IPR Term	Analysis	Definition
Argonaute_N	Pfam	Protein argonaute, N-terminal
PAZ_dom	SMART	PAZ domain
PAZ_dom	ProSiteProfiles	PAZ domain
Piwi	ProSiteProfiles	Piwi domain
PAZ_dom_sf	SUPERFAMILY	PAZ domain superfamily
RNaseH_sf	Gene3D	Ribonuclease H superfamily
ArgoL1	Pfam	Argonaute, linker 1 domain
Piwi	Pfam	Piwi domain
Argonaute_Mid_dom	Pfam	Protein argonaute, Mid domain
RNaseH-like_sf	SUPERFAMILY	Ribonuclease H-like superfamily
PAZ_dom	Pfam	PAZ domain
ArgoL2	Pfam	Argonaute linker 2 domain
Piwi	SMART	Piwi domain
ArgoL1	SMART	Argonaute, linker 1 domain

GO Term	Annotation Origin	Type
nuclear-transcribed mRNA catabolic process	Orthology	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Orthology	molecular function
nucleic acid binding	Orthology	molecular function
RNA binding	Orthology	molecular function
protein binding	Orthology	molecular function
nucleus	Orthology	cellular component
nucleoplasm	Orthology	cellular component
cytoplasm	Orthology	cellular component
cytosol	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
mRNA catabolic process	Orthology	biological process
translational initiation	Orthology	biological process
protein C-terminus binding	Orthology	molecular function
positive regulation of gene expression	Orthology	biological process
membrane	Orthology	cellular component
hydrolase activity	Orthology	molecular function
cell junction	Orthology	cellular component
transcription regulatory region DNA binding	Orthology	molecular function
positive regulation of transcription from RNA polymerase II promoter	Orthology	biological process
metal ion binding	Orthology	molecular function
extracellular exosome	Orthology	cellular component
nuclear body	Orthology	cellular component
negative regulation of apoptotic process	Orthology	biological process
intracellular non-membrane-bounded organelle	Orthology	cellular component
nuclear lumen	Orthology	cellular component
cytoplasmic part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
enzyme binding	Orthology	molecular function
regulation of gene expression	Orthology	biological process
RNA metabolic process	Orthology	biological process
intracellular part	Orthology	cellular component
cell surface receptor signaling pathway	Orthology	biological process
cell-cell signaling	Orthology	biological process
multicellular organism development	Orthology	biological process
angiogenesis	Orthology	biological process
RNA processing	Orthology	biological process
negative regulation of gene expression	Orthology	biological process
cellular process	Orthology	biological process
regulation of cell proliferation	Orthology	biological process
cell division	Orthology	biological process
cell migration	Orthology	biological process
reproductive process	Orthology	biological process
male gamete generation	Orthology	biological process
animal organ development	Orthology	biological process
cell morphogenesis	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
RNA 7-methylguanosine cap binding	Hs	molecular function
condensed nuclear chromosome	Hs	cellular component
P-body	Hs	cellular component
nuclear-transcribed mRNA catabolic process	Hs	biological process
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function
RNA polymerase II core binding	Hs	molecular function
core promoter binding	Hs	molecular function
nucleic acid binding	Hs	molecular function
RNA binding	Hs	molecular function
double-stranded RNA binding	Hs	molecular function
single-stranded RNA binding	Hs	molecular function
mRNA binding	Hs	molecular function
translation initiation factor activity	Hs	molecular function
nuclease activity	Hs	molecular function
endonuclease activity	Hs	molecular function
endoribonuclease activity	Hs	molecular function
protein binding	Hs	molecular function
nucleus	Hs	cellular component
nucleoplasm	Hs	cellular component
cytoplasm	Hs	cellular component
cytosol	Hs	cellular component
polysome	Hs	cellular component
mRNA cap binding complex	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
mRNA catabolic process	Hs	biological process
translation	Hs	biological process
translational initiation	Hs	biological process
regulation of translation	Hs	biological process
Wnt signaling pathway, calcium modulating pathway	Hs	biological process
protein C-terminus binding	Hs	molecular function
post-embryonic development	Hs	biological process
RNA secondary structure unwinding	Hs	biological process
miRNA metabolic process	Hs	biological process
positive regulation of gene expression	Hs	biological process
membrane	Hs	cellular component
RISC complex	Hs	cellular component
negative regulation of angiogenesis	Hs	biological process
