IPR Term	Analysis	Definition
AhpD-like	SUPERFAMILY	AhpD-like
AhpD-like	Gene3D	AhpD-like
Sestrin	PANTHER	Sestrin
Sestrin	Pfam	Sestrin

GO Term	Annotation Origin	Type
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
cytosol	Orthology	cellular component
oxidation-reduction process	Orthology	biological process
nucleolus	Orthology	cellular component
regulation of cellular metabolic process	Orthology	biological process
protein phosphorylation	Orthology	biological process
guanyl ribonucleotide binding	Orthology	molecular function
anion binding	Orthology	molecular function
GTPase regulator activity	Orthology	molecular function
purine ribonucleoside binding	Orthology	molecular function
organelle organization	Orthology	biological process
response to organic substance	Orthology	biological process
catalytic activity	Orthology	molecular function
cellular component organization	Orthology	biological process
intracellular signal transduction	Orthology	biological process
cellular response to DNA damage stimulus	Orthology	biological process
intracellular part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
DNA metabolic process	Orthology	biological process
cell communication	Orthology	biological process
cellular response to stress	Orthology	biological process
response to oxidative stress	Orthology	biological process
organic substance transport	Orthology	biological process
transmembrane transport	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
regulation of signal transduction	Orthology	biological process
cellular response to organic substance	Orthology	biological process
cation binding	Orthology	molecular function
small molecule binding	Orthology	molecular function
cellular metabolic process	Orthology	biological process
protein localization to organelle	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
cytoplasmic part	Orthology	cellular component
regulation of catalytic activity	Orthology	biological process
molecular transducer activity	Orthology	molecular function
protein serine/threonine kinase activity	Orthology	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
fibrillar center	Hs	cellular component
regulation of protein phosphorylation	Hs	biological process
GDP-dissociation inhibitor activity	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
cytosol	Hs	cellular component
fatty acid beta-oxidation	Hs	biological process
mitochondrion organization	Hs	biological process
response to glucose	Hs	biological process
positive regulation of macroautophagy	Hs	biological process
oxidoreductase activity	Hs	molecular function
oxidoreductase activity, acting on peroxide as acceptor	Hs	molecular function
negative regulation of cell growth	Hs	biological process
DNA damage response, signal transduction by p53 class mediator	Hs	biological process
nucleotide-activated protein kinase complex	Hs	cellular component
TORC2 complex	Hs	cellular component
mitochondrial DNA metabolic process	Hs	biological process
sulfiredoxin activity	Hs	molecular function
response to insulin	Hs	biological process
cellular response to amino acid starvation	Hs	biological process
cellular response to oxidative stress	Hs	biological process
TORC2 signaling	Hs	biological process
cellular response to glucose starvation	Hs	biological process
glucose homeostasis	Hs	biological process
protein kinase B signaling	Hs	biological process
glucose import	Hs	biological process
regulation of insulin receptor signaling pathway	Hs	biological process
regulation of protein kinase B signaling	Hs	biological process
peroxiredoxin activity	Hs	molecular function
oxidation-reduction process	Hs	biological process
GATOR2 complex	Hs	cellular component
triglyceride homeostasis	Hs	biological process
leucine binding	Hs	molecular function
cellular response to amino acid stimulus	Hs	biological process
reactive oxygen species metabolic process	Hs	biological process
cellular oxidant detoxification	Hs	biological process
positive regulation of protein localization to nucleus	Hs	biological process
regulation of response to reactive oxygen species	Hs	biological process
negative regulation of TORC1 signaling	Hs	biological process
cellular response to leucine starvation	Hs	biological process
ATG1/ULK1 kinase complex	Hs	cellular component
regulation of cAMP-dependent protein kinase activity	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
fibrillar center	Hs	cellular component	283	4.00e-86
GDP-dissociation inhibitor activity	Hs	molecular function	282	1.44e-86
protein binding	Hs	molecular function	306	7.76e-96
nucleus	Hs	cellular component	306	7.76e-96
cytoplasm	Hs	cellular component	306	7.76e-96
mitochondrion	Hs	cellular component	282	1.44e-86
cytosol	Hs	cellular component	283	4.00e-86
oxidoreductase activity	Hs	molecular function	306	7.76e-96
oxidoreductase activity, acting on peroxide as acceptor	Hs	molecular function	282	1.44e-86
nucleotide-activated protein kinase complex	Hs	cellular component	282	1.44e-86
TORC2 complex	Hs	cellular component	306	7.76e-96
sulfiredoxin activity	Hs	molecular function	282	1.44e-86
peroxiredoxin activity	Hs	molecular function	283	4.00e-86
GATOR2 complex	Hs	cellular component	306	7.76e-96
leucine binding	Hs	molecular function	283	4.00e-86
ATG1/ULK1 kinase complex	Hs	cellular component	282	1.44e-86

GO Term	Analysis	Type	e-value
nucleus	Pfam	cellular component	9.4E-169
regulation of response to reactive oxygen species	Pfam	biological process	9.4E-169