IPR Term	Analysis	Definition
LDrepeatLR_classA_rpt	ProSiteProfiles	Low-density lipoprotein (LDL) receptor class A repeat
LDLR_classB_rpt	ProSiteProfiles	LDLR class B repeat
LDrepeatLR_classA_rpt	CDD	Low-density lipoprotein (LDL) receptor class A repeat
EGF-like_dom	SMART	EGF-like domain
LDL_receptor-like_sf	SUPERFAMILY	LDL receptor-like superfamily
6-blade_b-propeller_TolB-like	Gene3D	Six-bladed beta-propeller, TolB-like
LDrepeatLR_classA_rpt	PRINTS	Low-density lipoprotein (LDL) receptor class A repeat
LDrepeatLR_classA_rpt	Pfam	Low-density lipoprotein (LDL) receptor class A repeat
LDLR_classB_rpt	SMART	LDLR class B repeat
LDLR_classB_rpt	Pfam	LDLR class B repeat
LDrepeatLR_classA_rpt	SMART	Low-density lipoprotein (LDL) receptor class A repeat

GO Term	Annotation Origin	Type
receptor binding	Orthology	molecular function
calcium ion binding	Blast	molecular function
protein binding	Orthology	molecular function
extracellular region	Orthology	cellular component
early endosome	Orthology	cellular component
endoplasmic reticulum	Orthology	cellular component
Golgi apparatus	Orthology	cellular component
plasma membrane	Orthology	cellular component
regulation of transcription, DNA-templated	Orthology	biological process
chemical synaptic transmission	Orthology	biological process
multicellular organism development	Orthology	biological process
cell surface	Orthology	cellular component
membrane	Orthology	cellular component
integral component of membrane	Orthology	cellular component
cell differentiation	Orthology	biological process
cytoplasmic vesicle	Orthology	cellular component
identical protein binding	Orthology	molecular function
protein homodimerization activity	Orthology	molecular function
neuronal cell body	Orthology	cellular component
membrane raft	Orthology	cellular component
synapse	Orthology	cellular component
positive regulation of transcription, DNA-templated	Orthology	biological process
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
animal organ development	Orthology	biological process
anatomical structure development	Orthology	biological process
regulation of canonical Wnt signaling pathway	Orthology	biological process
negative regulation of canonical Wnt signaling pathway	Orthology	biological process
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
synaptic membrane	Blast	cellular component
vasculature development	Orthology	biological process
mitochondrion	Orthology	cellular component
positive regulation of cell proliferation	Orthology	biological process
regulation of apoptotic process	Orthology	biological process
anatomical structure formation involved in morphogenesis	Orthology	biological process
nervous system development	Orthology	biological process
protein phosphorylation	Orthology	biological process
heart development	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
membrane organization	Orthology	biological process
organelle organization	Orthology	biological process
macromolecular complex binding	Orthology	molecular function
plasma membrane region	Orthology	cellular component
regulation of catalytic activity	Orthology	biological process
protein kinase activity	Orthology	molecular function
cellular process	Orthology	biological process
cell	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
kinase activity	Orthology	molecular function
enzyme regulator activity	Orthology	molecular function
transmembrane transport	Orthology	biological process
brain development	Orthology	biological process
whole membrane	Orthology	cellular component
intracellular organelle part	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
transmembrane signaling receptor activity	Orthology	molecular function
macromolecular complex	Orthology	cellular component
response to organic substance	Orthology	biological process
cell cycle	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
head development	Orthology	biological process
neuron differentiation	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
signaling receptor activity	Orthology	molecular function
protein localization to membrane	Orthology	biological process
organic substance transport	Orthology	biological process
intracellular transport	Orthology	biological process