hydrolase activity	Hs	molecular function
cell junction	Hs	cellular component
production of siRNA involved in RNA interference	Hs	biological process
dendrite	Hs	cellular component
intracellular ribonucleoprotein complex	Hs	cellular component
gene silencing by RNA	Hs	biological process
pre-miRNA processing	Hs	biological process
micro-ribonucleoprotein complex	Hs	cellular component
siRNA loading onto RISC involved in RNA interference	Hs	biological process
production of miRNAs involved in gene silencing by miRNA	Hs	biological process
siRNA binding	Hs	molecular function
miRNA binding	Hs	molecular function
miRNA mediated inhibition of translation	Hs	biological process
mRNA cleavage involved in gene silencing by miRNA	Hs	biological process
miRNA loading onto RISC involved in gene silencing by miRNA	Hs	biological process
cytoplasmic ribonucleoprotein granule	Hs	cellular component
transcription regulatory region DNA binding	Hs	molecular function
positive regulation of angiogenesis	Hs	biological process
positive regulation of transcription from RNA polymerase II promoter	Hs	biological process
negative regulation of translational initiation	Hs	biological process
metal ion binding	Hs	molecular function
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	Hs	biological process
regulation of gene silencing by miRNA	Hs	biological process
extracellular exosome	Hs	cellular component
endoribonuclease activity, cleaving siRNA-paired mRNA	Hs	molecular function
RISC-loading complex	Hs	cellular component
regulation of stem cell proliferation	Hs	biological process
RNA phosphodiester bond hydrolysis, endonucleolytic	Hs	biological process
endoribonuclease activity, cleaving miRNA-paired mRNA	Hs	molecular function
mRNA cap binding	Hs	molecular function
positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Hs	biological process
positive regulation of trophoblast cell migration	Hs	biological process
synaptonemal complex assembly	Hs	biological process
male meiotic nuclear division	Hs	biological process
male gonad development	Hs	biological process
nuclear body	Hs	cellular component
regulation of cell morphogenesis	Hs	biological process
negative regulation of apoptotic process	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
RNA 7-methylguanosine cap binding	Hs	molecular function	729	0.0
condensed nuclear chromosome	Hs	cellular component	727	0.0
P-body	Hs	cellular component	729	0.0
RNA polymerase II core promoter proximal region sequence-specific DNA binding	Hs	molecular function	719	0.0
RNA polymerase II core binding	Hs	molecular function	729	0.0
core promoter binding	Hs	molecular function	729	0.0
nucleic acid binding	Hs	molecular function	729	0.0
RNA binding	Hs	molecular function	729	0.0
double-stranded RNA binding	Hs	molecular function	729	0.0
single-stranded RNA binding	Hs	molecular function	729	0.0
mRNA binding	Hs	molecular function	729	0.0
translation initiation factor activity	Hs	molecular function	729	0.0
nuclease activity	Hs	molecular function	729	0.0
endonuclease activity	Hs	molecular function	729	0.0
endoribonuclease activity	Hs	molecular function	729	0.0
protein binding	Hs	molecular function	729	0.0
nucleus	Hs	cellular component	729	0.0
nucleoplasm	Hs	cellular component	729	0.0
cytoplasm	Hs	cellular component	729	0.0
cytosol	Hs	cellular component	729	0.0
polysome	Hs	cellular component	729	0.0
mRNA cap binding complex	Hs	cellular component	729	0.0
protein C-terminus binding	Hs	molecular function	729	0.0
membrane	Hs	cellular component	729	0.0
RISC complex	Hs	cellular component	729	0.0
hydrolase activity	Hs	molecular function	729	0.0
cell junction	Hs	cellular component	729	0.0
dendrite	Hs	cellular component	729	0.0
intracellular ribonucleoprotein complex	Hs	cellular component	729	0.0
micro-ribonucleoprotein complex	Hs	cellular component	729	0.0
siRNA binding	Hs	molecular function	729	0.0
miRNA binding	Hs	molecular function	729	0.0
cytoplasmic ribonucleoprotein granule	Hs	cellular component	727	0.0
transcription regulatory region DNA binding	Hs	molecular function	719	0.0
metal ion binding	Hs	molecular function	729	0.0
extracellular exosome	Hs	cellular component	729	0.0
endoribonuclease activity, cleaving siRNA-paired mRNA	Hs	molecular function	729	0.0
RISC-loading complex	Hs	cellular component	729	0.0
endoribonuclease activity, cleaving miRNA-paired mRNA	Hs	molecular function	729	0.0
mRNA cap binding	Hs	molecular function	729	0.0

GO Term	Analysis	Type	e-value
nucleic acid binding	Gene3D	molecular function	2.5E-130
protein binding	SUPERFAMILY	molecular function	5.18E-64