IPR Term	Analysis	Definition
Ser-Thr/Tyr_kinase_cat_dom	PRINTS	Serine-threonine/tyrosine-protein kinase, catalytic domain
Prot_kinase_dom	ProSiteProfiles	Protein kinase domain
SH3-like_dom_sf	SUPERFAMILY	SH3-like domain superfamily
Ser/Thr_kinase_AS	ProSitePatterns	Serine/threonine-protein kinase, active site
SH3_domain	ProSiteProfiles	SH3 domain
SH3_domain	SMART	SH3 domain
SH3_domain	PRINTS	SH3 domain
Protein_kinase_ATP_BS	ProSitePatterns	Protein kinase, ATP binding site
SH3_domain	Pfam	SH3 domain
Kinase-like_dom_sf	SUPERFAMILY	Protein kinase-like domain superfamily
Prot_kinase_dom	SMART	Protein kinase domain
Ser-Thr/Tyr_kinase_cat_dom	Pfam	Serine-threonine/tyrosine-protein kinase, catalytic domain

GO Term	Annotation Origin	Type
nucleotide binding	Orthology	molecular function
transcription corepressor activity	Orthology	molecular function
protein kinase activity	Orthology	molecular function
protein serine/threonine kinase activity	Orthology	molecular function
protein binding	Orthology	molecular function
ATP binding	Orthology	molecular function
intracellular	Orthology	cellular component
cytoplasm	Orthology	cellular component
centrosome	Orthology	cellular component
microtubule organizing center	Orthology	cellular component
cytoskeleton	Orthology	cellular component
microtubule	Orthology	cellular component
transcription, DNA-templated	Orthology	biological process
regulation of transcription, DNA-templated	Orthology	biological process
protein phosphorylation	Orthology	biological process
apoptotic process	Orthology	biological process
microtubule-based process	Orthology	biological process
signal transduction	Orthology	biological process
cell death	Orthology	biological process
cell proliferation	Orthology	biological process
membrane	Orthology	cellular component
kinase activity	Orthology	molecular function
phosphorylation	Orthology	biological process
transferase activity	Orthology	molecular function
identical protein binding	Orthology	molecular function
protein homodimerization activity	Orthology	molecular function
positive regulation of apoptotic process	Orthology	biological process
negative regulation of transcription, DNA-templated	Orthology	biological process
protein autophosphorylation	Orthology	biological process
intracellular signal transduction	Orthology	biological process
positive regulation of catalytic activity	Orthology	biological process
positive regulation of signal transduction	Orthology	biological process
cellular response to stress	Orthology	biological process
cell surface receptor signaling pathway	Orthology	biological process
protein kinase binding	Orthology	molecular function
transcription factor binding	Orthology	molecular function
regulation of molecular function	Orthology	biological process
transcription factor activity, sequence-specific DNA binding	Orthology	molecular function
enzyme binding	Orthology	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
MAPK cascade	Hs	biological process
nucleotide binding	Hs	molecular function
activation of MAPKK activity	Hs	biological process
activation of MAPK activity	Hs	biological process
transcription corepressor activity	Hs	molecular function
protein kinase activity	Hs	molecular function
protein serine/threonine kinase activity	Hs	molecular function
JUN kinase kinase kinase activity	Hs	molecular function
MAP kinase kinase activity	Hs	molecular function
MAP kinase kinase kinase activity	Hs	molecular function
protein tyrosine kinase activity	Hs	molecular function
protein binding	Hs	molecular function
ATP binding	Hs	molecular function
intracellular	Hs	cellular component
cytoplasm	Hs	cellular component
centrosome	Hs	cellular component
microtubule organizing center	Hs	cellular component
cytoskeleton	Hs	cellular component
microtubule	Hs	cellular component
transcription, DNA-templated	Hs	biological process
regulation of transcription, DNA-templated	Hs	biological process
protein phosphorylation	Hs	biological process
apoptotic process	Hs	biological process
microtubule-based process	Hs	biological process
signal transduction	Hs	biological process
smoothened signaling pathway	Hs	biological process
JNK cascade	Hs	biological process
activation of JNKK activity	Hs	biological process
activation of JUN kinase activity	Hs	biological process
cell death	Hs	biological process
cell proliferation	Hs	biological process
membrane	Hs	cellular component
kinase activity	Hs	molecular function
phosphorylation	Hs	biological process
transferase activity	Hs	molecular function
peptidyl-serine phosphorylation	Hs	biological process
peptidyl-threonine phosphorylation	Hs	biological process
peptidyl-tyrosine phosphorylation	Hs	biological process
mitogen-activated protein kinase kinase binding	Hs	molecular function
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function
identical protein binding	Hs	molecular function
protein homodimerization activity	Hs	molecular function
positive regulation of apoptotic process	Hs	biological process
bHLH transcription factor binding	Hs	molecular function
negative regulation of sequence-specific DNA binding transcription factor activity	Hs	biological process
positive regulation of JUN kinase activity	Hs	biological process
positive regulation of neuron apoptotic process	Hs	biological process
negative regulation of transcription, DNA-templated	Hs	biological process
positive regulation of JNK cascade	Hs	biological process
protein autophosphorylation	Hs	biological process
Rac GTPase binding	Hs	molecular function

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
nucleotide binding	Hs	molecular function	595	0.0
transcription corepressor activity	Hs	molecular function	555	1.04e-179
protein kinase activity	Hs	molecular function	595	0.0
protein serine/threonine kinase activity	Hs	molecular function	595	0.0
JUN kinase kinase kinase activity	Hs	molecular function	595	0.0
MAP kinase kinase activity	Hs	molecular function	595	0.0
MAP kinase kinase kinase activity	Hs	molecular function	595	0.0
protein tyrosine kinase activity	Hs	molecular function	595	0.0
protein binding	Hs	molecular function	595	0.0
ATP binding	Hs	molecular function	595	0.0
intracellular	Hs	cellular component	595	0.0
cytoplasm	Hs	cellular component	595	0.0
centrosome	Hs	cellular component	578	0.0
microtubule organizing center	Hs	cellular component	578	0.0
cytoskeleton	Hs	cellular component	578	0.0
microtubule	Hs	cellular component	578	0.0
membrane	Hs	cellular component	578	0.0
kinase activity	Hs	molecular function	595	0.0
transferase activity	Hs	molecular function	595	0.0
mitogen-activated protein kinase kinase binding	Hs	molecular function	578	0.0
mitogen-activated protein kinase kinase kinase binding	Hs	molecular function	578	0.0
identical protein binding	Hs	molecular function	578	0.0
protein homodimerization activity	Hs	molecular function	595	0.0
bHLH transcription factor binding	Hs	molecular function	555	1.04e-179
Rac GTPase binding	Hs	molecular function	578	0.0

GO Term	Analysis	Type	e-value
protein kinase activity	Pfam	molecular function	3.6E-65
protein binding	SUPERFAMILY	molecular function	3.54E-17
ATP binding	SMART	molecular function	2.5E-60
protein phosphorylation	Pfam	biological process	3.6E-65