cell adhesion	Orthology	biological process
plasma membrane part	Orthology	cellular component
positive regulation of Wnt signaling pathway	Orthology	biological process
cell development	Orthology	biological process
developmental process	Orthology	biological process
cell migration	Orthology	biological process
cellular response to organic substance	Orthology	biological process
protein transport	Orthology	biological process
regulation of signaling	Orthology	biological process
blood vessel morphogenesis	Orthology	biological process
apoptotic process	Orthology	biological process
organelle	Blast	cellular component
postsynapse	Blast	cellular component
neuron part	Blast	cellular component
protein kinase binding	Blast	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
neural tube closure	Hs	biological process
negative regulation of protein phosphorylation	Hs	biological process
pericardium morphogenesis	Hs	biological process
low-density lipoprotein receptor activity	Hs	molecular function
receptor binding	Hs	molecular function
frizzled binding	Hs	molecular function
protein binding	Hs	molecular function
extracellular region	Hs	cellular component
early endosome	Hs	cellular component
endoplasmic reticulum	Hs	cellular component
Golgi apparatus	Hs	cellular component
plasma membrane	Hs	cellular component
caveola	Hs	cellular component
regulation of transcription, DNA-templated	Hs	biological process
negative regulation of protein kinase activity	Hs	biological process
endocytosis	Hs	biological process
positive regulation of cytosolic calcium ion concentration	Hs	biological process
chemical synaptic transmission	Hs	biological process
multicellular organism development	Hs	biological process
embryonic pattern specification	Hs	biological process
cell surface	Hs	cellular component
neural crest formation	Hs	biological process
neural crest cell differentiation	Hs	biological process
membrane	Hs	cellular component
integral component of membrane	Hs	cellular component
Wnt signaling pathway	Hs	biological process
Wnt-protein binding	Hs	molecular function
kinase inhibitor activity	Hs	molecular function
toxin transporter activity	Hs	molecular function
cerebellum morphogenesis	Hs	biological process
thalamus development	Hs	biological process
cerebral cortex development	Hs	biological process
midbrain-hindbrain boundary development	Hs	biological process
cytoplasmic vesicle	Hs	cellular component
early endosome membrane	Hs	cellular component
apolipoprotein binding	Hs	molecular function
identical protein binding	Hs	molecular function
protein homodimerization activity	Hs	molecular function
Wnt-activated receptor activity	Hs	molecular function
neuronal cell body	Hs	cellular component
receptor complex	Hs	cellular component
response to peptide hormone	Hs	biological process
Wnt signaling pathway involved in dorsal/ventral axis specification	Hs	biological process
membrane raft	Hs	cellular component
synapse	Hs	cellular component
positive regulation of cell cycle	Hs	biological process
positive regulation of transcription, DNA-templated	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
positive regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
palate development	Hs	biological process
convergent extension	Hs	biological process
embryonic retina morphogenesis in camera-type eye	Hs	biological process
canonical Wnt signaling pathway	Hs	biological process
face morphogenesis	Hs	biological process
regulation of canonical Wnt signaling pathway	Hs	biological process
dopaminergic neuron differentiation	Hs	biological process
negative regulation of protein serine/threonine kinase activity	Hs	biological process
coreceptor activity involved in Wnt signaling pathway	Hs	molecular function
protein localization to plasma membrane	Hs	biological process
primitive streak formation	Hs	biological process
negative regulation of canonical Wnt signaling pathway	Hs	biological process
receptor-mediated endocytosis involved in cholesterol transport	Hs	biological process
Wnt signaling pathway involved in somitogenesis	Hs	biological process
axis elongation involved in somitogenesis	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process
cell-cell adhesion	Hs	biological process
