IPR Term	Analysis	Definition
Pyrroline-COOH_reductase	TIGRFAM	Pyrroline-5-carboxylate reductase
6-PGluconate_DH-like_C_sf	SUPERFAMILY	6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
P5CR_dimer	Pfam	Pyrroline-5-carboxylate reductase, dimerisation domain
Pyrroline-COOH_reductase	PIRSF	Pyrroline-5-carboxylate reductase
P5C_Rdtase_cat_N	Pfam	Pyrroline-5-carboxylate reductase, catalytic, N-terminal
Pyrroline-COOH_reductase	Hamap	Pyrroline-5-carboxylate reductase
NAD(P)-bd_dom_sf	SUPERFAMILY	NAD(P)-binding domain superfamily

GO Term	Annotation Origin	Type
protein binding	Orthology	molecular function
cytoplasm	Orthology	cellular component
mitochondrion	Orthology	cellular component
mitochondrial matrix	Orthology	cellular component
cytosol	Blast	cellular component
identical protein binding	Orthology	molecular function
oxidation-reduction process	Orthology	biological process
catalytic activity	Orthology	molecular function
cellular biosynthetic process	Orthology	biological process
cellular response to stress	Orthology	biological process
response to oxidative stress	Orthology	biological process
negative regulation of cell death	Orthology	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type
pyrroline-5-carboxylate reductase activity	Hs	molecular function
protein binding	Hs	molecular function
cytoplasm	Hs	cellular component
mitochondrion	Hs	cellular component
mitochondrial matrix	Hs	cellular component
proline biosynthetic process	Hs	biological process
cellular amino acid biosynthetic process	Hs	biological process
oxidoreductase activity	Hs	molecular function
cellular response to oxidative stress	Hs	biological process
identical protein binding	Hs	molecular function
regulation of mitochondrial membrane potential	Hs	biological process
oxidation-reduction process	Hs	biological process
L-proline biosynthetic process	Hs	biological process
negative regulation of hydrogen peroxide-induced cell death	Hs	biological process

GO Term	SpeciesCe = Caenorhabditis elegans Dr = Danio rerio Dm = Drosophila melanogaster Gg = Gallus gallus Hs = Homo sapiens Mm = Mus musculus Sc = Saccharomyces cerevisiae	Type	Score	E-value
pyrroline-5-carboxylate reductase activity	Hs	molecular function	333	5.02e-114
protein binding	Hs	molecular function	333	5.02e-114
cytoplasm	Hs	cellular component	328	1.83e-112
mitochondrion	Hs	cellular component	333	5.02e-114
mitochondrial matrix	Hs	cellular component	333	5.02e-114
cytosol	Hs	cellular component	239	4.23e-78
oxidoreductase activity	Hs	molecular function	333	5.02e-114
identical protein binding	Hs	molecular function	333	5.02e-114

GO Term	Analysis	Type	e-value
pyrroline-5-carboxylate reductase activity	PIRSF	molecular function	6.2E-80
proline biosynthetic process	PIRSF	biological process	6.2E-80
oxidation-reduction process	PIRSF	biological process	6.2E-80