Gene Card
Best human hits
NLRP12; NLRP3; NLRP7
Species
Unique Gene ID
Phmamm.g00016732
Gene Model ID
Phmamm.CG.MTP2014.S2487.g16732
Location
S2487:10618..17515
Transcript Models and Sequences
AHC0AAA25YE23
Plate: Plate_25_E23
AHC0AAA91YC13
Plate: Plate_91_C13
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Leu-rich_rpt | Pfam | Leucine-rich repeat |
LRR_dom_sf | Gene3D | Leucine-rich repeat domain superfamily |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
NACHT_NTPase | ProSiteProfiles | NACHT nucleoside triphosphatase |
NACHT_NTPase | Pfam | NACHT nucleoside triphosphatase |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Blast | molecular function |
protein binding | Blast | molecular function |
ATP binding | Blast | molecular function |
extracellular region | Blast | cellular component |
nucleus | Blast | cellular component |
cytoplasm | Blast | cellular component |
endoplasmic reticulum | Blast | cellular component |
cytosol | Blast | cellular component |
transcription factor binding | Blast | molecular function |
identical protein binding | Blast | molecular function |
sequence-specific DNA binding | Blast | molecular function |
endopeptidase activity | Blast | molecular function |
enzyme activator activity | Blast | molecular function |
positive regulation of hydrolase activity | Blast | biological process |
enzyme binding | Blast | molecular function |
positive regulation of apoptotic process | Blast | biological process |
enzyme regulator activity | Blast | molecular function |
carbohydrate derivative binding | Blast | molecular function |
macromolecular complex | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 79.0 | 9.41e-15 |
protein binding | Hs | molecular function | 79.0 | 9.41e-15 |
ATP binding | Hs | molecular function | 79.0 | 9.41e-15 |
extracellular region | Hs | cellular component | 78.6 | 1.06e-14 |
nucleus | Hs | cellular component | 78.6 | 1.06e-14 |
cytoplasm | Hs | cellular component | 79.0 | 9.41e-15 |
endoplasmic reticulum | Hs | cellular component | 78.6 | 1.06e-14 |
cytosol | Hs | cellular component | 78.6 | 1.06e-14 |
transcription factor binding | Hs | molecular function | 78.6 | 1.06e-14 |
cysteine-type endopeptidase activator activity involved in apoptotic process | Hs | molecular function | 79.0 | 9.41e-15 |
aspartic-type endopeptidase inhibitor activity | Hs | molecular function | 73.9 | 2.86e-13 |
interleukin-1 binding | Hs | molecular function | 73.9 | 2.86e-13 |
identical protein binding | Hs | molecular function | 78.6 | 1.06e-14 |
peptidoglycan binding | Hs | molecular function | 78.6 | 1.06e-14 |
sequence-specific DNA binding | Hs | molecular function | 78.6 | 1.06e-14 |
inflammasome complex | Hs | cellular component | 78.6 | 1.06e-14 |
NLRP3 inflammasome complex | Hs | cellular component | 78.6 | 1.06e-14 |
caspase binding | Hs | molecular function | 73.9 | 2.86e-13 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
protein binding | Pfam | molecular function | 6.5E-4 |