IPR Term	Analysis	Definition
Helicase_C	CDD	Helicase, C-terminal
Helicase_C	SMART	Helicase, C-terminal
P-loop_NTPase	SUPERFAMILY	P-loop containing nucleoside triphosphate hydrolase
Helicase_ATP-bd	SMART	Helicase superfamily 1/2, ATP-binding domain
RNA-helicase_DEAD-box_CS	ProSitePatterns	ATP-dependent RNA helicase DEAD-box, conserved site
Helicase_C	ProSiteProfiles	Helicase, C-terminal
Helicase_ATP-bd	ProSiteProfiles	Helicase superfamily 1/2, ATP-binding domain
DEAD/DEAH_box_helicase_dom	Pfam	DEAD/DEAH box helicase domain
Helicase_C	Pfam	Helicase, C-terminal
RNA_helicase_DEAD_Q_motif	ProSiteProfiles	RNA helicase, DEAD-box type, Q motif

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
nucleotide binding	Orthology	molecular function
mRNA splicing, via spliceosome	Orthology	biological process
nuclear-transcribed mRNA catabolic process	Orthology	biological process
immune system process	Orthology	biological process
nucleic acid binding	Orthology	molecular function
transcription coactivator activity	Orthology	molecular function
RNA binding	Orthology	molecular function
protein binding	Orthology	molecular function
calmodulin binding	Orthology	molecular function
ATP binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
nucleolus	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
RNA processing	Orthology	biological process
mRNA processing	Orthology	biological process
RNA splicing	Orthology	biological process
membrane	Orthology	cellular component
nuclear speck	Orthology	cellular component
hydrolase activity	Orthology	molecular function
enzyme binding	Orthology	molecular function
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
extracellular exosome	Orthology	cellular component
regulation of gene expression	Orthology	biological process
animal organ development	Orthology	biological process
cell differentiation	Orthology	biological process
nucleoside-triphosphatase activity	Orthology	molecular function
nuclear part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
mRNA metabolic process	Orthology	biological process
RNA metabolic process	Orthology	biological process
cellular process	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
cellular response to organic substance	Orthology	biological process
signal transduction	Orthology	biological process
response to lipid	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
macromolecular complex binding	Orthology	molecular function
anatomical structure development	Orthology	biological process
receptor binding	Orthology	molecular function
transcription factor binding	Orthology	molecular function
defense response	Orthology	biological process
regulation of signal transduction	Orthology	biological process
intracellular	Orthology	cellular component
intracellular signal transduction	Orthology	biological process
apoptotic process	Orthology	biological process
chromatin binding	Orthology	molecular function
nuclear body	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
nucleotide binding	Hs	molecular function
alternative mRNA splicing, via spliceosome	Hs	biological process
regulation of alternative mRNA splicing, via spliceosome	Hs	biological process
mRNA splicing, via spliceosome	Hs	biological process
nuclear-transcribed mRNA catabolic process	Hs	biological process
epithelial to mesenchymal transition	Hs	biological process
immune system process	Hs	biological process
nucleic acid binding	Hs	molecular function
transcription coactivator activity	Hs	molecular function
RNA binding	Hs	molecular function
RNA helicase activity	Hs	molecular function
mRNA 3'-UTR binding	Hs	molecular function
ATP-dependent RNA helicase activity	Hs	molecular function
helicase activity	Hs	molecular function
protein binding	Hs	molecular function
calmodulin binding	Hs	molecular function
ATP binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
spliceosomal complex	Hs	cellular component
nucleolus	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
regulation of transcription from RNA polymerase II promoter	Hs	biological process
rRNA processing	Hs	biological process
RNA processing	Hs	biological process
mRNA processing	Hs	biological process
RNA-dependent ATPase activity	Hs	molecular function
RNA splicing	Hs	biological process
mRNA transcription	Hs	biological process
RNA secondary structure unwinding	Hs	biological process
miRNA metabolic process	Hs	biological process
membrane	Hs	cellular component
cell growth	Hs	biological process
nuclear speck	Hs	cellular component
hydrolase activity	Hs	molecular function
enzyme binding	Hs	molecular function
BMP signaling pathway	Hs	biological process
intracellular estrogen receptor signaling pathway	Hs	biological process
androgen receptor signaling pathway	Hs	biological process
intracellular ribonucleoprotein complex	Hs	cellular component
gene silencing by RNA	Hs	biological process
MH2 domain binding	Hs	molecular function
pre-mRNA binding	Hs	molecular function
ribonucleoprotein complex binding	Hs	molecular function
myoblast differentiation	Hs	biological process
regulation of osteoblast differentiation	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
SMAD binding	Hs	molecular function
calcium-dependent protein binding	Hs	molecular function
rhythmic process	Hs	biological process
androgen receptor binding	Hs	molecular function
defense response to virus	Hs	biological process
regulation of androgen receptor signaling pathway	Hs	biological process
extracellular exosome	Hs	cellular component
R-SMAD binding	Hs	molecular function
primary miRNA binding	Hs	molecular function
catalytic step 2 spliceosome	Hs	cellular component
SMAD protein complex	Hs	cellular component
intrinsic apoptotic signaling pathway by p53 class mediator	Hs	biological process
promoter-specific chromatin binding	Hs	molecular function
regulation of skeletal muscle cell differentiation	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	659	0.0
nucleic acid binding	Hs	molecular function	659	0.0
transcription coactivator activity	Hs	molecular function	655	0.0
RNA binding	Hs	molecular function	659	0.0
RNA helicase activity	Hs	molecular function	659	0.0
mRNA 3'-UTR binding	Hs	molecular function	659	0.0
ATP-dependent RNA helicase activity	Hs	molecular function	659	0.0
helicase activity	Hs	molecular function	659	0.0
protein binding	Hs	molecular function	659	0.0
calmodulin binding	Hs	molecular function	659	0.0
ATP binding	Hs	molecular function	659	0.0
nucleus	Hs	cellular component	659	0.0
nucleoplasm	Hs	cellular component	659	0.0
spliceosomal complex	Hs	cellular component	659	0.0
nucleolus	Hs	cellular component	659	0.0
cytoplasm	Hs	cellular component	659	0.0
cytosol	Hs	cellular component	655	0.0
RNA-dependent ATPase activity	Hs	molecular function	655	0.0
Cajal body	Hs	cellular component	362	9.52e-115
membrane	Hs	cellular component	659	0.0
nuclear speck	Hs	cellular component	655	0.0
hydrolase activity	Hs	molecular function	659	0.0
enzyme binding	Hs	molecular function	659	0.0
intracellular ribonucleoprotein complex	Hs	cellular component	659	0.0
MH2 domain binding	Hs	molecular function	659	0.0
pre-mRNA binding	Hs	molecular function	659	0.0
ribonucleoprotein complex binding	Hs	molecular function	659	0.0
SMAD binding	Hs	molecular function	659	0.0
calcium-dependent protein binding	Hs	molecular function	659	0.0
androgen receptor binding	Hs	molecular function	659	0.0
extracellular exosome	Hs	cellular component	659	0.0
R-SMAD binding	Hs	molecular function	659	0.0
primary miRNA binding	Hs	molecular function	659	0.0
catalytic step 2 spliceosome	Hs	cellular component	659	0.0
SMAD protein complex	Hs	cellular component	659	0.0
promoter-specific chromatin binding	Hs	molecular function	659	0.0

GO Term	Analysis	Type	e-value
nucleic acid binding	Pfam	molecular function	4.0E-50
ATP binding	Pfam	molecular function	4.0E-50