Gene Card
Best human hits
CD33; EXOSC4; EXOSC5
Species
Unique Gene ID
Phmamm.g00002809
Gene Model ID
Phmamm.CG.MTP2014.S84.g02809
Location
S84:226895..228475
Transcript Models and Sequences
AHC0AAA79YE11
Plate: Plate_79_E11
AHC0AAA144YL22
Plate: Plate_144_L22
AHC0AAA180YK23
Plate: Plate_180_K23
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
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You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
PNPase/RNase_PH_dom_sf | Gene3D | PNPase/RNase PH domain superfamily |
ExoRNase_PH_dom1 | Pfam | Exoribonuclease, phosphorolytic domain 1 |
Ribosomal_S5_D2-typ_fold | SUPERFAMILY | Ribosomal protein S5 domain 2-type fold |
GO Term | Annotation Origin | Type |
---|---|---|
nuclear-transcribed mRNA catabolic process | Orthology | biological process |
RNA binding | Orthology | molecular function |
protein binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
nucleolus | Orthology | cellular component |
cytoplasm | Orthology | cellular component |
cytosol | Orthology | cellular component |
plasma membrane | Blast | cellular component |
integral component of plasma membrane | Blast | cellular component |
RNA catabolic process | Orthology | biological process |
membrane | Blast | cellular component |
integral component of membrane | Blast | cellular component |
extracellular exosome | Blast | cellular component |
RNA metabolic process | Orthology | biological process |
hydrolase activity | Orthology | molecular function |
nuclear lumen | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
cytoplasmic part | Orthology | cellular component |
intracellular part | Orthology | cellular component |
RNA processing | Orthology | biological process |
intracellular organelle part | Orthology | cellular component |
intracellular non-membrane-bounded organelle | Orthology | cellular component |
mRNA catabolic process | Orthology | biological process |
immune system process | Orthology | biological process |
defense response | Orthology | biological process |
plasma membrane part | Blast | cellular component |
cell surface | Blast | cellular component |
binding | Blast | molecular function |
whole membrane | Blast | cellular component |
cytoplasmic vesicle | Blast | cellular component |
endomembrane system | Blast | cellular component |
bounding membrane of organelle | Blast | cellular component |
cytoskeleton | Blast | cellular component |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
3'-5'-exoribonuclease activity | Hs | molecular function |
nuclear exosome (RNase complex) | Hs | cellular component |
cytoplasmic exosome (RNase complex) | Hs | cellular component |
exosome (RNase complex) | Hs | cellular component |
RNA binding | Hs | molecular function |
protein binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
nucleolus | Hs | cellular component |
cytoplasm | Hs | cellular component |
cytosol | Hs | cellular component |
rRNA processing | Hs | biological process |
RNA catabolic process | Hs | biological process |
rRNA catabolic process | Hs | biological process |
rRNA 3'-end processing | Hs | biological process |
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' | Hs | biological process |
U4 snRNA 3'-end processing | Hs | biological process |
transcriptionally active chromatin | Hs | cellular component |
regulation of mRNA stability | Hs | biological process |
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | Hs | biological process |
defense response to virus | Hs | biological process |
nuclear mRNA surveillance | Hs | biological process |
polyadenylation-dependent snoRNA 3'-end processing | Hs | biological process |
RNA phosphodiester bond hydrolysis, exonucleolytic | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
3'-5'-exoribonuclease activity | Hs | molecular function | 149 | 1.76e-45 |
nuclear exosome (RNase complex) | Hs | cellular component | 149 | 1.76e-45 |
cytoplasmic exosome (RNase complex) | Hs | cellular component | 149 | 1.76e-45 |
exosome (RNase complex) | Hs | cellular component | 149 | 1.76e-45 |
RNA binding | Hs | molecular function | 149 | 1.76e-45 |
receptor activity | Hs | molecular function | 35.8 | 0.008 |
protein binding | Hs | molecular function | 149 | 1.76e-45 |
nucleus | Hs | cellular component | 149 | 1.76e-45 |
nucleoplasm | Hs | cellular component | 149 | 1.76e-45 |
nucleolus | Hs | cellular component | 149 | 1.76e-45 |
cytoplasm | Hs | cellular component | 149 | 1.76e-45 |
cytosol | Hs | cellular component | 149 | 1.76e-45 |
plasma membrane | Hs | cellular component | 35.8 | 0.008 |
integral component of plasma membrane | Hs | cellular component | 35.8 | 0.008 |
external side of plasma membrane | Hs | cellular component | 35.8 | 0.008 |
membrane | Hs | cellular component | 35.8 | 0.008 |
integral component of membrane | Hs | cellular component | 35.8 | 0.008 |
AU-rich element binding | Hs | molecular function | 42.7 | 3.57e-05 |
carbohydrate binding | Hs | molecular function | 35.8 | 0.008 |
transcriptionally active chromatin | Hs | cellular component | 149 | 1.76e-45 |
specific granule membrane | Hs | cellular component | 35.8 | 0.008 |
intermediate filament cytoskeleton | Hs | cellular component | 42.7 | 3.57e-05 |
extracellular exosome | Hs | cellular component | 35.8 | 0.008 |
tertiary granule membrane | Hs | cellular component | 35.8 | 0.008 |
GO Term | Analysis | Type | e-value |
---|