Gene Card
Best human hits
NLRP10; NLRP12; NLRP3
Species
Unique Gene ID
Phmamm.g00016898
Gene Model ID
Phmamm.CG.MTP2014.S2631.g16898
Location
S2631:1637..7678
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
5 results
| IPR Term | Analysis | Definition |
|---|---|---|
| P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
| NACHT_NTPase | Pfam | NACHT nucleoside triphosphatase |
| NACHT_NTPase | ProSiteProfiles | NACHT nucleoside triphosphatase |
| LRR_dom_sf | Gene3D | Leucine-rich repeat domain superfamily |
| Leu-rich_rpt | Pfam | Leucine-rich repeat |
GOSlim
23 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| nucleotide binding | Blast | molecular function |
| GTPase activity | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| cytosol | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| transcription factor binding | Blast | molecular function |
| membrane | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| sequence-specific DNA binding | Blast | molecular function |
| endopeptidase activity | Blast | molecular function |
| enzyme activator activity | Blast | molecular function |
| positive regulation of hydrolase activity | Blast | biological process |
| enzyme binding | Blast | molecular function |
| positive regulation of apoptotic process | Blast | biological process |
| nucleoside-triphosphatase activity | Blast | molecular function |
| plasma membrane part | Blast | cellular component |
| carbohydrate derivative binding | Blast | molecular function |
| macromolecular complex | Blast | cellular component |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
20 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 105 | 8.45e-23 |
| GTPase activity | Hs | molecular function | 86.7 | 2.70e-17 |
| protein binding | Hs | molecular function | 105 | 8.45e-23 |
| ATP binding | Hs | molecular function | 105 | 8.45e-23 |
| extracellular region | Hs | cellular component | 88.6 | 1.11e-17 |
| nucleus | Hs | cellular component | 88.6 | 1.11e-17 |
| cytoplasm | Hs | cellular component | 105 | 8.45e-23 |
| endoplasmic reticulum | Hs | cellular component | 88.6 | 1.11e-17 |
| cytosol | Hs | cellular component | 88.6 | 1.11e-17 |
| plasma membrane | Hs | cellular component | 86.7 | 2.70e-17 |
| transcription factor binding | Hs | molecular function | 88.6 | 1.11e-17 |
| cysteine-type endopeptidase activator activity involved in apoptotic process | Hs | molecular function | 105 | 8.45e-23 |
| membrane | Hs | cellular component | 86.7 | 2.70e-17 |
| ATPase activity | Hs | molecular function | 86.7 | 2.70e-17 |
| extrinsic component of plasma membrane | Hs | cellular component | 86.7 | 2.70e-17 |
| identical protein binding | Hs | molecular function | 88.6 | 1.11e-17 |
| peptidoglycan binding | Hs | molecular function | 88.6 | 1.11e-17 |
| sequence-specific DNA binding | Hs | molecular function | 88.6 | 1.11e-17 |
| inflammasome complex | Hs | cellular component | 88.6 | 1.11e-17 |
| NLRP3 inflammasome complex | Hs | cellular component | 88.6 | 1.11e-17 |
GO (InterProScan)
1 result
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | Pfam | molecular function | 0.045 |
