Gene Card
Best human hits
KLHL12; KLHL4; RIPK1
Species
Unique Gene ID
Phmamm.g00011018
Gene Model ID
Phmamm.CG.MTP2014.S661.g11018
Location
S661:29790..33659
Transcript Models and Sequences
n/a
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Click here to see the tree inference method
InterPro
9 results
| IPR Term | Analysis | Definition |
|---|---|---|
| Prot_kinase_dom | Pfam | Protein kinase domain |
| Ser/Thr_kinase_AS | ProSitePatterns | Serine/threonine-protein kinase, active site |
| Gal_Oxase/kelch_b-propeller | SUPERFAMILY | Galactose oxidase/kelch, beta-propeller |
| Kelch_1 | Pfam | Kelch repeat type 1 |
| Kinase-like_dom_sf | SUPERFAMILY | Protein kinase-like domain superfamily |
| Kelch-typ_b-propeller | Gene3D | Kelch-type beta propeller |
| Kelch_1 | SMART | Kelch repeat type 1 |
| Prot_kinase_dom | ProSiteProfiles | Protein kinase domain |
| Prot_kinase_dom | SMART | Protein kinase domain |
GOSlim
36 results
| GO Term | Annotation Origin | Type |
|---|---|---|
| Golgi membrane | Blast | cellular component |
| nucleotide binding | Blast | molecular function |
| actin binding | Blast | molecular function |
| protein kinase activity | Blast | molecular function |
| protein serine/threonine kinase activity | Blast | molecular function |
| ubiquitin-protein transferase activity | Blast | molecular function |
| signal transducer activity | Blast | molecular function |
| protein binding | Blast | molecular function |
| ATP binding | Blast | molecular function |
| cytoplasm | Blast | cellular component |
| mitochondrion | Blast | cellular component |
| microtubule organizing center | Blast | cellular component |
| cytosol | Blast | cellular component |
| cytoskeleton | Blast | cellular component |
| plasma membrane | Blast | cellular component |
| protein phosphorylation | InterProScan | biological process |
| microtubule cytoskeleton | Blast | cellular component |
| membrane | Blast | cellular component |
| kinase activity | Blast | molecular function |
| transferase activity | Blast | molecular function |
| cytoplasmic vesicle | Blast | cellular component |
| ubiquitin protein ligase binding | Blast | molecular function |
| identical protein binding | Blast | molecular function |
| intracellular membrane-bounded organelle | Blast | cellular component |
| macromolecular complex binding | Blast | molecular function |
| membrane raft | Blast | cellular component |
| receptor binding | Blast | molecular function |
| intracellular organelle part | Blast | cellular component |
| whole membrane | Blast | cellular component |
| endosome | Blast | cellular component |
| bounding membrane of organelle | Blast | cellular component |
| membrane part | Blast | cellular component |
| macromolecular complex | Blast | cellular component |
| endomembrane system | Blast | cellular component |
| plasma membrane part | Blast | cellular component |
| intracellular part | Blast | cellular component |
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
|---|
GO (Blast)
34 results
| GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
|---|---|---|---|---|
| Golgi membrane | Hs | cellular component | 110 | 1.58e-25 |
| nucleotide binding | Hs | molecular function | 106 | 4.78e-24 |
| actin binding | Hs | molecular function | 100 | 5.38e-22 |
| protein kinase activity | Hs | molecular function | 106 | 4.78e-24 |
| protein serine/threonine kinase activity | Hs | molecular function | 106 | 4.78e-24 |
| ubiquitin-protein transferase activity | Hs | molecular function | 110 | 1.58e-25 |
| signal transducer activity | Hs | molecular function | 106 | 4.78e-24 |
| death receptor binding | Hs | molecular function | 106 | 4.78e-24 |
| protein binding | Hs | molecular function | 110 | 1.58e-25 |
| ATP binding | Hs | molecular function | 106 | 4.78e-24 |
| cytoplasm | Hs | cellular component | 106 | 4.78e-24 |
| mitochondrion | Hs | cellular component | 106 | 4.78e-24 |
| microtubule organizing center | Hs | cellular component | 110 | 1.58e-25 |
| cytosol | Hs | cellular component | 110 | 1.58e-25 |
| cytoskeleton | Hs | cellular component | 100 | 5.38e-22 |
| plasma membrane | Hs | cellular component | 106 | 4.78e-24 |
| endosome membrane | Hs | cellular component | 106 | 4.78e-24 |
| microtubule cytoskeleton | Hs | cellular component | 100 | 5.38e-22 |
| membrane | Hs | cellular component | 106 | 4.78e-24 |
| kinase activity | Hs | molecular function | 106 | 4.78e-24 |
| transferase activity | Hs | molecular function | 106 | 4.78e-24 |
| COPII vesicle coat | Hs | cellular component | 110 | 1.58e-25 |
| COPII-coated ER to Golgi transport vesicle | Hs | cellular component | 110 | 1.58e-25 |
| death-inducing signaling complex | Hs | cellular component | 106 | 4.78e-24 |
| cytoplasmic vesicle | Hs | cellular component | 110 | 1.58e-25 |
| Cul3-RING ubiquitin ligase complex | Hs | cellular component | 110 | 1.58e-25 |
| ubiquitin protein ligase binding | Hs | molecular function | 106 | 4.78e-24 |
| identical protein binding | Hs | molecular function | 110 | 1.58e-25 |
| intracellular membrane-bounded organelle | Hs | cellular component | 110 | 1.58e-25 |
| receptor complex | Hs | cellular component | 106 | 4.78e-24 |
| macromolecular complex binding | Hs | molecular function | 106 | 4.78e-24 |
| membrane raft | Hs | cellular component | 106 | 4.78e-24 |
| death domain binding | Hs | molecular function | 106 | 4.78e-24 |
| ripoptosome | Hs | cellular component | 106 | 4.78e-24 |
GO (InterProScan)
4 results
| GO Term | Analysis | Type | e-value |
|---|---|---|---|
| protein kinase activity | Pfam | molecular function | 9.0E-31 |
| protein binding | Gene3D | molecular function | 1.9E-32 |
| ATP binding | Pfam | molecular function | 9.0E-31 |
| protein phosphorylation | Pfam | biological process | 9.0E-31 |
