Gene Card
Best human hits
DHX58; FANCM; IFIH1
Species
Unique Gene ID
Phmamm.g00012503
Gene Model ID
Phmamm.CG.MTP2014.S871.g12503
Location
S871:27566..34312
Transcript Models and Sequences
n/a
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The 'History' button on the left side permits you to see the changes you have made and eventually to go back.
You can Press 'Shift' Key + Left Mouse Click on the leaf's node to access to a gene card in a new window.
You can Press 'Ctrl' Key + Left Mouse Click on nodes to do a multiple selection.

IPR Term | Analysis | Definition |
---|---|---|
Helicase_C | ProSiteProfiles | Helicase, C-terminal |
Helicase_C | CDD | Helicase, C-terminal |
P-loop_NTPase | SUPERFAMILY | P-loop containing nucleoside triphosphate hydrolase |
Helicase_C | SMART | Helicase, C-terminal |
FANCM-MHF-bd | Pfam | Fanconi anemia group M protein, MHF binding domain |
Helicase_C | Pfam | Helicase, C-terminal |
GO Term | Annotation Origin | Type |
---|---|---|
nucleotide binding | Orthology | molecular function |
nucleic acid binding | Orthology | molecular function |
DNA binding | Orthology | molecular function |
chromatin binding | Orthology | molecular function |
RNA binding | Blast | molecular function |
protein binding | Orthology | molecular function |
ATP binding | Orthology | molecular function |
nucleus | Orthology | cellular component |
nucleoplasm | Orthology | cellular component |
cytoplasm | Blast | cellular component |
cytosol | Blast | cellular component |
DNA repair | Orthology | biological process |
cellular response to DNA damage stimulus | Orthology | biological process |
zinc ion binding | Blast | molecular function |
hydrolase activity | Orthology | molecular function |
identical protein binding | Blast | molecular function |
metal ion binding | Blast | molecular function |
reproductive process | Orthology | biological process |
DNA metabolic process | Orthology | biological process |
nucleoside-triphosphatase activity | Orthology | molecular function |
DNA replication | Orthology | biological process |
nucleoplasm part | Orthology | cellular component |
macromolecular complex | Orthology | cellular component |
macromolecular complex binding | Blast | molecular function |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type |
---|---|---|
nucleotide binding | Hs | molecular function |
resolution of meiotic recombination intermediates | Hs | biological process |
nucleic acid binding | Hs | molecular function |
DNA binding | Hs | molecular function |
chromatin binding | Hs | molecular function |
helicase activity | Hs | molecular function |
nuclease activity | Hs | molecular function |
protein binding | Hs | molecular function |
ATP binding | Hs | molecular function |
nucleus | Hs | cellular component |
nucleoplasm | Hs | cellular component |
DNA repair | Hs | biological process |
cellular response to DNA damage stimulus | Hs | biological process |
hydrolase activity | Hs | molecular function |
replication fork processing | Hs | biological process |
interstrand cross-link repair | Hs | biological process |
Fanconi anaemia nuclear complex | Hs | cellular component |
FANCM-MHF complex | Hs | cellular component |
nucleic acid phosphodiester bond hydrolysis | Hs | biological process |
GO Term | SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae |
Type | Score | E-value |
---|---|---|---|---|
nucleotide binding | Hs | molecular function | 439 | 2.20e-131 |
nucleic acid binding | Hs | molecular function | 439 | 2.20e-131 |
DNA binding | Hs | molecular function | 439 | 2.20e-131 |
chromatin binding | Hs | molecular function | 439 | 2.20e-131 |
RNA binding | Hs | molecular function | 60.8 | 3.51e-09 |
double-stranded RNA binding | Hs | molecular function | 60.8 | 3.51e-09 |
single-stranded RNA binding | Hs | molecular function | 60.8 | 3.51e-09 |
helicase activity | Hs | molecular function | 439 | 2.20e-131 |
nuclease activity | Hs | molecular function | 439 | 2.20e-131 |
protein binding | Hs | molecular function | 439 | 2.20e-131 |
ATP binding | Hs | molecular function | 439 | 2.20e-131 |
nucleus | Hs | cellular component | 439 | 2.20e-131 |
nucleoplasm | Hs | cellular component | 439 | 2.20e-131 |
cytoplasm | Hs | cellular component | 60.8 | 3.51e-09 |
cytosol | Hs | cellular component | 60.8 | 3.51e-09 |
zinc ion binding | Hs | molecular function | 60.8 | 3.51e-09 |
hydrolase activity | Hs | molecular function | 439 | 2.20e-131 |
identical protein binding | Hs | molecular function | 60.8 | 3.51e-09 |
ribonucleoprotein complex binding | Hs | molecular function | 60.8 | 3.51e-09 |
Fanconi anaemia nuclear complex | Hs | cellular component | 439 | 2.20e-131 |
metal ion binding | Hs | molecular function | 60.8 | 3.51e-09 |
FANCM-MHF complex | Hs | cellular component | 439 | 2.20e-131 |
GO Term | Analysis | Type | e-value |
---|---|---|---|
DNA repair | PANTHER | biological process | 3.8E-180 |