Gene Card
Best human hits
NLRP3; NOD1; NOD2
Species
Unique Gene ID
Phmamm.g00018629
Gene Model ID
Phmamm.CG.MTP2014.S4966.g18629
Location
S4966:840..2590
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.
Click here to see the tree inference method
InterPro
2 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Leu-rich_rpt | Pfam | Leucine-rich repeat |
| LRR_dom_sf | Gene3D | Leucine-rich repeat domain superfamily |
GOSlim
31 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| nucleotide binding | Blast | molecular function |
| actin binding | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| extracellular region | Blast | cellular component |
| nucleus | Blast | cellular component |
| cytoplasm | Blast | cellular component |
| mitochondrion | Blast | cellular component |
| endoplasmic reticulum | Blast | cellular component |
| Golgi apparatus | Blast | cellular component |
| cytosol | Blast | cellular component |
| cytoskeleton | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| transcription factor binding | Blast | molecular function |
| cell surface | Blast | cellular component |
| membrane | Blast | cellular component |
| basolateral plasma membrane | Blast | cellular component |
| apical plasma membrane | Blast | cellular component |
| enzyme binding | Blast | molecular function |
| protein kinase binding | Blast | molecular function |
| vesicle | Blast | cellular component |
| macromolecular complex | Blast | cellular component |
| identical protein binding | Blast | molecular function |
| protein homodimerization activity | Blast | molecular function |
| sequence-specific DNA binding | Blast | molecular function |
| nuclear part | Blast | cellular component |
| endopeptidase activity | Blast | molecular function |
| enzyme activator activity | Blast | molecular function |
| positive regulation of hydrolase activity | Blast | biological process |
| positive regulation of apoptotic process | Blast | biological process |
| carbohydrate derivative binding | Blast | molecular function |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
34 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| nucleotide binding | Hs | molecular function | 63.5 | 1.01e-11 |
| actin binding | Hs | molecular function | 63.5 | 1.01e-11 |
| protein binding | Hs | molecular function | 63.5 | 1.01e-11 |
| ATP binding | Hs | molecular function | 63.5 | 1.01e-11 |
| extracellular region | Hs | cellular component | 57.8 | 8.94e-10 |
| nucleus | Hs | cellular component | 57.8 | 8.94e-10 |
| cytoplasm | Hs | cellular component | 63.5 | 1.01e-11 |
| mitochondrion | Hs | cellular component | 63.5 | 1.01e-11 |
| endoplasmic reticulum | Hs | cellular component | 57.8 | 8.94e-10 |
| Golgi apparatus | Hs | cellular component | 63.5 | 1.01e-11 |
| cytosol | Hs | cellular component | 63.5 | 1.01e-11 |
| cytoskeleton | Hs | cellular component | 63.5 | 1.01e-11 |
| plasma membrane | Hs | cellular component | 63.5 | 1.01e-11 |
| transcription factor binding | Hs | molecular function | 57.8 | 8.94e-10 |
| COP9 signalosome | Hs | cellular component | 63.5 | 1.01e-11 |
| cysteine-type endopeptidase activator activity involved in apoptotic process | Hs | molecular function | 52.4 | 5.34e-08 |
| cell surface | Hs | cellular component | 63.5 | 1.01e-11 |
| membrane | Hs | cellular component | 63.5 | 1.01e-11 |
| basolateral plasma membrane | Hs | cellular component | 63.5 | 1.01e-11 |
| apical plasma membrane | Hs | cellular component | 52.4 | 5.34e-08 |
| enzyme binding | Hs | molecular function | 63.5 | 1.01e-11 |
| protein kinase binding | Hs | molecular function | 63.5 | 1.01e-11 |
| Hsp70 protein binding | Hs | molecular function | 63.5 | 1.01e-11 |
| vesicle | Hs | cellular component | 63.5 | 1.01e-11 |
| muramyl dipeptide binding | Hs | molecular function | 63.5 | 1.01e-11 |
| macromolecular complex | Hs | cellular component | 63.5 | 1.01e-11 |
| identical protein binding | Hs | molecular function | 57.8 | 8.94e-10 |
| protein homodimerization activity | Hs | molecular function | 52.4 | 5.34e-08 |
| peptidoglycan binding | Hs | molecular function | 63.5 | 1.01e-11 |
| sequence-specific DNA binding | Hs | molecular function | 57.8 | 8.94e-10 |
| CARD domain binding | Hs | molecular function | 63.5 | 1.01e-11 |
| Hsp90 protein binding | Hs | molecular function | 63.5 | 1.01e-11 |
| inflammasome complex | Hs | cellular component | 57.8 | 8.94e-10 |
| NLRP3 inflammasome complex | Hs | cellular component | 57.8 | 8.94e-10 |
GO (InterProScan)
1 result
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein binding | Pfam | molecular function | 6.5E-4 |
