IPR Term	Analysis	Definition
Prot_kinase_dom	Pfam	Protein kinase domain
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
Prot_kinase_dom	SMART	Protein kinase domain
Tribbles/Ser_Thr_kinase_40	PANTHER	Pseudokinase tribbles family/serine-threonine-protein kinase 40
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily

GO Term	Annotation Origin	Type
negative regulation of transcription from RNA polymerase II promoter	Orthology	biological process
transcription corepressor activity	Orthology	molecular function
protein kinase activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleolus	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
cytoskeleton	Orthology	cellular component
plasma membrane	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
protein phosphorylation	Orthology	biological process
apoptotic process	Orthology	biological process
transcription factor binding	Orthology	molecular function
enzyme binding	Orthology	molecular function
protein kinase binding	Orthology	molecular function
ubiquitin protein ligase binding	Orthology	molecular function
nuclear membrane	Orthology	cellular component
response to lipopolysaccharide	Orthology	biological process
negative regulation of transcription, DNA-templated	Orthology	biological process
negative regulation of nucleic acid-templated transcription	Orthology	biological process
enzyme regulator activity	Orthology	molecular function
regulation of catalytic activity	Orthology	biological process
cellular response to stress	Orthology	biological process
intracellular signal transduction	Orthology	biological process
organic substance metabolic process	Orthology	biological process
proteolysis	Orthology	biological process
cellular response to organic substance	Orthology	biological process
regulation of cellular metabolic process	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
regulation of signal transduction	Orthology	biological process
regulation of molecular function	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
immune system process	Orthology	biological process
animal organ development	Orthology	biological process
cell differentiation	Orthology	biological process
negative regulation of cell proliferation	Orthology	biological process
positive regulation of catalytic activity	Orthology	biological process
ubiquitin-protein transferase activity	Orthology	molecular function
negative regulation of signal transduction	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
negative regulation of transcription from RNA polymerase II promoter	Hs	biological process
transcription corepressor activity	Hs	molecular function
protein kinase activity	Hs	molecular function
protein kinase inhibitor activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
nucleus	Hs	cellular component
nucleolus	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
cytoskeleton	Hs	cellular component
plasma membrane	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
protein phosphorylation	Hs	biological process
negative regulation of protein kinase activity	Hs	biological process
apoptotic process	Hs	biological process
JNK cascade	Hs	biological process
transcription factor binding	Hs	molecular function
regulation of lipid metabolic process	Hs	biological process
enzyme binding	Hs	molecular function
protein kinase binding	Hs	molecular function
mitogen-activated protein kinase kinase binding	Hs	molecular function
ubiquitin protein ligase binding	Hs	molecular function
nuclear membrane	Hs	cellular component
positive regulation of protein binding	Hs	biological process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Hs	biological process
response to lipopolysaccharide	Hs	biological process
cellular response to insulin stimulus	Hs	biological process
response to endoplasmic reticulum stress	Hs	biological process
regulation of MAP kinase activity	Hs	biological process
negative regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
negative regulation of neutrophil differentiation	Hs	biological process
negative regulation of fatty acid biosynthetic process	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
negative regulation of smooth muscle cell proliferation	Hs	biological process
positive regulation of ubiquitin-protein transferase activity	Hs	biological process
negative regulation of protein kinase B signaling	Hs	biological process
ubiquitin-protein transferase regulator activity	Hs	molecular function
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Hs	biological process
negative regulation of nucleic acid-templated transcription	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
transcription corepressor activity	Hs	molecular function	246	5.59e-78
protein kinase activity	Hs	molecular function	295	5.99e-98
protein kinase inhibitor activity	Hs	molecular function	295	5.99e-98
protein binding	Hs	molecular function	258	1.06e-82
ATP binding	Hs	molecular function	295	5.99e-98
nucleus	Hs	cellular component	295	5.99e-98
nucleolus	Hs	cellular component	246	5.59e-78
cytoplasm	Hs	cellular component	295	5.99e-98
cytosol	Hs	cellular component	246	5.59e-78
cytoskeleton	Hs	cellular component	295	5.99e-98
plasma membrane	Hs	cellular component	246	5.59e-78
transcription factor binding	Hs	molecular function	295	5.99e-98
enzyme binding	Hs	molecular function	246	5.59e-78
protein kinase binding	Hs	molecular function	246	5.59e-78
mitogen-activated protein kinase kinase binding	Hs	molecular function	295	5.99e-98
ubiquitin protein ligase binding	Hs	molecular function	295	5.99e-98
nuclear membrane	Hs	cellular component	246	5.59e-78
ubiquitin-protein transferase regulator activity	Hs	molecular function	295	5.99e-98

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	1.4E-34
ATP binding	Pfam	molecular function	1.4E-34
protein phosphorylation	Pfam	biological process	1.4E-34