- Transcript 'KH2012:KH.C4.45.v1.A...'
Transcript Model
Transcript Id
KH2012:KH.C4.45.v1.A.SL1-1
Possible name(s)
ITCH; SMURF1; SMURF2
Gene model
Location
KhC4 [1,252,291 / 1,262,341]
Amino acid sequence
Length: 760
>KH.C4.45.v1.A.SL1-1
SKLNFFGLQYAMGVNMFKVQKVRIKVFCAKNICKRDFFRLPDPFAKILVDGSGQCHATGT
CKATLDPKWNQHYDLYVGKSDSITISVWNHRKVHKKHGAGFLGCIRIMSNAINRLKDTGY
QRLDLCKQTKYDQEPVRGQIVVSIESRDLDDRSPSNPVIDARSLIPAQENDLPEGWEARM
TNGRLQYIDHYTRTTQWERPTQPSTRPRRPLSALIISEPDQHQRPRISSSSGSSGPRNSS
SPSVPGESDSTRFRRHKNYMTRNQLHGPSAPLPEGYEQRTTQQGQVYFLHTQTGVSSWHD
PRIPRNLSHINPEDLGPLPSGWELRSTATGRLYYVDHSSRTTQFTDPRIGRYIGQMHNRG
RDGPNEECDQDPQLPRYKRDLVHKLKVLRTELQSQQPQTGHCRLEIKRSEAFEQSYSLIM
KMKPKDLKKRLMVKFTGEDGLDYGGLAREWLYILSHEMLNPYYGLFQYSREDIYTLQINA
DSHINPDHLSYFHFVGRILGMAVYHGHYIDGGFTMLFYKQLLGKPISLEDMEEVDPALYK
SMKWILQNDINGVLDHTFCVDQDSFGERVTHELKPNGVNIPVTEQNKREYVKLYVNWRFL
RGIEAQFLSLSKGFYELIPQHLLRPFDERELELIIGGLGKIDLIDWKKHTKLKHCSQDSN
IVKWFWQAVESFDEEKRARVLQFVTGSSRVPLQGFKALQGSTGTQGPRLFTIQFVDNKTD
CLPKAHTCFNRIDLPPYESYKKLLEKLTCAVENTCGFYTE
Nucleotide sequence
Length: 3,212
>KH2012:KH.C4.45.v1.A.SL1-1
TAGGGTCTATTTTCAATTAGCCTGAAAATTTCAACTAAACATGGAGTTATTGTGACATTA
AGCCAATAAAGTAAAGTCCATTCATCAACCTGTTAATCAAAACTCAACTTCTTTGGACTT
CAATACGCGATGGGTGTCAACATGTTTAAAGTACAGAAAGTCCGAATCAAAGTTTTCTGC
GCAAAGAACATATGCAAGCGGGATTTTTTTCGTCTTCCAGACCCCTTCGCTAAAATATTA
GTAGACGGGTCAGGTCAATGTCACGCCACCGGAACTTGCAAAGCTACTTTGGACCCGAAA
TGGAATCAACACTACGATCTGTACGTTGGGAAGTCAGACAGTATCACGATATCTGTATGG
AACCACAGAAAGGTGCATAAGAAACACGGGGCTGGTTTCCTCGGATGCATACGCATCATG
TCGAACGCCATAAACCGACTGAAAGACACAGGATATCAGCGTCTCGACCTCTGCAAGCAA
ACCAAGTACGACCAGGAACCCGTGAGAGGTCAGATAGTAGTCAGCATCGAAAGTCGTGAT
TTGGACGACCGTTCGCCCTCCAACCCAGTCATAGACGCCAGGTCCCTGATCCCTGCCCAG
GAAAATGACCTTCCGGAAGGCTGGGAGGCAAGGATGACCAATGGACGACTTCAATACATC
GACCATTACACAAGAACGACACAGTGGGAGCGACCAACCCAACCCAGCACTCGCCCTCGT
CGTCCACTCAGCGCTCTCATCATATCTGAGCCTGACCAACACCAAAGACCCCGAATCTCA
