	Hs	biological process
extracellular exosome	Hs	cellular component
mitochondrial matrix	Hs	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
catalytic activity	Hs	molecular function	307	5.44e-105
lactate dehydrogenase activity	Hs	molecular function	307	5.44e-105
L-lactate dehydrogenase activity	Hs	molecular function	307	5.44e-105
protein binding	Hs	molecular function	307	5.44e-105
nucleus	Hs	cellular component	302	1.31e-102
cytoplasm	Hs	cellular component	307	5.44e-105
mitochondrion	Hs	cellular component	307	5.44e-105
cytosol	Hs	cellular component	307	5.44e-105
cilium	Hs	cellular component	297	4.25e-101
membrane	Hs	cellular component	307	5.44e-105
integral component of membrane	Hs	cellular component	302	1.31e-102
oxidoreductase activity	Hs	molecular function	307	5.44e-105
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Hs	molecular function	307	5.44e-105
kinase binding	Hs	molecular function	307	5.44e-105
motile cilium	Hs	cellular component	297	4.25e-101
identical protein binding	Hs	molecular function	307	5.44e-105
myelin sheath	Hs	cellular component	307	5.44e-105
membrane raft	Hs	cellular component	307	5.44e-105
cadherin binding	Hs	molecular function	302	1.31e-102
NAD binding	Hs	molecular function	307	5.44e-105
extracellular exosome	Hs	cellular component	307	5.44e-105

GO Term	Analysis	Type	e-value
catalytic activity	Gene3D	molecular function	6.6E-27
L-lactate dehydrogenase activity	ProSitePatterns	molecular function
carbohydrate metabolic process	Gene3D	biological process	6.6E-27
oxidoreductase activity	Pfam	molecular function	7.3E-44
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	PIRSF	molecular function	2.9E-70
carboxylic acid metabolic process	PIRSF	biological process	2.9E-70
oxidation-reduction process	PIRSF	biological process	2.9E-70