- Transcript 'Phfumi.CG.MTP2014.S4...' >
- Transcript 'KH2012:KH.C4.484.v1....' >
- Transcript 'Phmamm.CG.MTP2014.S6...' >
- Transcript 'KH2012:KH.C1.25.v1.A...' >
- Transcript 'KH2012:KH.C1.695.v1....'
Transcript Model
Transcript Id
KH2012:KH.C1.695.v1.A.SL1-1
Possible name(s)
PIK3CA; PIK3CB; PIK3CD
Gene model
Location
KhC1 [3,272,704 / 3,290,553]
Amino acid sequence
Length: 1,070
>KH.C1.695.v1.A.SL1-1
AELSGMSISRAFSGVHLGGSGGAYDEEESIYDEWGYHNSMYVSVDFFLPTGIYIPIDIPR
NSTIKEVKNLLWQEAIHHPLFSKLLNPESYTFTYITSFGLPEEIVDESRHLSEFDIFHEL
PVLKLVQSRGNIAEKRVIQEINHLTCIKSNESRSFRKDMRELAAQACKDRDTLHWKSLLQ
RHFPPTIIPYLNESTHYLKDFGLIQLTSENSETVYTIKINPSWSTEHLTEVALQTWVSKT
KARLPSTNKDDYVLKGNGKEFIVGNHPIYMFKFLRKALVCKPPPVVSLVHVASVRKILPQ
QYQLLKKVQTNFAPPVPEKHRAVWSLWQLDVMFKLRIIRAGNVNAGQERDKKLVVHVGLY
HGTETLCPTTYTKEPVKEMAAGNEYQWDEECFFDINAVNLPRNAMLCLAICSSKRNVGGK
SKRKESTQKNTQHSASPIAWANMMVFDFKRYLKAGLYRLNCWQVNHDNLDSNNLSPRGGV
MLNPDVEQAAFIEIMMPEYQATIMYPSLPEVLEEAARQAVVRESNLMTRGASKSHMTQLD
EVVRKDRFDDLFDDDKSLLWRLRIDCREKYPEALSKVLASAKWNSYKSVAMVQAMLNSWT
PLSPERAMELLDCQFADEHVRDFAVKCLENLRDDELQQYLMQLVQVVKFDSYLNSSLVRF
ILRRAWSNRKIGHFLFWHLKAEISNTLLNLRFALIMEAYLYGNLPHVKTLYKQQEALNKM
RTLNERVRSEFSQKDIKVRARQALKDTANQDSFKEALTSVECPLEPNLDLEELLVEKCKV
MNSKMRPLWLVFKNKQVQDGSMSVIYKNGDDLRQDMLTLQTISIMDMLWKAEGLDLRMIP
YGCLATGKGTGMIEVVTHSNTIANIQKTRGGKMSAFRHQTLIEWLEQNNSTPSEFEQAIE
NFTYSCAGYCVATFVLGVGDRHSDNIMVTEKGQLFHIDFGHILGNFKTKFGIKRERVPFV
LAHDFVHVINKGKTNNKADFDQFRKLCDNAFCILRKKGYLIITLFALMLHSGLPEMTSLD
HLEYLRETLALHLTEQKALQQFRSKFNKALTDAWATSVNWFFHNVARDNT
Nucleotide sequence
Length: 3,648
>KH2012:KH.C1.695.v1.A.SL1-1
TTACAGAATTTCTAAGAGTGAACCTATAGACGTTGGAATGCGGCAACATAGGTTCTGACT
CTTCTGTAAGCTGAGTTATCAGGCATGAGTATTTCTCGTGCATTTTCAGGCGTCCACCTG
GGGGGAAGTGGAGGTGCTTATGACGAAGAGGAATCTATATATGATGAATGGGGTTACCAC
AACTCTATGTATGTTAGTGTAGATTTCTTTCTACCAACAGGAATCTACATACCAATTGAT
ATACCAAGGAATTCAACCATAAAAGAAGTGAAAAATTTACTATGGCAAGAAGCAATCCAC
CATCCTTTATTCAGCAAGCTTCTTAACCCTGAAAGTTACACTTTCACATACATAACAAGT
TTTGGTTTACCAGAGGAAATTGTTGATGAGAGTCGGCATCTCAGTGAGTTTGATATTTTC
CATGAACTGCCGGTGTTGAAACTCGTTCAAAGTAGAGGTAATATTGCAGAGAAACGGGTT
ATACAAGAAATAAACCACCTTACATGCATCAAAAGTAATGAGAGTCGATCGTTTAGAAAA
GACATGCGGGAGTTAGCTGCTCAAGCTTGTAAGGATCGAGATACTCTACACTGGAAATCA
CTTCTTCAACGCCATTTTCCTCCAACCATCATCCCATACCTCAACGAAAGTACTCACTAC
TTAAAAGATTTTGGCCTCATTCAGTTAACATCAGAAAATTCCGAGACGGTATACACCATT
