- Transcript 'Phmamm.CG.MTP2014.S3...' >
- Transcript 'KH2012:KH.C4.45.v2.A...'
Transcript Model
Transcript Id
KH2012:KH.C4.45.v2.A.SL2-1
Possible name(s)
ITCH; SMURF1; SMURF2
Gene model
Location
KhC4 [1,252,291 / 1,269,066]
Amino acid sequence
Length: 765
>KH.C4.45.v2.A.SL2-1
IVLKVDAEELIMSSASGSTRRNGTMKLRLTVFCAKNICKRDFFRLPDPFAKILVDGSGQC
HATGTCKATLDPKWNQHYDLYVGKSDSITISVWNHRKVHKKHGAGFLGCIRIMSNAINRL
KDTGYQRLDLCKQTKYDQEPVRGQIVVSIESRDLDDRSPSNPVIDARSLIPAQENDLPEG
WEARMTNGRLQYIDHYTRTTQWERPTQPSTRPRRPLSALIISEPDQHQRPRISSSSGSSG
PRNSSSPSVPGESDSTRFRRHKNYMTRNQLHGPSAPLPEGYEQRTTQQGQVYFLHTQTGV
SSWHDPRIPRNLSHINPEDLGPLPSGWELRSTATGRLYYVDHSSRTTQFTDPRIGRYIGQ
MHNRGRDGPNEECDQDPQLPRYKRDLVHKLKVLRTELQSQQPQTGHCRLEIKRSEAFEQS
YSLIMKMKPKDLKKRLMVKFTGEDGLDYGGLAREWLYILSHEMLNPYYGLFQYSREDIYT
LQINADSHINPDHLSYFHFVGRILGMAVYHGHYIDGGFTMLFYKQLLGKPISLEDMEEVD
PALYKSMKWILQNDINGVLDHTFCVDQDSFGERVTHELKPNGVNIPVTEQNKREYVKLYV
NWRFLRGIEAQFLSLSKGFYELIPQHLLRPFDERELELIIGGLGKIDLIDWKKHTKLKHC
SQDSNIVKWFWQAVESFDEEKRARVLQFVTGSSRVPLQGFKALQGSTGTQGPRLFTIQFV
DNKTDCLPKAHTCFNRIDLPPYESYKKLLEKLTCAVENTCGFYTE
Nucleotide sequence
Length: 3,212
>KH2012:KH.C4.45.v2.A.SL2-1
AGTATTAGGCAGTTAATCAAGGTGTAACTTGTACGTTGCTGTCTTTTATCTTTGTGGTCA
GTTGTATCTGACTAAGTGTAAATTGTTTTGAAAGTGGATGCAGAAGAATTAATCATGTCA
TCTGCATCTGGTTCAACTCGAAGAAATGGAACCATGAAGCTAAGGCTTACAGTTTTCTGC
GCAAAGAACATATGCAAGCGGGATTTTTTTCGTCTTCCAGACCCCTTCGCTAAAATATTA
GTAGACGGGTCAGGTCAATGTCACGCCACCGGAACTTGCAAAGCTACTTTGGACCCGAAA
TGGAATCAACACTACGATCTGTACGTTGGGAAGTCAGACAGTATCACGATATCTGTATGG
AACCACAGAAAGGTGCATAAGAAACACGGGGCTGGTTTCCTCGGATGCATACGCATCATG
TCGAACGCCATAAACCGACTGAAAGACACAGGATATCAGCGTCTCGACCTCTGCAAGCAA
ACCAAGTACGACCAGGAACCCGTGAGAGGTCAGATAGTAGTCAGCATCGAAAGTCGTGAT
TTGGACGACCGTTCGCCCTCCAACCCAGTCATAGACGCCAGGTCCCTGATCCCTGCCCAG
GAAAATGACCTTCCGGAAGGCTGGGAGGCAAGGATGACCAATGGACGACTTCAATACATC
GACCATTACACAAGAACGACACAGTGGGAGCGACCAACCCAACCCAGCACTCGCCCTCGT
CGTCCACTCAGCGCTCTCATCATATCTGAGCCTGACCAACACCAAAGACCCCGAATCTCA
