IPR Term	Analysis	Definition
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Prot_kinase_dom	Pfam	Protein kinase domain
MAPK_ERK3/4	PRINTS	Mitogen-activated protein (MAP) kinase, ERK3/4
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
Tyr_kinase_AS	ProSitePatterns	Tyrosine-protein kinase, active site

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
DNA binding	Blast	molecular function
protein kinase activity	Orthology	molecular function
protein serine/threonine kinase activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
extracellular region	Blast	cellular component
intracellular	Orthology	cellular component
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Blast	cellular component
early endosome	Blast	cellular component
Golgi apparatus	Blast	cellular component
microtubule organizing center	Blast	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Blast	cellular component
focal adhesion	Blast	cellular component
protein phosphorylation	Orthology	biological process
cell cycle	Orthology	biological process
signal transduction	Orthology	biological process
transcription factor binding	Blast	molecular function
regulation of gene expression	Orthology	biological process
membrane	Blast	cellular component
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
transferase activity	Orthology	molecular function
protein kinase binding	Orthology	molecular function
axon	Blast	cellular component
intracellular signal transduction	Orthology	biological process
identical protein binding	Blast	molecular function
protein homodimerization activity	Orthology	molecular function
protein heterodimerization activity	Orthology	molecular function
extracellular exosome	Blast	cellular component
cellular response to organic substance	Orthology	biological process
neuron projection development	Orthology	biological process
positive regulation of catalytic activity	Blast	biological process
positive regulation of signal transduction	Blast	biological process
endosome	Blast	cellular component
cytoskeletal part	Blast	cellular component
microtubule cytoskeleton	Blast	cellular component
membrane raft	Blast	cellular component
plasma membrane region	Blast	cellular component
enzyme binding	Blast	molecular function
cell projection	Blast	cellular component
cytoplasmic part	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
lysosome	Blast	cellular component
vacuolar part	Blast	cellular component
endomembrane system	Blast	cellular component
intracellular organelle lumen	Blast	cellular component
neuronal cell body	Blast	cellular component
intracellular organelle part	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
MAPK cascade	Hs	biological process
nucleotide binding	Hs	molecular function
protein kinase activity	Hs	molecular function
protein serine/threonine kinase activity	Hs	molecular function
MAP kinase activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
intracellular	Hs	cellular component
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
protein phosphorylation	Hs	biological process
cell cycle	Hs	biological process
signal transduction	Hs	biological process
regulation of gene expression	Hs	biological process
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
transferase activity	Hs	molecular function
protein kinase binding	Hs	molecular function
septin cytoskeleton	Hs	cellular component
protein homodimerization activity	Hs	molecular function
protein heterodimerization activity	Hs	molecular function
positive regulation of dendritic spine development	Hs	biological process
cellular response to organic substance	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	261	4.06e-76
phosphotyrosine residue binding	Hs	molecular function	210	4.58e-61
DNA binding	Hs	molecular function	210	4.58e-61
protein kinase activity	Hs	molecular function	261	4.06e-76
protein serine/threonine kinase activity	Hs	molecular function	261	4.06e-76
MAP kinase activity	Hs	molecular function	261	4.06e-76
MAP kinase kinase activity	Hs	molecular function	210	4.58e-61
protein binding	Hs	molecular function	261	4.06e-76
ATP binding	Hs	molecular function	261	4.06e-76
extracellular region	Hs	cellular component	210	4.58e-61
intracellular	Hs	cellular component	250	2.33e-73
nucleus	Hs	cellular component	261	4.06e-76
nucleoplasm	Hs	cellular component	261	4.06e-76
cytoplasm	Hs	cellular component	261	4.06e-76
mitochondrion	Hs	cellular component	210	4.58e-61
early endosome	Hs	cellular component	210	4.58e-61
late endosome	Hs	cellular component	210	4.58e-61
Golgi apparatus	Hs	cellular component	210	4.58e-61
microtubule organizing center	Hs	cellular component	210	4.58e-61
spindle	Hs	cellular component	210	4.58e-61
cytosol	Hs	cellular component	261	4.06e-76
cytoskeleton	Hs	cellular component	210	4.58e-61
plasma membrane	Hs	cellular component	210	4.58e-61
caveola	Hs	cellular component	210	4.58e-61
focal adhesion	Hs	cellular component	210	4.58e-61
transcription factor binding	Hs	molecular function	210	4.58e-61
RNA polymerase II carboxy-terminal domain kinase activity	Hs	molecular function	210	4.58e-61
membrane	Hs	cellular component	210	4.58e-61
kinase activity	Hs	molecular function	261	4.06e-76
transferase activity	Hs	molecular function	261	4.06e-76
protein kinase binding	Hs	molecular function	261	4.06e-76
phosphatase binding	Hs	molecular function	210	4.58e-61
axon	Hs	cellular component	210	4.58e-61
pseudopodium	Hs	cellular component	210	4.58e-61
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function	210	4.58e-61
septin cytoskeleton	Hs	cellular component	261	4.06e-76
dendrite cytoplasm	Hs	cellular component	210	4.58e-61
azurophil granule lumen	Hs	cellular component	210	4.58e-61
identical protein binding	Hs	molecular function	210	4.58e-61
protein homodimerization activity	Hs	molecular function	250	2.33e-73
perikaryon	Hs	cellular component	210	4.58e-61
protein heterodimerization activity	Hs	molecular function	261	4.06e-76
extracellular exosome	Hs	cellular component	210	4.58e-61
mitotic spindle	Hs	cellular component	210	4.58e-61
ficolin-1-rich granule lumen	Hs	cellular component	210	4.58e-61

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	1.9E-51
MAP kinase activity	PRINTS	molecular function	6.5E-6
ATP binding	Pfam	molecular function	1.9E-51
protein phosphorylation	Pfam	biological process	1.9E-51