AGCAGCAGTGGTAGCTCCGGTCCACGCAACTCATCCAGTCCATCAGTACCAGGCGAGTCC
GACTCGACGAGGTTCCGGCGACACAAAAACTACATGACCCGTAACCAGTTACACGGGCCC
TCTGCTCCCCTGCCTGAGGGTTATGAGCAACGGACTACCCAACAGGGACAAGTCTATTTC
CTTCATACCCAGACCGGGGTTTCGTCGTGGCACGACCCGCGCATACCCAGGAACTTGAGC
CACATTAACCCTGAAGACTTAGGTCCATTGCCATCGGGCTGGGAATTACGCTCGACCGCC
ACAGGTCGACTATATTATGTGGACCACTCGAGCCGGACCACCCAGTTCACCGACCCTCGT
ATTGGCCGTTATATTGGACAGATGCACAACAGAGGAAGGGACGGACCCAATGAAGAATGC
GACCAAGATCCTCAACTGCCACGTTATAAACGCGATTTAGTTCATAAACTTAAAGTTCTT
CGAACGGAGTTGCAATCCCAACAACCTCAGACTGGACATTGTCGATTGGAAATCAAACGT
TCGGAGGCGTTTGAGCAGTCCTACAGCCTCATTATGAAAATGAAACCTAAAGATCTAAAG
AAACGACTTATGGTTAAGTTTACCGGTGAAGATGGTTTAGATTACGGTGGACTAGCAAGG
GAGTGGCTGTACATTCTATCCCATGAAATGCTTAACCCCTACTACGGCTTATTTCAGTAT
TCCCGCGAAGATATCTACACTCTTCAAATCAACGCCGATTCCCATATCAACCCTGACCAC
CTTTCCTACTTCCATTTCGTGGGTCGTATATTGGGCATGGCGGTCTACCACGGCCACTAC
ATAGACGGTGGCTTCACCATGCTATTCTATAAGCAGCTGCTAGGAAAACCTATCTCACTG
GAAGATATGGAAGAGGTCGATCCAGCATTGTACAAGTCAATGAAGTGGATTCTACAAAAC
GATATAAACGGAGTGCTCGACCACACGTTCTGTGTTGACCAAGATTCATTCGGTGAACGC
GTAACCCACGAGTTAAAACCAAACGGGGTAAACATACCCGTCACCGAGCAAAACAAACGA
GAATACGTCAAGTTGTATGTGAACTGGAGGTTTCTCCGAGGCATCGAAGCTCAGTTCTTA
TCTCTTTCAAAGGGATTCTACGAGCTTATTCCTCAACATCTTTTGCGTCCTTTTGATGAG
CGGGAGCTGGAGCTGATCATCGGAGGACTCGGGAAGATTGACCTCATTGATTGGAAGAAA
CACACTAAGCTGAAGCATTGCTCACAAGACTCAAACATCGTCAAATGGTTTTGGCAAGCT
GTGGAGAGTTTTGATGAAGAAAAAAGAGCAAGAGTGCTGCAGTTCGTAACTGGTTCATCG
CGGGTTCCACTACAAGGTTTTAAAGCGTTACAAGGTTCAACTGGTACACAAGGTCCACGG
TTGTTCACCATTCAATTTGTTGACAATAAAACCGACTGCTTACCGAAAGCCCATACTTGT
TTTAACCGGATCGACCTCCCACCTTACGAATCGTATAAAAAGCTACTTGAAAAGCTCACC
TGCGCTGTTGAAAACACATGTGGATTCTACACCGAGTAATAAAGGGTCTACCATGGAAAA
GTCAGAGTTGCAGTGTTAAATCAATGCTTGACTAAAGACACACTTTCAATAGAACGAAAA
ATGTTTTATGACCGATTTAAATACGGAACCCCTGATCCAAGGTGCTAACAATATCAATGG
AAACTCAGCTTAACCTCCCGCTCAGCTTAATTTAAAATTTGCGCGAAGCTTGCGCCAACT
ACCTCATTGTACATAGACCACGGTCGACAATCACTTTAAGAAAATTCAGTCGCGCCTGCT