AGCAGCAGTGGTAGCTCCGGTCCACGCAACTCATCCAGTCCATCAGTACCAGGCGAGTCC
GACTCGACGAGGTTCCGGCGACACAAAAACTACATGACCCGTAACCAGTTACACGGGCCC
TCTGCTCCCCTGCCTGAGGGTTATGAGCAACGGACTACCCAACAGGGACAAGTCTATTTC
CTTCATACCCAGACCGGGGTTTCGTCGTGGCACGACCCGCGCATACCCAGGAACTTGAGC
CACATTAACCCTGAAGACTTAGGTCCATTGCCATCGGGCTGGGAATTACGCTCGACCGCC
ACAGGTCGACTATATTATGTGGACCACTCGAGCCGGACCACCCAGTTCACCGACCCTCGT
ATTGGCCGTTATATTGGACAGATGCACAACAGAGGAAGGGACGGACCCAATGAAGAATGC
GACCAAGATCCTCAACTGCCACGTTATAAACGCGATTTAGTTCATAAACTTAAAGTTCTT
CGAACGGAGTTGCAATCCCAACAACCTCAGACTGGACATTGTCGATTGGAAATCAAACGT
TCGGAGGCGTTTGAGCAGTCCTACAGCCTCATTATGAAAATGAAACCTAAAGATCTAAAG
AAACGACTTATGGTTAAGTTTACCGGTGAAGATGGTTTAGATTACGGTGGACTAGCAAGG
GAGTGGCTGTACATTCTATCCCATGAAATGCTTAACCCCTACTACGGCTTATTTCAGTAT
TCCCGCGAAGATATCTACACTCTTCAAATCAACGCCGATTCCCATATCAACCCTGACCAC
CTTTCCTACTTCCATTTCGTGGGTCGTATATTGGGCATGGCGGTCTACCACGGCCACTAC
ATAGACGGTGGCTTCACCATGCTATTCTATAAGCAGCTGCTAGGAAAACCTATCTCACTG
GAAGATATGGAAGAGGTCGATCCAGCATTGTACAAGTCAATGAAGTGGATTCTACAAAAC
GATATAAACGGAGTGCTCGACCACACGTTCTGTGTTGACCAAGATTCATTCGGTGAACGC
GTAACCCACGAGTTAAAACCAAACGGGGTAAACATACCCGTCACCGAGCAAAACAAACGA
GAATACGTCAAGTTGTATGTGAACTGGAGGTTTCTCCGAGGCATCGAAGCTCAGTTCTTA
TCTCTTTCAAAGGGATTCTACGAGCTTATTCCTCAACATCTTTTGCGTCCTTTTGATGAG
CGGGAGCTGGAGCTGATCATCGGAGGACTCGGGAAGATTGACCTCATTGATTGGAAGAAA
CACACTAAGCTGAAGCATTGCTCACAAGACTCAAACATCGTCAAATGGTTTTGGCAAGCT
GTGGAGAGTTTTGATGAAGAAAAAAGAGCAAGAGTGCTGCAGTTCGTAACTGGTTCATCG
CGGGTTCCACTACAAGGTTTTAAAGCGTTACAAGGTTCAACTGGTACACAAGGTCCACGG
TTGTTCACCATTCAATTTGTTGACAATAAAACCGACTGCTTACCGAAAGCCCATACTTGT
TTTAACCGGATCGACCTCCCACCTTACGAATCGTATAAAAAGCTACTTGAAAAGCTCACC
TGCGCTGTTGAAAACACATGTGGATTCTACACCGAGTAATAAAGGGTCTACCATGGAAAA
GTCAGAGTTGCAGTGTTAAATCAATGCTTGACTAAAGACACACTTTCAATAGAACGAAAA
ATGTTTTATGACCGATTTAAATACGGAACCCCTGATCCAAGGTGCTAACAATATCAATGG
AAACTCAGCTTAACCTCCCGCTCAGCTTAATTTAAAATTTGCGCGAAGCTTGCGCCAACT
ACCTCATTGTACATAGACCACGGTCGACAATCACTTTAAGAAAATTCAGTCGCGCCTGCT
