IPR Term	Analysis	Definition
Alkaline_phosphatase_core_sf	SUPERFAMILY	Alkaline-phosphatase-like, core domain superfamily
Sulfatase_N	Pfam	Sulfatase, N-terminal
Alkaline_Pase-like_a/b/a	Gene3D	Alkaline phosphatase-like, alpha/beta/alpha
Sulfatase_CS	ProSitePatterns	Sulfatase, conserved site

GO Term	Annotation Origin	Type
catalytic activity	Orthology	molecular function
calcium ion binding	Orthology	molecular function
protein binding	Blast	molecular function
extracellular region	Blast	cellular component
extracellular space	Orthology	cellular component
lysosome	Blast	cellular component
endoplasmic reticulum	Orthology	cellular component
Golgi apparatus	Orthology	cellular component
plasma membrane	Orthology	cellular component
apoptotic process	Orthology	biological process
metabolic process	Orthology	biological process
response to wounding	Orthology	biological process
cell surface	Orthology	cellular component
hydrolase activity	Orthology	molecular function
positive regulation of Wnt signaling pathway	Orthology	biological process
membrane raft	Orthology	cellular component
metal ion binding	Orthology	molecular function
extracellular exosome	Blast	cellular component
positive regulation of canonical Wnt signaling pathway	Orthology	biological process
animal organ development	Orthology	biological process
cell development	Orthology	biological process
Golgi apparatus part	Orthology	cellular component
angiogenesis	Orthology	biological process
protein metabolic process	Orthology	biological process
cell migration	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
regulation of transcription from RNA polymerase II promoter	Orthology	biological process
cellular response to organic substance	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
extracellular matrix organization	Orthology	biological process
regulation of signal transduction	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
system development	Orthology	biological process
cytoplasmic vesicle	Blast	cellular component
vacuolar part	Blast	cellular component
endomembrane system	Blast	cellular component
intracellular organelle lumen	Blast	cellular component
intracellular organelle part	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
kidney development	Hs	biological process
chondrocyte development	Hs	biological process
glomerular filtration	Hs	biological process
catalytic activity	Hs	molecular function
arylsulfatase activity	Hs	molecular function
calcium ion binding	Hs	molecular function
extracellular space	Hs	cellular component
endoplasmic reticulum	Hs	cellular component
Golgi apparatus	Hs	cellular component
Golgi stack	Hs	cellular component
plasma membrane	Hs	cellular component
apoptotic process	Hs	biological process
metabolic process	Hs	biological process
N-acetylglucosamine-6-sulfatase activity	Hs	molecular function
sulfuric ester hydrolase activity	Hs	molecular function
response to wounding	Hs	biological process
cell surface	Hs	cellular component
positive regulation of vascular endothelial growth factor production	Hs	biological process
negative regulation of angiogenesis	Hs	biological process
hydrolase activity	Hs	molecular function
positive regulation of Wnt signaling pathway	Hs	biological process
heparan sulfate proteoglycan metabolic process	Hs	biological process
negative regulation of cell migration	Hs	biological process
positive regulation of BMP signaling pathway	Hs	biological process
glomerular basement membrane development	Hs	biological process
regulation of fibroblast growth factor receptor signaling pathway	Hs	biological process
negative regulation of fibroblast growth factor receptor signaling pathway	Hs	biological process
membrane raft	Hs	cellular component
metal ion binding	Hs	molecular function
vascular endothelial growth factor receptor signaling pathway	Hs	biological process
embryonic skeletal system development	Hs	biological process
cartilage development	Hs	biological process
bone development	Hs	biological process
positive regulation of canonical Wnt signaling pathway	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
catalytic activity	Hs	molecular function	483	4.09e-160
arylsulfatase activity	Hs	molecular function	483	4.09e-160
calcium ion binding	Hs	molecular function	483	4.09e-160
protein binding	Hs	molecular function	309	1.16e-96
extracellular region	Hs	cellular component	309	1.16e-96
extracellular space	Hs	cellular component	483	4.09e-160
lysosome	Hs	cellular component	309	1.16e-96
endoplasmic reticulum	Hs	cellular component	483	4.09e-160
Golgi apparatus	Hs	cellular component	483	4.09e-160
Golgi stack	Hs	cellular component	483	4.09e-160
plasma membrane	Hs	cellular component	483	4.09e-160
N-acetylglucosamine-6-sulfatase activity	Hs	molecular function	483	4.09e-160
sulfuric ester hydrolase activity	Hs	molecular function	483	4.09e-160
cell surface	Hs	cellular component	483	4.09e-160
hydrolase activity	Hs	molecular function	483	4.09e-160
azurophil granule lumen	Hs	cellular component	309	1.16e-96
lysosomal lumen	Hs	cellular component	309	1.16e-96
membrane raft	Hs	cellular component	483	4.09e-160
metal ion binding	Hs	molecular function	483	4.09e-160
extracellular exosome	Hs	cellular component	309	1.16e-96
ficolin-1-rich granule lumen	Hs	cellular component	309	1.16e-96

GO Term	Analysis	Type	e-value
catalytic activity	SUPERFAMILY	molecular function	1.44E-89
metabolic process	SUPERFAMILY	biological process	1.44E-89
sulfuric ester hydrolase activity	Pfam	molecular function	6.8E-53