IPR Term	Analysis	Definition
Gprotein_alpha_su	PANTHER	Guanine nucleotide binding protein (G-protein), alpha subunit
GproteinA_insert	Gene3D	G protein alpha subunit, helical insertion
Gprotein_alpha_S	PRINTS	G-protein alpha subunit, group S
Gprotein_alpha_su	CDD	Guanine nucleotide binding protein (G-protein), alpha subunit
P-loop_NTPase	SUPERFAMILY	P-loop containing nucleoside triphosphate hydrolase
Gprotein_alpha_su	PRINTS	Guanine nucleotide binding protein (G-protein), alpha subunit
GproteinA_insert	SUPERFAMILY	G protein alpha subunit, helical insertion
Gprotein_alpha_su	SMART	Guanine nucleotide binding protein (G-protein), alpha subunit
Gprotein_alpha_su	Pfam	Guanine nucleotide binding protein (G-protein), alpha subunit

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
GTPase activity	Orthology	molecular function
signal transducer activity	Orthology	molecular function
protein binding	Blast	molecular function
GTP binding	Orthology	molecular function
extracellular region	Blast	cellular component
nucleus	Blast	cellular component
cytoplasm	Blast	cellular component
lysosomal membrane	Blast	cellular component
cytosol	Blast	cellular component
plasma membrane	Orthology	cellular component
signal transduction	Orthology	biological process
G-protein coupled receptor signaling pathway	Orthology	biological process
regulation of signal transduction	Orthology	biological process
membrane	Blast	cellular component
apical plasma membrane	Blast	cellular component
guanyl nucleotide binding	Orthology	molecular function
intrinsic component of membrane	Blast	cellular component
cytoplasmic vesicle	Blast	cellular component
cell projection	Blast	cellular component
metal ion binding	Orthology	molecular function
perinuclear region of cytoplasm	Blast	cellular component
extracellular exosome	Orthology	cellular component
receptor binding	Orthology	molecular function
intracellular part	Orthology	cellular component
plasma membrane part	Orthology	cellular component
macromolecular complex	Orthology	cellular component
regulation of catalytic activity	Orthology	biological process
intracellular signal transduction	Orthology	biological process
negative regulation of signal transduction	Orthology	biological process
sensory perception	Orthology	biological process
macromolecular complex binding	Orthology	molecular function
plasma membrane region	Blast	cellular component
cell leading edge	Blast	cellular component
organelle part	Blast	cellular component
cell projection part	Blast	cellular component
neuron projection	Blast	cellular component
endomembrane system	Blast	cellular component
Golgi membrane	Blast	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
nucleotide binding	Hs	molecular function
G-protein coupled receptor binding	Hs	molecular function
GTPase activity	Hs	molecular function
signal transducer activity	Hs	molecular function
GTP binding	Hs	molecular function
heterotrimeric G-protein complex	Hs	cellular component
plasma membrane	Hs	cellular component
signal transduction	Hs	biological process
G-protein coupled receptor signaling pathway	Hs	biological process
adenylate cyclase-activating G-protein coupled receptor signaling pathway	Hs	biological process
activation of adenylate cyclase activity	Hs	biological process
adenylate cyclase-activating dopamine receptor signaling pathway	Hs	biological process
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	Hs	biological process
sensory perception of smell	Hs	biological process
guanyl nucleotide binding	Hs	molecular function
G-protein beta/gamma-subunit complex binding	Hs	molecular function
metal ion binding	Hs	molecular function
extracellular exosome	Hs	cellular component

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	547	0.0
G-protein coupled receptor binding	Hs	molecular function	533	0.0
ruffle	Hs	cellular component	547	0.0
photoreceptor outer segment	Hs	cellular component	279	1.17e-91
GTPase activity	Hs	molecular function	547	0.0
signal transducer activity	Hs	molecular function	547	0.0
insulin-like growth factor receptor binding	Hs	molecular function	547	0.0
protein binding	Hs	molecular function	547	0.0
GTP binding	Hs	molecular function	547	0.0
extracellular region	Hs	cellular component	547	0.0
nucleus	Hs	cellular component	547	0.0
cytoplasm	Hs	cellular component	547	0.0
lysosomal membrane	Hs	cellular component	279	1.17e-91
cytosol	Hs	cellular component	547	0.0
heterotrimeric G-protein complex	Hs	cellular component	547	0.0
plasma membrane	Hs	cellular component	547	0.0
membrane	Hs	cellular component	547	0.0
apical plasma membrane	Hs	cellular component	547	0.0
guanyl nucleotide binding	Hs	molecular function	547	0.0
transport vesicle	Hs	cellular component	547	0.0
dendrite	Hs	cellular component	547	0.0
intrinsic component of membrane	Hs	cellular component	547	0.0
cytoplasmic vesicle	Hs	cellular component	547	0.0
G-protein beta/gamma-subunit complex binding	Hs	molecular function	547	0.0
beta-2 adrenergic receptor binding	Hs	molecular function	547	0.0
D1 dopamine receptor binding	Hs	molecular function	547	0.0
type 2A serotonin receptor binding	Hs	molecular function	279	1.17e-91
mu-type opioid receptor binding	Hs	molecular function	547	0.0
trans-Golgi network membrane	Hs	cellular component	547	0.0
ionotropic glutamate receptor binding	Hs	molecular function	547	0.0
cell projection	Hs	cellular component	547	0.0
metal ion binding	Hs	molecular function	547	0.0
perinuclear region of cytoplasm	Hs	cellular component	547	0.0
corticotropin-releasing hormone receptor 1 binding	Hs	molecular function	547	0.0
extracellular exosome	Hs	cellular component	547	0.0

GO Term	Analysis	Type	e-value
GTPase activity	PANTHER	molecular function	2.3E-196
signal transducer activity	PANTHER	molecular function	2.3E-196
GTP binding	PRINTS	molecular function	4.5E-26
signal transduction	Gene3D	biological process	2.2E-137
G-protein coupled receptor signaling pathway	PANTHER	biological process	2.3E-196
guanyl nucleotide binding	PANTHER	molecular function	2.3E-196
G-protein beta/gamma-subunit complex binding	PANTHER	molecular function	2.3E-196