toxin transport	Hs	biological process
coreceptor activity involved in canonical Wnt signaling pathway	Hs	molecular function
Wnt-Frizzled-LRP5/6 complex	Hs	cellular component
Wnt signalosome	Hs	cellular component
positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Hs	biological process
gastrulation with mouth forming second	Hs	biological process
vasculature development	Hs	biological process
osteoblast development	Hs	biological process
mitochondrion	Hs	cellular component
glucose catabolic process	Hs	biological process
cholesterol metabolic process	Hs	biological process
regulation of blood pressure	Hs	biological process
positive regulation of cell proliferation	Hs	biological process
response to radiation	Hs	biological process
anterior/posterior pattern specification	Hs	biological process
somatic stem cell population maintenance	Hs	biological process
limb morphogenesis	Hs	biological process
cell migration involved in gastrulation	Hs	biological process
cholesterol homeostasis	Hs	biological process
regulation of apoptotic process	Hs	biological process
positive regulation of fat cell differentiation	Hs	biological process
negative regulation of osteoblast differentiation	Hs	biological process
positive regulation of mitotic nuclear division	Hs	biological process
bone remodeling	Hs	biological process
regulation of bone remodeling	Hs	biological process
anatomical structure regression	Hs	biological process
retina morphogenesis in camera-type eye	Hs	biological process
bone development	Hs	biological process
bone morphogenesis	Hs	biological process
adipose tissue development	Hs	biological process
regulation of insulin secretion involved in cellular response to glucose stimulus	Hs	biological process
retinal blood vessel morphogenesis	Hs	biological process
apoptotic process involved in blood vessel morphogenesis	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
low-density lipoprotein receptor activity	Hs	molecular function	559	8.26e-175
receptor binding	Hs	molecular function	559	8.26e-175
frizzled binding	Hs	molecular function	559	8.26e-175
calcium ion binding	Hs	molecular function	316	1.72e-88
protein binding	Hs	molecular function	559	8.26e-175
extracellular region	Hs	cellular component	559	8.26e-175
early endosome	Hs	cellular component	559	8.26e-175
endoplasmic reticulum	Hs	cellular component	559	8.26e-175
Golgi apparatus	Hs	cellular component	559	8.26e-175
plasma membrane	Hs	cellular component	559	8.26e-175
caveola	Hs	cellular component	559	8.26e-175
cell surface	Hs	cellular component	559	8.26e-175
postsynaptic density	Hs	cellular component	316	1.72e-88
membrane	Hs	cellular component	559	8.26e-175
integral component of membrane	Hs	cellular component	559	8.26e-175
flotillin complex	Hs	cellular component	316	1.72e-88
Wnt-protein binding	Hs	molecular function	559	8.26e-175
kinase inhibitor activity	Hs	molecular function	559	8.26e-175
toxin transporter activity	Hs	molecular function	559	8.26e-175
dendrite	Hs	cellular component	316	1.72e-88
receptor tyrosine kinase binding	Hs	molecular function	316	1.72e-88
cytoplasmic vesicle	Hs	cellular component	559	8.26e-175
neuromuscular junction	Hs	cellular component	316	1.72e-88
early endosome membrane	Hs	cellular component	559	8.26e-175
apolipoprotein binding	Hs	molecular function	559	8.26e-175
identical protein binding	Hs	molecular function	559	8.26e-175
protein homodimerization activity	Hs	molecular function	559	8.26e-175
Wnt-activated receptor activity	Hs	molecular function	559	8.26e-175
neuronal cell body	Hs	cellular component	559	8.26e-175
receptor complex	Hs	cellular component	559	8.26e-175
membrane raft	Hs	cellular component	559	8.26e-175
synapse	Hs	cellular component	559	8.26e-175
coreceptor activity involved in Wnt signaling pathway	Hs	molecular function	559	8.26e-175
synaptic membrane	Hs	cellular component	316	1.72e-88
scaffold protein binding	Hs	molecular function	316	1.72e-88
coreceptor activity involved in canonical Wnt signaling pathway	Hs	molecular function	559	8.26e-175
Wnt-Frizzled-LRP5/6 complex	Hs	cellular component	559	8.26e-175
Wnt signalosome	Hs	cellular component	559	8.26e-175

GO Term	Analysis	Type	e-value
protein binding	PRINTS	molecular function	2.2E-18