AAAATCAACCCTTCGTGGTCAACGGAACACTTAACGGAAGTCGCACTCCAGACTTGGGTT
TCGAAAACAAAAGCTCGCCTTCCTTCCACCAATAAGGACGATTATGTTTTGAAAGGAAAT
GGAAAAGAGTTTATTGTTGGGAATCACCCAATTTATATGTTTAAGTTCTTACGAAAAGCA
CTGGTATGTAAACCACCTCCAGTTGTTTCTCTGGTTCATGTTGCAAGCGTGAGAAAAATT
TTACCCCAGCAATACCAACTTTTAAAAAAAGTACAGACGAACTTTGCCCCTCCTGTGCCA
GAAAAACATCGAGCAGTTTGGTCACTATGGCAACTCGATGTTATGTTCAAATTAAGAATC
ATAAGAGCTGGTAACGTCAATGCAGGCCAAGAGAGGGACAAAAAGCTAGTGGTCCACGTT
GGTTTATACCATGGAACAGAAACGCTGTGTCCTACCACCTACACTAAAGAACCAGTAAAA
GAGATGGCAGCGGGTAATGAGTACCAGTGGGATGAAGAATGTTTCTTTGATATAAATGCA
GTTAACCTTCCTCGAAATGCGATGCTTTGTCTCGCTATCTGCTCCAGCAAACGAAATGTT
GGTGGGAAATCTAAAAGAAAGGAGTCAACTCAAAAAAATACTCAGCATTCTGCATCTCCT
ATTGCTTGGGCTAATATGATGGTGTTTGATTTCAAAAGATACCTCAAAGCTGGCTTGTAC
CGGTTAAACTGCTGGCAAGTGAACCACGATAATCTTGACTCGAATAACTTGAGTCCTCGT
GGAGGAGTAATGCTTAATCCGGATGTTGAACAAGCTGCTTTCATCGAGATAATGATGCCA
GAGTACCAAGCTACCATCATGTATCCGTCTCTACCGGAAGTGTTAGAAGAAGCAGCTCGT
CAAGCAGTTGTTCGTGAAAGCAACTTAATGACGCGAGGCGCTTCCAAATCTCACATGACA
CAACTGGATGAAGTTGTTAGAAAAGATCGTTTCGACGATTTATTTGATGACGATAAAAGT
TTGTTGTGGCGATTACGAATCGACTGTAGGGAAAAATATCCTGAAGCTCTTTCAAAAGTT
CTCGCATCTGCAAAGTGGAATTCATACAAGAGTGTTGCCATGGTGCAAGCAATGCTCAAT
TCATGGACACCTTTGTCACCGGAGCGCGCCATGGAGCTGTTGGATTGTCAGTTCGCCGAT
GAACATGTGAGGGACTTCGCTGTGAAGTGTTTGGAAAACTTAAGAGATGACGAACTGCAA
CAATACCTTATGCAGTTGGTTCAAGTTGTTAAGTTCGATTCTTACCTGAACAGTAGTTTA
GTTCGTTTCATTCTTCGTCGTGCTTGGAGCAACCGAAAAATCGGACATTTTTTGTTTTGG
CATTTAAAAGCGGAAATTTCGAACACGTTGTTAAATCTTCGTTTCGCGTTGATCATGGAA
GCTTACTTGTATGGTAACTTACCGCATGTGAAGACTTTGTATAAACAACAAGAAGCGCTC
AATAAAATGAGAACTTTGAATGAAAGGGTAAGATCTGAGTTTAGTCAAAAAGATATTAAA
GTTCGGGCTCGACAGGCATTGAAGGATACGGCGAACCAGGATTCATTTAAAGAAGCTCTT
ACTAGTGTTGAATGTCCTCTGGAACCTAACTTGGACTTGGAGGAATTACTTGTTGAAAAA
TGCAAAGTCATGAACAGTAAAATGAGACCTCTATGGTTGGTTTTCAAAAACAAGCAAGTA
CAAGACGGAAGCATGAGCGTTATCTACAAAAACGGAGATGATCTTCGCCAAGATATGCTG
ACTTTACAAACCATATCTATCATGGATATGCTGTGGAAAGCTGAAGGTTTGGACTTGAGA
ATGATCCCGTATGGTTGCCTTGCAACTGGGAAAGGCACGGGCATGATAGAAGTAGTCACG
CATTCAAATACAATAGCCAACATACAGAAGACAAGAGGTGGAAAAATGTCGGCGTTCAGA
CACCAAACGTTAATTGAATGGCTTGAACAGAACAACTCAACCCCGTCAGAATTTGAGCAA
GCAATAGAAAACTTCACGTACTCCTGTGCTGGTTATTGTGTGGCCACGTTTGTGCTTGGT
GTGGGTGATCGGCACTCTGATAATATTATGGTCACTGAGAAAGGACAGCTTTTCCACATT
GACTTTGGGCATATTCTTGGAAACTTTAAGACTAAATTTGGAATCAAAAGAGAGAGAGTT