AATTTATGTATGTGACGTAATTCTCGCAAACTTTACATGATTCCACACTCAACAACGAAT
GTGCCAGCGTTCATAATTATACTTTCACTTTACCCGTTCTGTACTTTTAATTAAATGACC
ACTTGCAAGTTTTTTTGAGCCTGTCTTGGTCACCGCGTGAATATTCGTGACGAATCATAT
GAAAACTATAGTCACGTGCCTGAATTTCGGTATTTTCGTTACATCTGAACTTAACAGTTT
GGTTTACAAAAACTGATCAGCATACTTGTTTTCTATGTTTGTTCCGAAAACTCGTCGATT
TTCCTGCACTTCGTTTCTCTATCAAGATATGAATGTCTCTCATCTTCCGCGATTTCTTTT
TTTTCCAAGTTATGGAAACACCTTCAATCGTTTCTTTTCACTTGTTGACGTTGTGTGCAG
AAAAGAGCACCAAGCGAATGTCTAACGCGAGATTTCAGTGTTACCGCCCCCTATTTTCTT
GTATCAAGTGTAAACAATCTTTATTCTTATTACTTATTATTACGTTGCGCGGTGCCGCAG
GAGCATTTAATAAATCGACATTTGTTTCTTGA
| PIRSF |
E3_ub_ligase_SMURF1 (IPR024928) - T[9-153] 1.6E-18 - T[127-760] 3.4E-210 |
| Gene3D |
C2_domain_sf (IPR035892) - T[17-147] 6.2E-31 |
| ProSiteProfiles |
C2_dom (IPR000008) - T[21-106] 10.042 |
| SMART |
C2_dom (IPR000008) - T[21-124] 8.2E-12 |
| Pfam |
C2_dom (IPR000008) - T[21-111] 2.9E-12 |
| SUPERFAMILY |
WW_dom_sf (IPR036020) - T[168-203] 2.36E-11 - T[264-306] 3.81E-10 - T[311-351] 8.53E-12 |
| ProSiteProfiles |
WW_dom (IPR001202) - T[170-202] 14.166 - T[270-303] 12.57 - T[316-349] 15.841 |
| SMART |
WW_dom (IPR001202) - T[171-202] 5.4E-6 - T[271-303] 4.5E-8 - T[317-349] 2.2E-8 |
| Pfam |
WW_dom (IPR001202) - T[172-200] 1.1E-7 - T[272-301] 2.3E-6 - T[318-347] 6.8E-8 |
| CDD |
WW_dom (IPR001202) - T[173-201] 2.88072E-7 - T[273-303] 1.63198E-7 - T[319-349] 4.84485E-8 |
| ProSitePatterns |
WW_dom (IPR001202) - T[322-347] . |
| SUPERFAMILY |
Hect_E3_ubiquitin_ligase (IPR035983) - T[389-753] 5.36E-122 |
| CDD |
HECT_dom (IPR000569) - T[402-757] 4.64119E-162 |
| SMART |
HECT_dom (IPR000569) - T[421-760] 1.1E-155 |
| ProSiteProfiles |
HECT_dom (IPR000569) - T[423-760] 107.317 |
| Pfam |
HECT_dom (IPR000569) - T[453-758] 2.7E-97 |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| ITCH_HUMAN | 43.655 % | 493 | 1.54E-162 |
| SMUF1_HUMAN | 62.1 % | 966 | 0 |
| SMUF2_HUMAN | 66.976 % | 1040 | 0 |