Gene Card
Best human hits
IDH3A; IDH3B; IDH3G
Species
Unique Gene ID
Phmamm.g00011340
Gene Model ID
Phmamm.CG.MTP2014.S702.g11340
Location
S702:54557..55667
Transcript Models and Sequences
AHC0AAA20YM23
Plate: Plate_20_M23
AHC0AAA21YO11
Plate: Plate_21_O11
AHC0AAA24YL11
Plate: Plate_24_L11
AHC0AAA3YJ19
Plate: Plate_3_J19
AHC0AAA35YO24
Plate: Plate_35_O24
AHC0AAA53YD14
Plate: Plate_53_D14
AHC0AAA65YM18
Plate: Plate_65_M18
AHC0AAA71YP20
Plate: Plate_71_P20
AHC0AAA77YD21
Plate: Plate_77_D21
AHC0AAA102YD21
Plate: Plate_102_D21
AHC0AAA109YH17
Plate: Plate_109_H17
AHC0AAA112YJ11
Plate: Plate_112_J11
AHC0AAA121YG23
Plate: Plate_121_G23
AHC0AAA129YB19
Plate: Plate_129_B19
AHC0AAA133YJ23
Plate: Plate_133_J23
AHC0AAA136YE22
Plate: Plate_136_E22
AHC0AAA141YC04
Plate: Plate_141_C04
AHC0AAA142YG20
Plate: Plate_142_G20
AHC0AAA145YI23
Plate: Plate_145_I23
AHC0AAA85YF21
Plate: Plate_85_F21
AHC0AAA95YD14
Plate: Plate_95_D14
AHC0AAA133YJ21
Plate: Plate_133_J21
AHC0AAA160YN19
Plate: Plate_160_N19
AHC0AAA169YH04
Plate: Plate_169_H04
AHC0AAA190YM22
Plate: Plate_190_M22
AHC0AAA204YG02
Plate: Plate_204_G02
AHC0AAA205YD10
Plate: Plate_205_D10
AHC0AAA207YM19
Plate: Plate_207_M19
AHC0AAA207YP18
Plate: Plate_207_P18
AHC0AAA208YM03
Plate: Plate_208_M03
AHC0AAA211YO13
Plate: Plate_211_O13
AHC0AAA230YH16
Plate: Plate_230_H16
AHC0AAA231YF23
Plate: Plate_231_F23
AHC0AAA241YJ04
Plate: Plate_241_J04
AHC0AAA243YG04
Plate: Plate_243_G04
n/a
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IPR Term | Analysis | Definition |
---|---|---|
IsoPropMal-DH-like_dom | SMART | Isopropylmalate dehydrogenase-like domain |
IsoCit/isopropylmalate_DH_CS | ProSitePatterns | Isocitrate/isopropylmalate dehydrogenase, conserved site |
IsoPropMal-DH-like_dom | Pfam | Isopropylmalate dehydrogenase-like domain |
Isocitrate_DH_NAD | TIGRFAM | Isocitrate dehydrogenase NAD-dependent |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
magnesium ion binding | Orthology | molecular function |
ATP binding | Blast | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Blast | cellular component |
nucleolus | Blast | cellular component |
mitochondrion | Orthology | cellular component |
mitochondrial matrix | Orthology | cellular component |
myelin sheath | Orthology | cellular component |
metal ion binding | Orthology | molecular function |
oxidation-reduction process | Orthology | biological process |
catalytic activity | Orthology | molecular function |
organic substance metabolic process | Orthology | biological process |
cellular metabolic process | Orthology | biological process |
coenzyme binding | Orthology | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
magnesium ion binding | Hs | molecular function |
isocitrate dehydrogenase (NAD+) activity | Hs | molecular function |
nucleus | Hs | cellular component |
mitochondrion | Hs | cellular component |
mitochondrial matrix | Hs | cellular component |
carbohydrate metabolic process | Hs | biological process |
tricarboxylic acid cycle | Hs | biological process |
oxidoreductase activity | Hs | molecular function |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Hs | molecular function |
myelin sheath | Hs | cellular component |
metal ion binding | Hs | molecular function |
NAD binding | Hs | molecular function |
oxidation-reduction process | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 283 | 8.97e-93 |
magnesium ion binding | Hs | molecular function | 581 | 0.0 |
isocitrate dehydrogenase (NAD+) activity | Hs | molecular function | 581 | 0.0 |
ATP binding | Hs | molecular function | 283 | 8.97e-93 |
nucleus | Hs | cellular component | 581 | 0.0 |
nucleoplasm | Hs | cellular component | 283 | 8.97e-93 |
nucleolus | Hs | cellular component | 283 | 8.97e-93 |
mitochondrion | Hs | cellular component | 581 | 0.0 |
mitochondrial matrix | Hs | cellular component | 581 | 0.0 |
electron carrier activity | Hs | molecular function | 280 | 1.14e-91 |
oxidoreductase activity | Hs | molecular function | 581 | 0.0 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | Hs | molecular function | 581 | 0.0 |
myelin sheath | Hs | cellular component | 581 | 0.0 |
metal ion binding | Hs | molecular function | 581 | 0.0 |
NAD binding | Hs | molecular function | 581 | 0.0 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
magnesium ion binding | ProSitePatterns | molecular function | |
isocitrate dehydrogenase (NAD+) activity | TIGRFAM | molecular function | 1.8E-149 |
tricarboxylic acid cycle | TIGRFAM | biological process | 1.8E-149 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | SMART | molecular function | 1.4E-168 |
NAD binding | ProSitePatterns | molecular function | |
oxidation-reduction process | SMART | biological process | 1.4E-168 |