CCGTTTGTTCTTGCGCACGACTTCGTTCATGTTATCAACAAAGGGAAAACCAACAACAAG
GCTGATTTCGATCAATTCCGAAAACTTTGTGATAATGCATTCTGTATTCTGAGAAAGAAG
GGTTATCTGATCATTACATTGTTTGCGTTGATGCTTCATTCTGGGTTGCCTGAGATGACA
TCGTTGGACCATTTAGAATACTTGCGTGAGACCTTAGCCCTCCACTTAACAGAACAGAAA
GCTCTGCAACAATTCCGCAGCAAGTTTAATAAAGCCCTCACTGATGCATGGGCTACCTCA
GTTAATTGGTTCTTTCATAATGTAGCACGGGATAACACGTGATAAGACAACAATTTCCCC
TTTCTAATTTTATTGCCAAACAAAACAGAGTATCTGATTTTTTTTCTGAGTTTTAAAGTA
GGTTGCTACACTTTGCACGTCCTACTGCATTTTTCCAATTTGCTTCGTTATTTAGAGGTT
CTTTCTTATTATTGGAGGGGCTTTTTAAATAGAGACGTTTAATGTGCAATCATACAATCG
TGCCTAAATTTCTCCTTAAACGTTATAGCAGCCTGCCCGAAAAAATGATGAATATTTGTC
CGTCATGCTTCAACAGACAGTATTGTTTCTTTGCATTCTTTCTTTTCAATATTGTACTTG
TAGAGAAATCTTGGGAGAATTAGGCGCATGTCCATTGTGATTATTGTA
| ProSiteProfiles |
PI3K_adapt-bd_dom (IPR003113) - T[38-129] 30.023 |
| PANTHER |
PI_Kinase (IPR015433) - T[41-1069] 0.0 |
| SMART |
PI3K_adapt-bd_dom (IPR003113) - T[53-132] 4.1E-11 |
| Pfam |
PI3K_adapt-bd_dom (IPR003113) - T[54-131] 2.8E-21 |
| SUPERFAMILY |
Ubiquitin-like_domsf (IPR029071) - T[146-300] 3.79E-12 |
| Pfam |
PI3K_Ras-bd_dom (IPR000341) - T[203-290] 6.9E-7 |
| SMART |
PI3K_C2_dom (IPR002420) - T[321-429] 1.6E-7 |
| ProSiteProfiles |
PI3K_C2_dom (IPR002420) - T[329-500] 27.807 |
| Gene3D |
C2_domain_sf (IPR035892) - T[329-503] 7.0E-43 |
| PIRSF |
PI3K_Vps34 (IPR008290) - T[339-488] 0.087 - T[530-656] 3.0E-15 - T[650-1067] 1.5E-79 |
| Pfam |
PI3K_C2_dom (IPR002420) - T[350-473] 5.4E-19 |
| SMART |
PInositide-3_kin_accessory_dom (IPR001263) - T[525-712] 3.3E-65 |
| ProSiteProfiles |
PInositide-3_kin_accessory_dom (IPR001263) - T[525-702] 34.659 |
| SUPERFAMILY |
ARM-type_fold (IPR016024) - T[533-702] 4.32E-51 |
| Pfam |
PInositide-3_kin_accessory_dom (IPR001263) - T[533-707] 5.3E-52 |
| SUPERFAMILY |
Kinase-like_dom_sf (IPR011009) - T[708-1061] 7.65E-94 |
| ProSiteProfiles |
PI3/4_kinase_cat_dom (IPR000403) - T[802-1051] 68.765 |
| Pfam |
PI3/4_kinase_cat_dom (IPR000403) - T[802-1017] 1.9E-52 |
| SMART |
PI3/4_kinase_cat_dom (IPR000403) - T[803-1068] 9.4E-113 |
| Gene3D |
PI3/4_kinase_cat_sf (IPR036940) - T[858-1070] 1.2E-78 |
| ProSitePatterns |
PI3/4_kinase_CS (IPR018936) - T[905-925] . |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| PK3CB_HUMAN | 40.637 % | 823 | 0 |
| PK3CD_HUMAN | 42.12 % | 797 | 0 |
| PK3CA_HUMAN | 35.912 % | 635 | 0 |