IPR Term	Analysis	Definition
Homeobox_CS	ProSitePatterns	Homeobox, conserved site
Homeobox_dom	Pfam	Homeobox domain
Homeobox_dom	ProSiteProfiles	Homeobox domain
Homeobox_metazoa	PRINTS	Homeobox domain, metazoa
Homeobox_dom	CDD	Homeobox domain
Homeobox_dom	SMART	Homeobox domain
Homeobox-like_sf	SUPERFAMILY	Homeobox-like domain superfamily
HTH_motif	PRINTS	Helix-turn-helix motif

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cell morphogenesis	Orthology	biological process
RNA polymerase II regulatory region sequence-specific DNA binding	Orthology	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
transcription factor activity, transcription factor binding	Orthology	molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Orthology	molecular function
DNA binding	Orthology	molecular function
chromatin binding	Blast	molecular function
transcription factor activity, sequence-specific DNA binding	Blast	molecular function
transcription cofactor activity	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription from RNA polymerase II promoter	Orthology	biological process
multicellular organism development	Orthology	biological process
heart development	Orthology	biological process
transcription factor binding	Orthology	molecular function
negative regulation of cell proliferation	Orthology	biological process
nuclear speck	Orthology	cellular component
wound healing	Orthology	biological process
regulation of apoptotic process	Orthology	biological process
negative regulation of apoptotic process	Orthology	biological process
sequence-specific DNA binding	Orthology	molecular function
transcription regulatory region DNA binding	Orthology	molecular function
negative regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cell differentiation	Orthology	biological process
animal organ development	Orthology	biological process
cell development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
brain development	Orthology	biological process
signal transduction	Orthology	biological process
regulation of gene expression	Orthology	biological process
cellular component organization	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
cellular response to organic substance	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
protein localization to organelle	Orthology	biological process
cell migration	Orthology	biological process
regulation of molecular function	Orthology	biological process
anatomical structure development	Orthology	biological process
head development	Orthology	biological process
response to lipid	Orthology	biological process
intracellular signal transduction	Orthology	biological process
positive regulation of apoptotic process	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
cell morphogenesis	Hs	biological process
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function
transcription factor activity, transcription factor binding	Hs	molecular function
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function
ossification	Hs	biological process
osteoblast differentiation	Hs	biological process
epithelial to mesenchymal transition	Hs	biological process
p53 binding	Hs	molecular function
chondrocyte development	Hs	biological process
osteoblast development	Hs	biological process
heart morphogenesis	Hs	biological process
outflow tract morphogenesis	Hs	biological process
DNA binding	Hs	molecular function
transcription cofactor activity	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytosol	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
transcription from RNA polymerase II promoter	Hs	biological process
multicellular organism development	Hs	biological process
heart development	Hs	biological process
muscle organ development	Hs	biological process
transcription factor binding	Hs	molecular function
negative regulation of cell proliferation	Hs	biological process
anterior/posterior pattern specification	Hs	biological process
nuclear speck	Hs	cellular component
pituitary gland development	Hs	biological process
signal transduction involved in regulation of gene expression	Hs	biological process
negative regulation of cell growth	Hs	biological process
embryonic limb morphogenesis	Hs	biological process
BMP signaling pathway	Hs	biological process
positive regulation of BMP signaling pathway	Hs	biological process
forebrain development	Hs	biological process
midbrain development	Hs	biological process
protein localization to nucleus	Hs	biological process
embryonic hindlimb morphogenesis	Hs	biological process
wound healing, spreading of epidermal cells	Hs	biological process
enhancer binding	Hs	molecular function
wound healing	Hs	biological process
odontogenesis	Hs	biological process
regulation of apoptotic process	Hs	biological process
negative regulation of apoptotic process	Hs	biological process
negative regulation of DNA binding	Hs	biological process
sequence-specific DNA binding	Hs	molecular function
transcription regulatory region DNA binding	Hs	molecular function
positive regulation of osteoblast differentiation	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
stem cell differentiation	Hs	biological process
protein stabilization	Hs	biological process
cartilage development	Hs	biological process
palate development	Hs	biological process
face morphogenesis	Hs	biological process
bone morphogenesis	Hs	biological process
cranial suture morphogenesis	Hs	biological process
cartilage morphogenesis	Hs	biological process
BMP signaling pathway involved in heart development	Hs	biological process
cellular response to estradiol stimulus	Hs	biological process
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Hs	biological process
negative regulation of transcription regulatory region DNA binding	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA polymerase II regulatory region sequence-specific DNA binding	Hs	molecular function	139	3.04e-40
RNA polymerase II transcription factor activity, sequence-specific DNA binding	Hs	molecular function	139	3.04e-40
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	139	3.04e-40
transcription factor activity, transcription factor binding	Hs	molecular function	138	3.51e-40
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	Hs	molecular function	82.0	1.70e-18
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function	139	3.04e-40
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	Hs	molecular function	139	3.04e-40
p53 binding	Hs	molecular function	139	3.04e-40
DNA binding	Hs	molecular function	139	3.04e-40
chromatin binding	Hs	molecular function	82.0	1.70e-18
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	82.0	1.70e-18
transcription cofactor activity	Hs	molecular function	138	3.51e-40
protein binding	Hs	molecular function	138	3.51e-40
nucleus	Hs	cellular component	139	3.04e-40
nucleoplasm	Hs	cellular component	139	3.04e-40
cytosol	Hs	cellular component	138	3.51e-40
transcription factor binding	Hs	molecular function	138	3.51e-40
nuclear speck	Hs	cellular component	138	3.51e-40
enhancer binding	Hs	molecular function	139	3.04e-40
sequence-specific DNA binding	Hs	molecular function	139	3.04e-40
transcription regulatory region DNA binding	Hs	molecular function	138	3.51e-40

GO Term	Analysis	Type	e-value
DNA binding	SMART	molecular function	1.8E-24
regulation of transcription, DNA-templated	ProSitePatterns	biological process
sequence-specific DNA binding	ProSitePatterns	molecular function