AATTTATGTATGTGACGTAATTCTCGCAAACTTTACATGATTCCACACTCAACAACGAAT
GTGCCAGCGTTCATAATTATACTTTCACTTTACCCGTTCTGTACTTTTAATTAAATGACC
ACTTGCAAGTTTTTTTGAGCCTGTCTTGGTCACCGCGTGAATATTCGTGACGAATCATAT
GAAAACTATAGTCACGTGCCTGAATTTCGGTATTTTCGTTACATCTGAACTTAACAGTTT
GGTTTACAAAAACTGATCAGCATACTTGTTTTCTATGTTTGTTCCGAAAACTCGTCGATT
TTCCTGCACTTCGTTTCTCTATCAAGATATGAATGTCTCTCATCTTCCGCGATTTCTTTT
TTTTCCAAGTTATGGAAACACCTTCAATCGTTTCTTTTCACTTGTTGACGTTGTGTGCAG
AAAAGAGCACCAAGCGAATGTCTAACGCGAGATTTCAGTGTTACCGCCCCCTATTTTCTT
GTATCAAGTGTAAACAATCTTTATTCTTATTACTTATTATTACGTTGCGCGGTGCCGCAG
GAGCATTTAATAAATCGACATTTGTTTCTTGA
| PIRSF |
E3_ub_ligase_SMURF1 (IPR024928) - T[12-161] 4.2E-19 - T[131-765] 3.3E-210 |
| Gene3D |
C2_domain_sf (IPR035892) - T[22-152] 4.9E-31 |
| SMART |
C2_dom (IPR000008) - T[26-129] 7.6E-12 |
| Pfam |
C2_dom (IPR000008) - T[26-116] 1.7E-12 |
| ProSiteProfiles |
C2_dom (IPR000008) - T[26-111] 10.042 |
| SUPERFAMILY |
WW_dom_sf (IPR036020) - T[173-208] 2.5E-11 - T[269-311] 3.97E-10 - T[316-356] 7.87E-12 |
| ProSiteProfiles |
WW_dom (IPR001202) - T[175-207] 14.166 - T[275-308] 12.57 - T[321-354] 15.841 |
| SMART |
WW_dom (IPR001202) - T[176-207] 5.4E-6 - T[276-308] 4.5E-8 - T[322-354] 2.2E-8 |
| Pfam |
WW_dom (IPR001202) - T[177-205] 1.1E-7 - T[277-306] 2.3E-6 - T[323-352] 6.9E-8 |
| CDD |
WW_dom (IPR001202) - T[178-206] 2.81543E-7 - T[278-308] 1.54881E-7 - T[324-354] 4.59804E-8 |
| ProSitePatterns |
WW_dom (IPR001202) - T[327-352] . |
| SUPERFAMILY |
Hect_E3_ubiquitin_ligase (IPR035983) - T[394-758] 5.49E-122 |
| CDD |
HECT_dom (IPR000569) - T[407-762] 1.75191E-162 |
| SMART |
HECT_dom (IPR000569) - T[426-765] 1.1E-155 |
| ProSiteProfiles |
HECT_dom (IPR000569) - T[428-765] 107.317 |
| Pfam |
HECT_dom (IPR000569) - T[458-763] 2.8E-97 |
| Protein Name | Identity | Bit Score | e-value |
|---|---|---|---|
| ITCH_HUMAN | 43.655 % | 494 | 5.93E-163 |
| SMUF1_HUMAN | 62.357 % | 978 | 0 |
| SMUF2_HUMAN | 67.057 % | 1055 | 0 |