IPR Term	Analysis	Definition
PPM-type_dom_sf	Gene3D	PPM-type phosphatase domain superfamily
PPM-type_dom_sf	SUPERFAMILY	PPM-type phosphatase domain superfamily
PPM-type_phosphatase_dom	Pfam	PPM-type phosphatase domain
PPM-type_phosphatase_dom	SMART	PPM-type phosphatase domain
PPM-type_phosphatase_dom	CDD	PPM-type phosphatase domain
PPM-type_phosphatase_dom	ProSiteProfiles	PPM-type phosphatase domain
PP2C	PANTHER	Protein phosphatase 2C family

GO Term	Annotation Origin	Type
magnesium ion binding	Blast	molecular function
catalytic activity	Orthology	molecular function
protein binding	Orthology	molecular function
cytosol	Orthology	cellular component
protein dephosphorylation	Orthology	biological process
enzyme activator activity	Orthology	molecular function
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
nuclear speck	Orthology	cellular component
hydrolase activity	Orthology	molecular function
metal ion binding	Blast	molecular function
positive regulation of catalytic activity	Orthology	biological process
intracellular signal transduction	Orthology	biological process
protein serine/threonine kinase activity	Orthology	molecular function
positive regulation of signal transduction	Orthology	biological process
signal transduction	Orthology	biological process
innate immune response	Orthology	biological process
anatomical structure morphogenesis	Orthology	biological process
heart development	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
cellular response to organic substance	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
cellular response to stress	Orthology	biological process
protein phosphorylation	Orthology	biological process
intracellular organelle part	Orthology	cellular component
whole membrane	Orthology	cellular component
endosome	Orthology	cellular component
bounding membrane of organelle	Orthology	cellular component
peptidase activity, acting on L-amino acid peptides	Orthology	molecular function
animal organ development	Orthology	biological process
blood vessel development	Orthology	biological process
immune response	Orthology	biological process
protein kinase binding	Orthology	molecular function
cytokine-mediated signaling pathway	Orthology	biological process
transition metal ion binding	Blast	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
activation of MAPKKK activity	Hs	biological process
activation of MAPK activity	Hs	biological process
MyD88-dependent toll-like receptor signaling pathway	Hs	biological process
heart morphogenesis	Hs	biological process
catalytic activity	Hs	molecular function
protein serine/threonine phosphatase activity	Hs	molecular function
protein binding	Hs	molecular function
cytosol	Hs	cellular component
protein dephosphorylation	Hs	biological process
transforming growth factor beta receptor signaling pathway	Hs	biological process
I-kappaB kinase/NF-kappaB signaling	Hs	biological process
JNK cascade	Hs	biological process
enzyme activator activity	Hs	molecular function
endosome membrane	Hs	cellular component
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
protein deubiquitination	Hs	biological process
nuclear speck	Hs	cellular component
kinase activator activity	Hs	molecular function
lung development	Hs	biological process
aorta development	Hs	biological process
Fc-epsilon receptor signaling pathway	Hs	biological process
positive regulation of MAP kinase activity	Hs	biological process
mitogen-activated protein kinase p38 binding	Hs	molecular function
positive regulation of NF-kappaB transcription factor activity	Hs	biological process
coronary vasculature development	Hs	biological process
interleukin-1-mediated signaling pathway	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
magnesium ion binding	Hs	molecular function	42.7	4.15e-04
catalytic activity	Hs	molecular function	308	3.29e-99
phosphoprotein phosphatase activity	Hs	molecular function	42.7	4.15e-04
protein serine/threonine phosphatase activity	Hs	molecular function	308	3.29e-99
protein binding	Hs	molecular function	308	3.29e-99
cytosol	Hs	cellular component	308	3.29e-99
enzyme activator activity	Hs	molecular function	308	3.29e-99
endosome membrane	Hs	cellular component	308	3.29e-99
kinase activity	Hs	molecular function	308	3.29e-99
nuclear speck	Hs	cellular component	308	3.29e-99
hydrolase activity	Hs	molecular function	42.7	4.15e-04
kinase activator activity	Hs	molecular function	308	3.29e-99
manganese ion binding	Hs	molecular function	42.7	4.15e-04
metal ion binding	Hs	molecular function	42.7	4.15e-04
mitogen-activated protein kinase p38 binding	Hs	molecular function	308	3.29e-99

GO Term	Analysis	Type	e-value
catalytic activity	Pfam	molecular function	2.2E-12
protein serine/threonine phosphatase activity	PANTHER	molecular function	3.7E-107
protein dephosphorylation	PANTHER	biological process	3.7E-107