Gene Card
Best human hits
ANAPC2; CUL1; CUL4B
Species
Unique Gene ID
Phmamm.g00010639
Gene Model ID
Phmamm.CG.MTP2014.S620.g10639
Location
S620:86751..98100
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Cullin_homology_sf | SUPERFAMILY | Cullin homology domain superfamily |
APC_su2_C | SMART | Anaphase-promoting complex subunit 2, C-terminal |
APC_su2_C | Pfam | Anaphase-promoting complex subunit 2, C-terminal |
WH_DNA-bd_sf | SUPERFAMILY | Winged helix DNA-binding domain superfamily |
WH-like_DNA-bd_sf | Gene3D | Winged helix-like DNA-binding domain superfamily |
Cullin_homology | SMART | Cullin homology domain |
Cullin_N | Pfam | Cullin, N-terminal |
Cullin_homology | ProSiteProfiles | Cullin homology domain |
GO Term | Annotation Origin | Type |
---|---|---|
protein polyubiquitination | Orthology | biological process |
ubiquitin-protein transferase activity | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
cell cycle | Orthology | biological process |
nervous system development | Orthology | biological process |
protein ubiquitination | Orthology | biological process |
cell differentiation | Orthology | biological process |
ubiquitin protein ligase binding | Orthology | molecular function |
cell division | Orthology | biological process |
extracellular exosome | Blast | cellular component |
nuclear part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
proteolysis | Orthology | biological process |
axonogenesis | Orthology | biological process |
cell morphogenesis involved in neuron differentiation | Orthology | biological process |
neuron projection morphogenesis | Orthology | biological process |
DNA binding | Blast | molecular function |
intracellular part | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
anaphase-promoting complex | Hs | cellular component |
cytosol | Hs | cellular component |
ubiquitin-dependent protein catabolic process | Hs | biological process |
cell cycle | Hs | biological process |
nervous system development | Hs | biological process |
protein ubiquitination | Hs | biological process |
cell differentiation | Hs | biological process |
anaphase-promoting complex-dependent catabolic process | Hs | biological process |
ubiquitin protein ligase binding | Hs | molecular function |
proteasome-mediated ubiquitin-dependent protein catabolic process | Hs | biological process |
positive regulation of axon extension | Hs | biological process |
positive regulation of dendrite morphogenesis | Hs | biological process |
cell division | Hs | biological process |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | Hs | biological process |
ubiquitin protein ligase activity | Hs | molecular function |
protein K11-linked ubiquitination | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
damaged DNA binding | Hs | molecular function | 53.9 | 2.99e-07 |
ubiquitin-protein transferase activity | Hs | molecular function | 60.1 | 3.63e-09 |
protein binding | Hs | molecular function | 416 | 3.66e-134 |
nucleus | Hs | cellular component | 416 | 3.66e-134 |
nucleoplasm | Hs | cellular component | 416 | 3.66e-134 |
anaphase-promoting complex | Hs | cellular component | 416 | 3.66e-134 |
cytosol | Hs | cellular component | 416 | 3.66e-134 |
SCF ubiquitin ligase complex | Hs | cellular component | 60.1 | 3.63e-09 |
cullin-RING ubiquitin ligase complex | Hs | cellular component | 60.1 | 3.63e-09 |
Cul4B-RING E3 ubiquitin ligase complex | Hs | cellular component | 53.9 | 2.99e-07 |
ubiquitin protein ligase binding | Hs | molecular function | 416 | 3.66e-134 |
ubiquitin protein ligase activity | Hs | molecular function | 416 | 3.66e-134 |
extracellular exosome | Hs | cellular component | 53.9 | 2.99e-07 |
Cul4-RING E3 ubiquitin ligase complex | Hs | cellular component | 53.9 | 2.99e-07 |
Parkin-FBXW7-Cul1 ubiquitin ligase complex | Hs | cellular component | 60.1 | 3.63e-09 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
ubiquitin-dependent protein catabolic process | Pfam | biological process | 2.8E-25 |
ubiquitin protein ligase binding | Pfam | molecular function | 2.8E-25 |