IPR Term	Analysis	Definition
D-isomer_DH_CS1	ProSitePatterns	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
D-isomer_2_OHA_DH_cat_dom	Pfam	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NAD(P)-bd_dom_sf	SUPERFAMILY	NAD(P)-binding domain superfamily
D-isomer_DH_CS	ProSitePatterns	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site
D-isomer_DH_NAD-bd	Pfam	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
transcription corepressor activity	Blast	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
protein phosphorylation	Orthology	biological process
protein C-terminus binding	Orthology	molecular function
transcription factor binding	Orthology	molecular function
metabolic process	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
protein kinase binding	Blast	molecular function
cell junction	Blast	cellular component
cell differentiation	Orthology	biological process
protein homodimerization activity	Orthology	molecular function
myelin sheath	Blast	cellular component
macromolecular complex binding	Blast	molecular function
synapse	Blast	cellular component
negative regulation of transcription, DNA-templated	Orthology	biological process
oxidation-reduction process	Orthology	biological process
extracellular exosome	Blast	cellular component
intracellular part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
catalytic activity	Orthology	molecular function
organelle organization	Orthology	biological process
cellular protein modification process	Orthology	biological process
nucleotide binding	Orthology	molecular function
coenzyme binding	Orthology	molecular function
cell cycle	Orthology	biological process
cellular metabolic process	Blast	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
RNA polymerase II transcription corepressor activity	Hs	molecular function
transcription factor activity, sequence-specific DNA binding	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
transcription factor complex	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
protein phosphorylation	Hs	biological process
protein C-terminus binding	Hs	molecular function
transcription factor binding	Hs	molecular function
metabolic process	Hs	biological process
negative regulation of cell proliferation	Hs	biological process
viral process	Hs	biological process
oxidoreductase activity	Hs	molecular function
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Hs	molecular function
hydroxypyruvate reductase activity	Hs	molecular function
transcriptional repressor complex	Hs	cellular component
viral genome replication	Hs	biological process
protein domain specific binding	Hs	molecular function
cell differentiation	Hs	biological process
glyoxylate reductase (NADP) activity	Hs	molecular function
positive regulation of histone deacetylation	Hs	biological process
negative regulation of histone acetylation	Hs	biological process
protein homodimerization activity	Hs	molecular function
negative regulation of transcription, DNA-templated	Hs	biological process
NAD binding	Hs	molecular function
regulation of cell cycle	Hs	biological process
oxidation-reduction process	Hs	biological process
repressing transcription factor binding	Hs	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA polymerase II transcription corepressor activity	Hs	molecular function	564	0.0
transcription factor activity, sequence-specific DNA binding	Hs	molecular function	564	0.0
transcription corepressor activity	Hs	molecular function	569	0.0
phosphoglycerate dehydrogenase activity	Hs	molecular function	127	9.65e-32
protein binding	Hs	molecular function	569	0.0
nucleus	Hs	cellular component	569	0.0
nucleoplasm	Hs	cellular component	564	0.0
transcription factor complex	Hs	cellular component	564	0.0
cytoplasm	Hs	cellular component	564	0.0
cytosol	Hs	cellular component	569	0.0
protein C-terminus binding	Hs	molecular function	564	0.0
transcription factor binding	Hs	molecular function	564	0.0
electron carrier activity	Hs	molecular function	127	9.65e-32
oxidoreductase activity	Hs	molecular function	569	0.0
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Hs	molecular function	569	0.0
hydroxypyruvate reductase activity	Hs	molecular function	569	0.0
transcriptional repressor complex	Hs	cellular component	569	0.0
protein kinase binding	Hs	molecular function	569	0.0
protein domain specific binding	Hs	molecular function	564	0.0
cell junction	Hs	cellular component	569	0.0
L-malate dehydrogenase activity	Hs	molecular function	127	9.65e-32
glyoxylate reductase (NADP) activity	Hs	molecular function	569	0.0
protein homodimerization activity	Hs	molecular function	569	0.0
myelin sheath	Hs	cellular component	127	9.65e-32
macromolecular complex binding	Hs	molecular function	569	0.0
synapse	Hs	cellular component	569	0.0
NAD binding	Hs	molecular function	569	0.0
extracellular exosome	Hs	cellular component	127	9.65e-32
repressing transcription factor binding	Hs	molecular function	564	0.0

GO Term	Analysis	Type	e-value
metabolic process	Pfam	biological process	8.4E-25
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Pfam	molecular function	8.4E-25
NAD binding	Pfam	molecular function	6.8E-55
oxidation-reduction process	Pfam	biological process	6.8E-55